Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR4425 Gene

Subcategory (RNA class) for MIR4425 Gene


Quality Score for this RNA gene is


Aliases for MIR4425 Gene

  • MicroRNA 4425 2 3 5
  • Hsa-Mir-4425 3

External Ids for MIR4425 Gene

Previous GeneCards Identifiers for MIR4425 Gene

  • GC01U903275
  • GC01P025351

Summaries for MIR4425 Gene

Entrez Gene Summary for MIR4425 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4425 Gene

MIR4425 (MicroRNA 4425) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4425 Gene

Genomics for MIR4425 Gene

Regulatory Elements for MIR4425 Gene

Enhancers for MIR4425 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F025017 1.5 FANTOM5 Ensembl ENCODE 0.8 +4.3 4298 20.8 HDGF PKNOX1 ARNT CREB3L1 WRNIP1 ZFP64 SIN3A YBX1 FEZF1 ZNF143 RUNX3 ENSG00000261025 ENSG00000231953 ENSG00000207302 RPL39P7 SYF2 LOC105376878 RSRP1 RHCE SDHDP6
GH01F025011 0.4 Ensembl 0.4 -12.0 -12003 0.2 SP3 GTF2E2 NRF1 MNT SP1 POLR2H ZFHX2 FOXK2 GLIS1 MLLT1 MIR4425 GC01M024955
GH01F025012 0.2 Ensembl 0.4 -11.0 -11003 1.4 HDGF PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 YY1 ZNF207 KLF13 SP3 MIR4425 GC01M024955
GH01F025006 0.2 Ensembl 0.3 -15.1 -15103 4.0 ATF1 PKNOX1 ARNT CREB3L1 SIN3A ZBTB40 RARA ZNF335 GLIS2 NCOA1 RUNX3 LOC105376878 MIR4425 GC01M024955
GH01F024996 0.9 Ensembl ENCODE 0.3 -26.0 -25997 1.4 HMBOX1 ZNF24 GRHL3 GC01M024955 MIR4425
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4425 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4425 Gene

25,023,503 bp from pter
25,023,586 bp from pter
84 bases
Plus strand

Genomic View for MIR4425 Gene

Genes around MIR4425 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4425 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4425 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4425 Gene

Proteins for MIR4425 Gene

Post-translational modifications for MIR4425 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4425 Gene

Domains & Families for MIR4425 Gene

Gene Families for MIR4425 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4425: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4425 Gene

Function for MIR4425 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4425 Gene

Localization for MIR4425 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4425 Gene

Pathways & Interactions for MIR4425 Gene

SuperPathways for MIR4425 Gene

No Data Available

Interacting Proteins for MIR4425 Gene

Gene Ontology (GO) - Biological Process for MIR4425 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4425 Gene

Transcripts for MIR4425 Gene

mRNA/cDNA for MIR4425 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4425 Gene

No ASD Table

Relevant External Links for MIR4425 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4425 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4425 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4425 Gene:

genes like me logo Genes that share expression patterns with MIR4425: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4425 Gene

Orthologs for MIR4425 Gene

Evolution for MIR4425 Gene

Gene Tree for MIR4425 (if available)
Gene Tree for MIR4425 (if available)

No data available for Orthologs for MIR4425 Gene

Paralogs for MIR4425 Gene

No data available for Paralogs for MIR4425 Gene

Variants for MIR4425 Gene

Sequence variations from dbSNP and Humsavar for MIR4425 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs112572656 -- 25,021,902(+) AGGTA(C/T)GCCTG upstream-variant-2KB
rs113883301 -- 25,023,537(+) CCAAC(A/G)GCTTT nc-transcript-variant
rs114903524 -- 25,023,007(+) AGGGA(C/T)GGGGC upstream-variant-2KB
rs115408542 -- 25,023,800(+) CTGTT(C/T)AGAGG downstream-variant-500B
rs116084333 -- 25,023,965(+) CTCTG(C/T)GTACT downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4425 Gene

Variant ID Type Subtype PubMed ID
dgv132n100 CNV gain 25217958
esv3576582 CNV gain 25503493

Relevant External Links for MIR4425 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4425 Gene

Disorders for MIR4425 Gene

Relevant External Links for MIR4425

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4425 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4425 Gene

Publications for MIR4425 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4425 Gene

Sources for MIR4425 Gene

Loading form....