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Aliases for MIR4435-1 Gene

Subcategory (RNA class) for MIR4435-1 Gene


Quality Score for this RNA gene is


Aliases for MIR4435-1 Gene

  • MicroRNA 4435-1 2 3
  • Hsa-Mir-4435-1 3

External Ids for MIR4435-1 Gene

Previous GeneCards Identifiers for MIR4435-1 Gene

  • GC02U902445
  • GC02P087934

Summaries for MIR4435-1 Gene

Entrez Gene Summary for MIR4435-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4435-1 Gene

MIR4435-1 (MicroRNA 4435-1) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4435-1 Gene

Genomics for MIR4435-1 Gene

Genomic Location for MIR4435-1 Gene

87,629,755 bp from pter
87,629,834 bp from pter
80 bases
Plus strand

Genomic View for MIR4435-1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR4435-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4435-1 Gene

No data available for Regulatory Elements for MIR4435-1 Gene

Proteins for MIR4435-1 Gene

Post-translational modifications for MIR4435-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4435-1 Gene

Domains for MIR4435-1 Gene

Gene Families for MIR4435-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4435-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4435-1 Gene

Function for MIR4435-1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4435-1 Gene

Localization for MIR4435-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4435-1 Gene

Pathways for MIR4435-1 Gene

SuperPathways for MIR4435-1 Gene

No Data Available

Interacting Proteins for MIR4435-1 Gene

Gene Ontology (GO) - Biological Process for MIR4435-1 Gene


No data available for Pathways by source for MIR4435-1 Gene

Transcripts for MIR4435-1 Gene

mRNA/cDNA for MIR4435-1 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4435-1 Gene

No ASD Table

Relevant External Links for MIR4435-1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4435-1 Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR4435-1 Gene

Orthologs for MIR4435-1 Gene

Evolution for MIR4435-1 Gene

Gene Tree for MIR4435-1 (if available)
Gene Tree for MIR4435-1 (if available)

No data available for Orthologs for MIR4435-1 Gene

Paralogs for MIR4435-1 Gene

No data available for Paralogs for MIR4435-1 Gene

Variants for MIR4435-1 Gene

Sequence variations from dbSNP and Humsavar for MIR4435-1 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs908901 -- 87,628,048(+) GGGTC(C/G)TAGGG upstream-variant-2KB
rs908903 -- 87,628,148(+) ggaaa(C/T)ggagg upstream-variant-2KB
rs56324656 -- 87,630,279(+) CACCC(A/T)CTTTG downstream-variant-500B
rs71261509 -- 87,629,583(+) TGCAG(C/T)TGGTG upstream-variant-2KB
rs72624665 -- 87,629,507(+) ATCTA(G/T)TTCTA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4435-1 Gene

Variant ID Type Subtype PubMed ID
nsv874473 CNV Gain 21882294
dgv1214e1 CNV Complex 17122850
dgv1215e1 CNV Complex 17122850
nsv428398 CNV Loss 18775914
dgv4207n71 CNV Gain 21882294
esv26476 CNV Gain+Loss 19812545
nsv516958 CNV Gain+Loss 19592680
dgv4219n71 CNV Gain 21882294
dgv61n16 CNV Deletion 17901297
nsv10068 CNV Gain+Loss 18304495
dgv4222n71 CNV Gain 21882294
nsv829491 CNV Gain 20364138
esv33317 CNV Gain 17666407
dgv4225n71 CNV Gain 21882294
dgv4226n71 CNV Gain 21882294
essv14988 CNV CNV 17122850
nsv834286 CNV Gain 17160897
esv2422072 CNV Deletion 20811451
nsv441767 CNV CNV 18776908
nsv874573 CNV Gain 21882294
nsv521956 CNV Loss 19592680
nsv428402 CNV Loss 18775914
dgv1236e1 CNV Complex 17122850
nsv821628 CNV Gain 15273396
nsv469744 CNV Gain 16826518
dgv4273n71 CNV Gain 21882294
nsv874846 CNV Gain 21882294
esv26325 CNV Gain+Loss 19812545
dgv4274n71 CNV Gain 21882294
nsv10126 CNV Gain+Loss 18304495
dgv4275n71 CNV Gain 21882294
nsv2876 CNV Insertion 18451855
dgv4276n71 CNV Gain 21882294
nsv818077 CNV Gain 17921354
nsv522475 CNV Gain 19592680
nsv441774 CNV CNV 18776908

Relevant External Links for MIR4435-1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR4435-1 Gene

Disorders for MIR4435-1 Gene

No disorders were found for MIR4435-1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR4435-1 Gene

Publications for MIR4435-1 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3

Products for MIR4435-1 Gene

Sources for MIR4435-1 Gene

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