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Aliases for MIR4432 Gene

Subcategory (RNA class) for MIR4432 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4432 Gene

  • MicroRNA 4432 2 3 5
  • Hsa-Mir-4432 3

External Ids for MIR4432 Gene

Previous GeneCards Identifiers for MIR4432 Gene

  • GC02U902441
  • GC02M060616

Summaries for MIR4432 Gene

Entrez Gene Summary for MIR4432 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4432 Gene

MIR4432 (MicroRNA 4432) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4432 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4432 Gene

Genomics for MIR4432 Gene

Genomic Location for MIR4432 Gene

Chromosome:
2
Start:
60,387,362 bp from pter
End:
60,387,445 bp from pter
Size:
84 bases
Orientation:
Minus strand

Genomic View for MIR4432 Gene

Genes around MIR4432 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4432 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4432 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4432 Gene

ORGUL Member Location for MIR4432 Gene

ORGUL Member Location for MIR4432 gene

No data available for Regulatory Elements for MIR4432 Gene

Proteins for MIR4432 Gene

Post-translational modifications for MIR4432 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4432 Gene

Domains & Families for MIR4432 Gene

Gene Families for MIR4432 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4432: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4432 Gene

Function for MIR4432 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4432
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4432 Gene

Localization for MIR4432 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4432 Gene

Pathways & Interactions for MIR4432 Gene

SuperPathways for MIR4432 Gene

No Data Available

Interacting Proteins for MIR4432 Gene

Gene Ontology (GO) - Biological Process for MIR4432 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4432 Gene

Drugs & Compounds for MIR4432 Gene

No Compound Related Data Available

Transcripts for MIR4432 Gene

mRNA/cDNA for MIR4432 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4432
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4432 Gene

No ASD Table

Relevant External Links for MIR4432 Gene

GeneLoc Exon Structure for
MIR4432
ECgene alternative splicing isoforms for
MIR4432

Expression for MIR4432 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4432 Gene:

MIR4432
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4432 Gene

Orthologs for MIR4432 Gene

Evolution for MIR4432 Gene

ENSEMBL:
Gene Tree for MIR4432 (if available)
TreeFam:
Gene Tree for MIR4432 (if available)

No data available for Orthologs for MIR4432 Gene

Paralogs for MIR4432 Gene

No data available for Paralogs for MIR4432 Gene

Variants for MIR4432 Gene

Sequence variations from dbSNP and Humsavar for MIR4432 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1000503568 -- 60,389,060(+) GGAAA(G/T)GAAAG intron-variant, upstream-variant-2KB
rs1000721893 -- 60,388,844(+) TGGTG(A/G)CGCAT intron-variant, upstream-variant-2KB
rs1002227155 -- 60,387,215(+) CATGT(C/G)AGAGG intron-variant, downstream-variant-500B
rs1002386306 -- 60,388,802(+) TGAAA(C/T)CCCGT intron-variant, upstream-variant-2KB
rs1004686026 -- 60,386,963(+) GGGAG(A/G)ACCAG intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4432 Gene

Variant ID Type Subtype PubMed ID
nsv834204 CNV gain 17160897

Relevant External Links for MIR4432 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4432

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4432 Gene

Disorders for MIR4432 Gene

Relevant External Links for MIR4432

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4432

No disorders were found for MIR4432 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4432 Gene

Publications for MIR4432 Gene

  1. Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. (PMID: 24927181) Navarini AA … Barker JN (Nature communications 2014) 3 60
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 60
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4432 Gene

Sources for MIR4432 Gene

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