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Aliases for MIR4429 Gene

Subcategory (RNA class) for MIR4429 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4429 Gene

  • MicroRNA 4429 2 3 5
  • Hsa-Mir-4429 3
  • Mir-4429 3

External Ids for MIR4429 Gene

Previous GeneCards Identifiers for MIR4429 Gene

  • GC02U902448
  • GC02M011682

Summaries for MIR4429 Gene

Entrez Gene Summary for MIR4429 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4429 Gene

MIR4429 (MicroRNA 4429) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4429 Gene

Genomics for MIR4429 Gene

Regulatory Elements for MIR4429 Gene

Enhancers for MIR4429 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02F011539 1.3 Ensembl ENCODE 0.8 -1.8 -1797 6.9 PKNOX1 MLX ARID4B SIN3A YBX1 DMAP1 YY1 SLC30A9 ZNF143 ZNF207 C2orf50 LPIN1 LOC100506405 MIR4429 TRG-CCC7-1
GH02F011531 1.3 Ensembl ENCODE 0.4 +6.4 6435 5.2 PKNOX1 MLX ARID4B SIN3A DMAP1 ZNF48 BRCA1 FOS ZNF263 SP5 LPIN1 LOC100506405 GC02P011532 MIR4429
GH02F011550 0.8 ENCODE 0.4 -10.1 -10134 1.0 ELF3 PKNOX1 SAP130 TEAD4 CEBPG RAD21 POLR2A ZNF263 GATAD2A NFIA TRG-CCC7-1 MIR4429
GH02F011549 0.2 ENCODE 0.4 -8.7 -8715 0.1 TRG-CCC7-1 MIR4429
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4429 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4429 Gene

Chromosome:
2
Start:
11,540,605 bp from pter
End:
11,540,677 bp from pter
Size:
73 bases
Orientation:
Minus strand

Genomic View for MIR4429 Gene

Genes around MIR4429 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4429 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4429 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4429 Gene

ORGUL Member Location for MIR4429 Gene

ORGUL Member Location for MIR4429 gene

Proteins for MIR4429 Gene

Post-translational modifications for MIR4429 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4429 Gene

Domains & Families for MIR4429 Gene

Gene Families for MIR4429 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4429: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4429 Gene

Function for MIR4429 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4429 Gene

Localization for MIR4429 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4429 Gene

Pathways & Interactions for MIR4429 Gene

SuperPathways for MIR4429 Gene

No Data Available

Interacting Proteins for MIR4429 Gene

Gene Ontology (GO) - Biological Process for MIR4429 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4429 Gene

Transcripts for MIR4429 Gene

mRNA/cDNA for MIR4429 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4429 Gene

No ASD Table

Relevant External Links for MIR4429 Gene

GeneLoc Exon Structure for
MIR4429
ECgene alternative splicing isoforms for
MIR4429

Expression for MIR4429 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4429 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4429 Gene:

MIR4429
genes like me logo Genes that share expression patterns with MIR4429: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4429 Gene

Orthologs for MIR4429 Gene

Evolution for MIR4429 Gene

ENSEMBL:
Gene Tree for MIR4429 (if available)
TreeFam:
Gene Tree for MIR4429 (if available)

No data available for Orthologs for MIR4429 Gene

Paralogs for MIR4429 Gene

No data available for Paralogs for MIR4429 Gene

Variants for MIR4429 Gene

Sequence variations from dbSNP and Humsavar for MIR4429 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs111431328 -- 11,542,238(+) CTTTG(C/T)TTCTC intron-variant, upstream-variant-2KB
rs11287340 -- 11,541,454(+) GGGGC(-/C)ATGGG intron-variant, upstream-variant-2KB
rs114094409 -- 11,542,330(+) CCCCG(A/C)AGGCC intron-variant, upstream-variant-2KB
rs114509885 -- 11,541,404(+) ACAGG(C/T)GGGTT intron-variant, upstream-variant-2KB
rs114608856 -- 11,540,586(+) CAGCT(C/T)GGGGC intron-variant, downstream-variant-500B

Relevant External Links for MIR4429 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4429

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4429 Gene

Disorders for MIR4429 Gene

Relevant External Links for MIR4429

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4429

No disorders were found for MIR4429 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4429 Gene

Publications for MIR4429 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4429 Gene

Sources for MIR4429 Gene

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