Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR4320 Gene

Subcategory (RNA class) for MIR4320 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4320 Gene

  • MicroRNA 4320 2 3 5
  • Hsa-Mir-4320 3

External Ids for MIR4320 Gene

Previous GeneCards Identifiers for MIR4320 Gene

  • GC18U900577
  • GC18M047652

Summaries for MIR4320 Gene

Entrez Gene Summary for MIR4320 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4320 Gene

MIR4320 (MicroRNA 4320) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4320 Gene

Genomics for MIR4320 Gene

Regulatory Elements for MIR4320 Gene

Enhancers for MIR4320 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH18F050127 0.9 Ensembl ENCODE 0.8 -2.3 -2338 3.4 GATAD2A PKNOX1 TFAP4 ZNF680 MTA2 WRNIP1 EBF1 TBX21 IKZF1 HNF4G MYO5B RPL17 MIR4320 GC18P050165
GH18F050099 1.4 FANTOM5 Ensembl ENCODE 0.3 +26.4 26440 1.4 PKNOX1 FEZF1 ZNF366 NFYB EED ETV6 FOS CREM ZNF639 MTA2 MYO5B MBD1 ENSG00000267591 MIR4320
GH18F050157 1.2 FANTOM5 Ensembl ENCODE 0.3 -33.8 -33802 5.7 RFX1 PKNOX1 TEAD4 DPF2 ZNF217 SREBF1 CTBP1 GATA3 PBX2 PRDM10 MYO5B RPL17 GC18P050165 MIR4320
GH18F050153 0.8 ENCODE 0.3 -28.2 -28240 1.6 CEBPG ZNF644 RAD21 YY1 POLR2A ZNF143 HNF4G MAFK CREM HOMEZ MYO5B LIPG GC18P050165 MIR4320
GH18F050143 0.6 ENCODE 0.3 -17.6 -17615 2.2 GATAD2A CTCF SAP130 ZBED1 CEBPB RAD21 CEBPA FOS MYO5B MIR4320 GC18P050165
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4320 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4320 Gene

Chromosome:
18
Start:
50,126,499 bp from pter
End:
50,126,563 bp from pter
Size:
65 bases
Orientation:
Minus strand

Genomic View for MIR4320 Gene

Genes around MIR4320 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4320 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4320 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4320 Gene

Proteins for MIR4320 Gene

Post-translational modifications for MIR4320 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4320 Gene

Domains & Families for MIR4320 Gene

Gene Families for MIR4320 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4320: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4320 Gene

Function for MIR4320 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4320 Gene

Localization for MIR4320 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4320 Gene

Pathways & Interactions for MIR4320 Gene

SuperPathways for MIR4320 Gene

No Data Available

Interacting Proteins for MIR4320 Gene

Gene Ontology (GO) - Biological Process for MIR4320 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4320 Gene

Transcripts for MIR4320 Gene

mRNA/cDNA for MIR4320 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4320 Gene

No ASD Table

Relevant External Links for MIR4320 Gene

GeneLoc Exon Structure for
MIR4320
ECgene alternative splicing isoforms for
MIR4320

Expression for MIR4320 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4320 Gene:

MIR4320
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4320 Gene

Orthologs for MIR4320 Gene

Evolution for MIR4320 Gene

ENSEMBL:
Gene Tree for MIR4320 (if available)
TreeFam:
Gene Tree for MIR4320 (if available)

No data available for Orthologs for MIR4320 Gene

Paralogs for MIR4320 Gene

No data available for Paralogs for MIR4320 Gene

Variants for MIR4320 Gene

Sequence variations from dbSNP and Humsavar for MIR4320 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type
rs111307129 -- 50,126,737(+) CTCCA(A/G)TGCAT intron-variant, upstream-variant-2KB
rs111724793 -- 50,127,047(+) TTCCA(A/G/T)CCTCA intron-variant, upstream-variant-2KB
rs113234101 -- 50,127,504(+) GGAGG(G/T)AAGGA intron-variant, upstream-variant-2KB
rs114028984 -- 50,127,773(+) GCTGT(G/T)TCTAG intron-variant, upstream-variant-2KB
rs115133998 -- 50,126,750(+) TCACA(C/T)CATCT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4320 Gene

Variant ID Type Subtype PubMed ID
nsv1057599 CNV gain 25217958
nsv1058554 CNV gain 25217958
nsv576867 CNV loss 21841781
nsv833650 CNV loss 17160897

Relevant External Links for MIR4320 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4320

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4320 Gene

Disorders for MIR4320 Gene

Relevant External Links for MIR4320

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4320

No disorders were found for MIR4320 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4320 Gene

Publications for MIR4320 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4320 Gene

Sources for MIR4320 Gene

Content
Loading form....