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Aliases for MIR4426 Gene

Subcategory (RNA class) for MIR4426 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4426 Gene

  • MicroRNA 4426 2 3 5
  • Hsa-Mir-4426 3

External Ids for MIR4426 Gene

Previous GeneCards Identifiers for MIR4426 Gene

  • GC01U903269

Summaries for MIR4426 Gene

Entrez Gene Summary for MIR4426 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4426 Gene

MIR4426 (MicroRNA 4426) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4426 Gene

Genomics for MIR4426 Gene

Regulatory Elements for MIR4426 Gene

Enhancers for MIR4426 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G192788 1.2 FANTOM5 Ensembl dbSUPER 0.2 +72.1 72050 0.4 PKNOX1 ZNF316 JUND NFE2 ZNF24 FOS MAFK NFE2L2 RGS1 RGS2 CDC73 TROVE2 LOC105371665 MIR4426
GH01G192789 1.1 FANTOM5 dbSUPER 0.2 +73.7 73746 0.2 SOX13 FOXA2 ZNF644 CREM HOMEZ MIXL1 SOX5 GATAD2A HLF FOXA3 RGS1 RGS2 CDC73 TROVE2 LOC105371665 MIR4426
GH01G192739 0.7 ENCODE 0.3 +23.3 23258 0.2 SOX5 GATAD2A MAZ FOXA2 SAP130 FOXA3 ARID4B NFYC KLF16 CREB1 MIR4426 LOC105371665
GH01G192763 0.9 FANTOM5 ENCODE 0.2 +47.6 47645 0.7 CTCF MAFF JUND STAT3 CEBPB EHMT2 EP300 GABPA RGS13 LOC105371665 MIR4426
GH01G192722 0.3 FANTOM5 0.4 +6.3 6292 0.4 MIR4426 LOC105371665
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4426 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4426 Gene

Chromosome:
1
Start:
192,716,328 bp from pter
End:
192,716,390 bp from pter
Size:
63 bases
Orientation:
Plus strand

Genomic View for MIR4426 Gene

Genes around MIR4426 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4426 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4426 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4426 Gene

Proteins for MIR4426 Gene

Post-translational modifications for MIR4426 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4426 Gene

Domains & Families for MIR4426 Gene

Gene Families for MIR4426 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4426: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4426 Gene

Function for MIR4426 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4426 Gene

Localization for MIR4426 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4426 Gene

Pathways & Interactions for MIR4426 Gene

SuperPathways for MIR4426 Gene

No Data Available

Interacting Proteins for MIR4426 Gene

Gene Ontology (GO) - Biological Process for MIR4426 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4426 Gene

Drugs & Compounds for MIR4426 Gene

No Compound Related Data Available

Transcripts for MIR4426 Gene

mRNA/cDNA for MIR4426 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4426 Gene

No ASD Table

Relevant External Links for MIR4426 Gene

GeneLoc Exon Structure for
MIR4426
ECgene alternative splicing isoforms for
MIR4426

Expression for MIR4426 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4426 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4426 Gene:

MIR4426
genes like me logo Genes that share expression patterns with MIR4426: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4426 Gene

Orthologs for MIR4426 Gene

Evolution for MIR4426 Gene

ENSEMBL:
Gene Tree for MIR4426 (if available)
TreeFam:
Gene Tree for MIR4426 (if available)

No data available for Orthologs for MIR4426 Gene

Paralogs for MIR4426 Gene

No data available for Paralogs for MIR4426 Gene

Variants for MIR4426 Gene

Sequence variations from dbSNP and Humsavar for MIR4426 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1001490221 -- 192,715,464(+) CCTCT(A/G)TGAGT intron-variant, upstream-variant-2KB
rs1003092149 -- 192,716,695(+) AAAAA(A/G)AAAAA intron-variant, downstream-variant-500B
rs1003461203 -- 192,716,721(+) CAAAG(G/T)GATAA intron-variant, downstream-variant-500B
rs1003649833 -- 192,716,481(+) TAAGC(C/T)GGCTC intron-variant, downstream-variant-500B
rs1004999943 -- 192,716,597(+) ACAGA(C/T)ATTAT intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4426 Gene

Variant ID Type Subtype PubMed ID
esv2720078 CNV deletion 23290073
nsv466994 CNV loss 19166990
nsv522016 CNV gain 19592680
nsv548658 CNV loss 21841781
nsv548660 CNV gain 21841781
nsv572836 CNV gain 21841781
nsv946550 CNV duplication 23825009
nsv961777 CNV duplication 23825009
nsv974821 CNV duplication 23825009

Relevant External Links for MIR4426 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4426

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4426 Gene

Disorders for MIR4426 Gene

Relevant External Links for MIR4426

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4426

No disorders were found for MIR4426 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4426 Gene

Publications for MIR4426 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4426 Gene

Sources for MIR4426 Gene

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