Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR4323 Gene

Subcategory (RNA class) for MIR4323 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4323 Gene

  • MicroRNA 4323 2 3 5
  • Hsa-Mir-4323 3

External Ids for MIR4323 Gene

Previous GeneCards Identifiers for MIR4323 Gene

  • GC19U901401
  • GC19M042637

Summaries for MIR4323 Gene

Entrez Gene Summary for MIR4323 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4323 Gene

MIR4323 (MicroRNA 4323) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4323 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4323 Gene

Genomics for MIR4323 Gene

GeneHancer (GH) Regulatory Elements for MIR4323 Gene

Promoters and enhancers for MIR4323 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I042127 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 0.8 +2.6 2602 6 HDGF PKNOX1 ARID4B SIN3A IRF4 ZNF48 GLIS2 ARID2 ZNF207 ZNF143 POU2F2 LOC100505622 GRIK5 MEGF8 DEDD2 ARHGEF1 MIR4323 PIR55136
GH19I042140 Enhancer 0.8 ENCODE 0.4 -6.8 -6791 0.2 HDAC1 ELF3 ARID4B SIN3A ZNF48 ZSCAN9 ZBTB40 RARA ZNF766 ZNF143 POU2F2 DEDD2 ZNF526 MIR4323 ENSG00000259436
GH19I042143 Enhancer 0.7 ENCODE 0.4 -10.1 -10071 0.1 ELF3 AFF1 CAVIN1 E2F5 NCOA1 SIN3A MIER2 REST ZSCAN9 RARA ENSG00000259436 MIR4323 POU2F2
GH19I042150 Enhancer 0.5 FANTOM5 ENCODE 0.4 -17.1 -17126 0.3 ZNF398 ENSG00000259436 POU2F2 GRIK5 DEDD2 ZNF526 ATP1A3 MEGF8 TMEM145 MIR4323
GH19I042151 Enhancer 0.3 ENCODE 0.4 -17.8 -17790 0.5 POLR2A ENSG00000259436 GRIK5 POU2F2 DEDD2 ZNF526 ATP1A3 MEGF8 MIR4323
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4323 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4323 Gene

Genomic Locations for MIR4323 Gene
chr19:42,133,445-42,133,513
(GRCh38/hg38)
Size:
69 bases
Orientation:
Minus strand
chr19:42,637,597-42,637,665
(GRCh37/hg19)

Genomic View for MIR4323 Gene

Genes around MIR4323 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4323 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4323 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4323 Gene

Proteins for MIR4323 Gene

Post-translational modifications for MIR4323 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4323 Gene

Domains & Families for MIR4323 Gene

Gene Families for MIR4323 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4323: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4323 Gene

Function for MIR4323 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4323 Gene

Localization for MIR4323 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4323 Gene

Pathways & Interactions for MIR4323 Gene

SuperPathways for MIR4323 Gene

No Data Available

Interacting Proteins for MIR4323 Gene

Gene Ontology (GO) - Biological Process for MIR4323 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4323 Gene

Drugs & Compounds for MIR4323 Gene

No Compound Related Data Available

Transcripts for MIR4323 Gene

mRNA/cDNA for MIR4323 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4323 Gene

No ASD Table

Relevant External Links for MIR4323 Gene

GeneLoc Exon Structure for
MIR4323
ECgene alternative splicing isoforms for
MIR4323

Expression for MIR4323 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4323 Gene:

MIR4323
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4323 Gene

Orthologs for MIR4323 Gene

Evolution for MIR4323 Gene

ENSEMBL:
Gene Tree for MIR4323 (if available)
TreeFam:
Gene Tree for MIR4323 (if available)

No data available for Orthologs for MIR4323 Gene

Paralogs for MIR4323 Gene

No data available for Paralogs for MIR4323 Gene

Variants for MIR4323 Gene

Sequence variations from dbSNP and Humsavar for MIR4323 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1002467226 -- 42,134,980(-) A/G upstream_transcript_variant
rs1002516293 -- 42,134,851(-) C/T upstream_transcript_variant
rs1003468985 -- 42,134,063(-) G/A upstream_transcript_variant
rs1003523257 -- 42,133,629(-) C/G upstream_transcript_variant
rs1004188776 -- 42,133,386(-) T/A downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4323 Gene

Variant ID Type Subtype PubMed ID
nsv2496 CNV insertion 18451855
nsv520239 CNV loss 19592680
nsv522854 CNV gain 19592680

Additional Variant Information for MIR4323 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4323

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4323 Gene

Disorders for MIR4323 Gene

Additional Disease Information for MIR4323

No disorders were found for MIR4323 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4323 Gene

Publications for MIR4323 Gene

  1. MicroRNA 4323 induces human bladder smooth muscle cell proliferation under cyclic hydrodynamic pressure by activation of erk1/2 signaling pathway. (PMID: 27651435) Sun Y … Wang K (Experimental biology and medicine (Maywood, N.J.) 2017) 3 58
  2. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4323 Gene

Sources for MIR4323 Gene

Content
Loading form....