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Aliases for MIR432 Gene

Subcategory (RNA class) for MIR432 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR432 Gene

  • MicroRNA 432 2 3
  • Hsa-Mir-432 3
  • Mir-432 3
  • MIRN432 3

External Ids for MIR432 Gene

ORGUL Members for MIR432 Gene

Previous HGNC Symbols for MIR432 Gene

  • MIRN432

Previous GeneCards Identifiers for MIR432 Gene

  • GC14P100484
  • GC14P100860
  • GC14P101350
  • GC14P101075

Summaries for MIR432 Gene

Entrez Gene Summary for MIR432 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR432 Gene

MIR432 (MicroRNA 432) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR432 Gene

Genomics for MIR432 Gene

Genomic Location for MIR432 Gene

Chromosome:
14
Start:
100,884,483 bp from pter
End:
100,884,576 bp from pter
Size:
94 bases
Orientation:
Plus strand

Genomic View for MIR432 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR432 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR432 Gene

No data available for Regulatory Elements for MIR432 Gene

Proteins for MIR432 Gene

Post-translational modifications for MIR432 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR432 Gene

Domains & Families for MIR432 Gene

Gene Families for MIR432 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR432: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR432 Gene

Function for MIR432 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR432 Gene

Localization for MIR432 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR432 Gene

Pathways & Interactions for MIR432 Gene

SuperPathways for MIR432 Gene

No Data Available

Interacting Proteins for MIR432 Gene

Gene Ontology (GO) - Biological Process for MIR432 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR432 Gene

Drugs & Compounds for MIR432 Gene

No Compound Related Data Available

Transcripts for MIR432 Gene

mRNA/cDNA for MIR432 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR432 Gene

No ASD Table

Relevant External Links for MIR432 Gene

GeneLoc Exon Structure for
MIR432
ECgene alternative splicing isoforms for
MIR432

Expression for MIR432 Gene

mRNA expression in normal human tissues for MIR432 Gene

genes like me logo Genes that share expression patterns with MIR432: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR432 Gene

Orthologs for MIR432 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR432 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-432 36
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-432 36
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir432 36
  • 63 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-432 36
  • 100 (a)
OneToOne
Species with no ortholog for MIR432:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR432 Gene

ENSEMBL:
Gene Tree for MIR432 (if available)
TreeFam:
Gene Tree for MIR432 (if available)

Paralogs for MIR432 Gene

No data available for Paralogs for MIR432 Gene

Variants for MIR432 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR432 Gene

Variant ID Type Subtype PubMed ID
nsv902240 CNV Loss 21882294
nsv509549 CNV Insertion 20534489
nsv902241 CNV Loss 21882294

Relevant External Links for MIR432 Gene

HapMap Linkage Disequilibrium report
MIR432

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR432 Gene

Disorders for MIR432 Gene

Relevant External Links for MIR432

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR432
genes like me logo Genes that share disorders with MIR432: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR432 Gene

Publications for MIR432 Gene

  1. MicroRNA-432 contributes to dopamine cocktail and retinoic acid induced differentiation of human neuroblastoma cells by targeting NESTIN and RCOR1 genes. (PMID: 24657437) Das E. … Bhattacharyya N.P. (FEBS Lett. 2014) 67
  2. Heat shock factor 1 regulates hsa-miR-432 expression in human cervical cancer cell line. (PMID: 25280995) Das S. … Bhattacharyya N.P. (Biochem. Biophys. Res. Commun. 2014) 67
  3. [MiR432* regulate the replication of coxsackievirus A16 in rhabdomyosarcoma cells]. (PMID: 25272817) Yang Z. … Tien P. (Wei Sheng Wu Xue Bao 2014) 67
  4. Identification of miR-423 and miR-499 polymorphisms on affecting the risk of hepatocellular carcinoma in a large-scale population. (PMID: 24854593) Ma Y. … Wang J. (Genet Test Mol Biomarkers 2014) 67
  5. MicroRNA-mediated loss of ADAR1 in metastatic melanoma promotes tumor growth. (PMID: 23728176) Nemlich Y. … Markel G. (J. Clin. Invest. 2013) 67

Products for MIR432 Gene

Sources for MIR432 Gene

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