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Aliases for MIR4418 Gene

Subcategory (RNA class) for MIR4418 Gene


Quality Score for this RNA gene is


Aliases for MIR4418 Gene

  • MicroRNA 4418 2 3 5
  • Hsa-Mir-4418 3

External Ids for MIR4418 Gene

Previous GeneCards Identifiers for MIR4418 Gene

  • GC01U903287
  • GC01P022593

Summaries for MIR4418 Gene

Entrez Gene Summary for MIR4418 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4418 Gene

MIR4418 (MicroRNA 4418) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4418 Gene

Genomics for MIR4418 Gene

Regulatory Elements for MIR4418 Gene

Enhancers for MIR4418 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F022261 0.7 Ensembl ENCODE 0.8 -3.7 -3667 1.3 RFX1 TCF7L2 MIR4418 LOC105376850
GH01F022264 0.5 ENCODE 0.8 -1.3 -1265 1.4 ZNF121 ZFP3 TEAD4 LINC00339 MIR4418 LOC105376850
GH01F022285 1.3 FANTOM5 ENCODE 0.3 +19.7 19666 1.1 ZNF766 GLIS2 ZNF263 NCOA1 REST SMARCA4 GLIS1 KDM1A BACH1 UBTF WNT4 MIR4418 LOC101060363
GH01F022273 0.8 ENCODE 0.4 +8.7 8665 2.6 CTCF HINFP ZNF2 RAD21 HIC1 GATA3 ZFHX2 ZNF366 ZNF143 SMC3 WNT4 LUZP1 MIR4418 LOC101060363
GH01F022259 0.7 ENCODE 0.4 -6.7 -6666 1.0 RFX1 BHLHE40 ZMYM3 NR3C1 ZBTB40 NR2F2 HDAC2 ZNF341 KLF9 KDM1A MIR4418 LOC105376850
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4418 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4418 Gene

22,266,239 bp from pter
22,266,300 bp from pter
62 bases
Plus strand

Genomic View for MIR4418 Gene

Genes around MIR4418 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4418 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4418 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4418 Gene

Proteins for MIR4418 Gene

Post-translational modifications for MIR4418 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4418 Gene

Domains & Families for MIR4418 Gene

Gene Families for MIR4418 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4418: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4418 Gene

Function for MIR4418 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4418 Gene

Localization for MIR4418 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4418 Gene

Pathways & Interactions for MIR4418 Gene

SuperPathways for MIR4418 Gene

No Data Available

Interacting Proteins for MIR4418 Gene

Gene Ontology (GO) - Biological Process for MIR4418 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4418 Gene

Transcripts for MIR4418 Gene

mRNA/cDNA for MIR4418 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4418 Gene

No ASD Table

Relevant External Links for MIR4418 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4418 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4418 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4418 Gene

Orthologs for MIR4418 Gene

Evolution for MIR4418 Gene

Gene Tree for MIR4418 (if available)
Gene Tree for MIR4418 (if available)

No data available for Orthologs for MIR4418 Gene

Paralogs for MIR4418 Gene

No data available for Paralogs for MIR4418 Gene

Variants for MIR4418 Gene

Sequence variations from dbSNP and Humsavar for MIR4418 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs10917193 -- 22,265,380(+) GTGTG(C/T)GCGCC upstream-variant-2KB
rs10917194 -- 22,265,382(+) gtgcg(C/T)gccag upstream-variant-2KB
rs111473610 -- 22,265,552(+) GCCTC(A/G)CGATT upstream-variant-2KB
rs113066374 -- 22,265,595(+) GTGTG(C/T)GTGTG upstream-variant-2KB
rs113688127 -- 22,265,255(+) GAAAA(G/T)CTCCT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4418 Gene

Variant ID Type Subtype PubMed ID
esv3585465 CNV loss 21293372
esv3585467 CNV loss 21293372
nsv516575 CNV loss 19592680

Relevant External Links for MIR4418 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4418 Gene

Disorders for MIR4418 Gene

Relevant External Links for MIR4418

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4418 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4418 Gene

Publications for MIR4418 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4418 Gene

Sources for MIR4418 Gene

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