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Aliases for MIR4430 Gene

Subcategory (RNA class) for MIR4430 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4430 Gene

  • MicroRNA 4430 2 3 5
  • Hsa-Mir-4430 3

External Ids for MIR4430 Gene

Previous GeneCards Identifiers for MIR4430 Gene

  • GC02U902436
  • GC02P033645

Summaries for MIR4430 Gene

Entrez Gene Summary for MIR4430 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4430 Gene

MIR4430 (MicroRNA 4430) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4430 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4430 Gene

Genomics for MIR4430 Gene

GeneHancer (GH) Regulatory Elements for MIR4430 Gene

Promoters and enhancers for MIR4430 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I033411 Enhancer 1 Ensembl ENCODE 0.4 -6.4 -6358 1.7 ATF1 FOXA2 SIN3A RAD21 ETS1 FOS ATF7 CREM REST SP1 RASGRP3 ENSG00000206951 LTBP1 MIR4430 PIR50335
GH02I033420 Enhancer 0.3 FANTOM5 0.8 +2.4 2361 0.5 RASGRP3 MIR4430
GH02I033426 Enhancer 0.5 ENCODE 0.4 +8.3 8342 1.1 JUND NFIC PKNOX1 NFIA L3MBTL2 POLR2A REST RASGRP3 MIR4430
GH02I033396 Enhancer 0.6 ENCODE 0.3 -21.9 -21887 0.1 GATAD2A TEAD1 MAX CEBPG TEAD3 SP1 CEBPA TCF7 SMAD4 MIR4430 PIR50335 LTBP1
GH02I033425 Enhancer 0.4 ENCODE 0.4 +7.3 7332 0.3 JUND JUN EGR2 MIR4430 RASGRP3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4430 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4430 Gene

Genomic Locations for MIR4430 Gene
chr2:33,418,516-33,418,564
(GRCh38/hg38)
Size:
49 bases
Orientation:
Plus strand
chr2:33,643,583-33,643,631
(GRCh37/hg19)

Genomic View for MIR4430 Gene

Genes around MIR4430 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4430 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4430 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4430 Gene

Proteins for MIR4430 Gene

Post-translational modifications for MIR4430 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4430 Gene

Domains & Families for MIR4430 Gene

Gene Families for MIR4430 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4430: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4430 Gene

Function for MIR4430 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4430 Gene

Localization for MIR4430 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4430 Gene

Pathways & Interactions for MIR4430 Gene

SuperPathways for MIR4430 Gene

No Data Available

Interacting Proteins for MIR4430 Gene

Gene Ontology (GO) - Biological Process for MIR4430 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4430 Gene

Drugs & Compounds for MIR4430 Gene

No Compound Related Data Available

Transcripts for MIR4430 Gene

mRNA/cDNA for MIR4430 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4430 Gene

No ASD Table

Relevant External Links for MIR4430 Gene

GeneLoc Exon Structure for
MIR4430
ECgene alternative splicing isoforms for
MIR4430

Expression for MIR4430 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4430 Gene:

MIR4430
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4430 Gene

Orthologs for MIR4430 Gene

Evolution for MIR4430 Gene

ENSEMBL:
Gene Tree for MIR4430 (if available)
TreeFam:
Gene Tree for MIR4430 (if available)

No data available for Orthologs for MIR4430 Gene

Paralogs for MIR4430 Gene

No data available for Paralogs for MIR4430 Gene

Variants for MIR4430 Gene

Sequence variations from dbSNP and Humsavar for MIR4430 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1003108184 -- 33,418,264(+) A/T upstream_transcript_variant
rs1003808239 -- 33,417,404(+) C/A upstream_transcript_variant
rs1004649970 -- 33,417,954(+) T/C upstream_transcript_variant
rs1005839216 -- 33,419,015(+) G/A downstream_transcript_variant
rs1006723333 -- 33,418,839(+) T/G downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4430 Gene

Variant ID Type Subtype PubMed ID
esv3590286 CNV loss 21293372
esv3891725 CNV gain 25118596

Additional Variant Information for MIR4430 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4430

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4430 Gene

Disorders for MIR4430 Gene

Additional Disease Information for MIR4430

No disorders were found for MIR4430 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4430 Gene

Publications for MIR4430 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4430 Gene

Sources for MIR4430 Gene

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