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Aliases for MIR4419B Gene

Subcategory (RNA class) for MIR4419B Gene


Quality Score for this RNA gene is


Aliases for MIR4419B Gene

  • MicroRNA 4419b 2 3 5
  • Hsa-Mir-4419b 3

External Ids for MIR4419B Gene

Previous GeneCards Identifiers for MIR4419B Gene

  • GC12U901589
  • GC12P128732

Summaries for MIR4419B Gene

Entrez Gene Summary for MIR4419B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4419B Gene

MIR4419B (MicroRNA 4419b) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4419B Gene

Genomics for MIR4419B Gene

Genomic Location for MIR4419B Gene

128,244,506 bp from pter
128,244,573 bp from pter
68 bases
Plus strand

Genomic View for MIR4419B Gene

Genes around MIR4419B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4419B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4419B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4419B Gene

No data available for Regulatory Elements for MIR4419B Gene

Proteins for MIR4419B Gene

Post-translational modifications for MIR4419B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4419B Gene

Domains & Families for MIR4419B Gene

Gene Families for MIR4419B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4419B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4419B Gene

Function for MIR4419B Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4419B Gene

Localization for MIR4419B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4419B Gene

Pathways & Interactions for MIR4419B Gene

SuperPathways for MIR4419B Gene

No Data Available

Interacting Proteins for MIR4419B Gene

Gene Ontology (GO) - Biological Process for MIR4419B Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4419B Gene

Transcripts for MIR4419B Gene

mRNA/cDNA for MIR4419B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4419B Gene

No ASD Table

Relevant External Links for MIR4419B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4419B Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4419B Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4419B Gene

Orthologs for MIR4419B Gene

Evolution for MIR4419B Gene

Gene Tree for MIR4419B (if available)
Gene Tree for MIR4419B (if available)

No data available for Orthologs for MIR4419B Gene

Paralogs for MIR4419B Gene

No data available for Paralogs for MIR4419B Gene

Variants for MIR4419B Gene

Sequence variations from dbSNP and Humsavar for MIR4419B Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs10744372 -- 128,242,892(+) TTTTA(A/G)TCAAC upstream-variant-2KB
rs10847580 -- 128,243,236(+) CGGAC(G/T)ACACC upstream-variant-2KB
rs10847581 -- 128,244,606(+) ATTGC(A/G)CCACT downstream-variant-500B
rs114596354 -- 128,242,789(+) CTGCT(C/G)GTGGC upstream-variant-2KB
rs114695401 -- 128,244,575(+) GCCTC(A/G)GAGGC downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4419B Gene

Variant ID Type Subtype PubMed ID
dgv1573n100 CNV gain 25217958
esv3631133 CNV gain 21293372
nsv1160070 CNV duplication 26073780

Relevant External Links for MIR4419B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4419B Gene

Disorders for MIR4419B Gene

Relevant External Links for MIR4419B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4419B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4419B Gene

Publications for MIR4419B Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4419B Gene

Sources for MIR4419B Gene

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