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Aliases for MIR4434 Gene

Subcategory (RNA class) for MIR4434 Gene

miRNA

Quality Score for this RNA gene is

2

Aliases for MIR4434 Gene

  • MicroRNA 4434 2 3
  • Hsa-Mir-4434 3

External Ids for MIR4434 Gene

Summaries for MIR4434 Gene

Entrez Gene Summary for MIR4434 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4434 Gene

MIR4434 (MicroRNA 4434) is a RNA Gene, and belongs to miRNA RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4434 Gene

Genomics for MIR4434 Gene

Genomic Location for MIR4434 Gene

Start:
64,525,513 bp from pter
End:
64,525,565 bp from pter
Size:
53 bases
Orientation:
Plus strand

Genomic View for MIR4434 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR4434 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4434 Gene

No data available for Regulatory Elements for MIR4434 Gene

Proteins for MIR4434 Gene

Post-translational modifications for MIR4434 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4434 Gene

Domains for MIR4434 Gene

Gene Families for MIR4434 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR4434: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR4434 Gene

Function for MIR4434 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR4434 Gene

Localization for MIR4434 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR4434 Gene

Pathways for MIR4434 Gene

SuperPathways for MIR4434 Gene

No Data Available

Interacting Proteins for MIR4434 Gene

Gene Ontology (GO) - Biological Process for MIR4434 Gene

None

No data available for Pathways by source for MIR4434 Gene

Transcripts for MIR4434 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4434 Gene

No ASD Table

Relevant External Links for MIR4434 Gene

GeneLoc Exon Structure for
MIR4434
ECgene alternative splicing isoforms for
MIR4434

No data available for mRNA/cDNA for MIR4434 Gene

Expression for MIR4434 Gene

No Expression Related Data Available

Orthologs for MIR4434 Gene

No data available for Orthologs and Evolution for MIR4434 Gene

Paralogs for MIR4434 Gene

No data available for Paralogs for MIR4434 Gene

Variants for MIR4434 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4434 Gene

Variant ID Type Subtype PubMed ID
nsv7313 OTHER Inversion 18451855
nsv834245 CNV Gain 17160897
nsv2754 CNV Insertion 18451855

Relevant External Links for MIR4434 Gene

HapMap Linkage Disequilibrium report
MIR4434

No data available for Sequence variations from dbSNP and Humsavar for MIR4434 Gene

Disorders for MIR4434 Gene

No disorders were found for MIR4434 Gene.

No data available for UniProtKB/Swiss-Prot for MIR4434 Gene

Publications for MIR4434 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3

Products for MIR4434 Gene

Sources for MIR4434 Gene

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