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Aliases for MIR4319 Gene

Subcategory (RNA class) for MIR4319 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4319 Gene

  • MicroRNA 4319 2 3 5
  • Hsa-Mir-4319 3

External Ids for MIR4319 Gene

Previous GeneCards Identifiers for MIR4319 Gene

  • GC18U900573
  • GC18M042550

Summaries for MIR4319 Gene

Entrez Gene Summary for MIR4319 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4319 Gene

MIR4319 (MicroRNA 4319) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4319 Gene

Genomics for MIR4319 Gene

Regulatory Elements for MIR4319 Gene

Enhancers for MIR4319 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH18F044937 1.9 Ensembl ENCODE 0.3 +31.4 31419 1.6 GFI1B ZNF140 FEZF1 REST ZIC2 ZNF843 OSR2 SMARCA4 GLIS1 KDM1A MIR4319 GC18M044779
GH18F044942 0.9 Ensembl ENCODE 0.3 +26.5 26452 1.8 TEAD4 HLF NR3C1 REST ZIC2 GATA3 BCL11A GLIS1 MAFK SETBP1 MIR4319 GC18M044779
GH18F044909 0.9 Ensembl ENCODE 0.2 +60.7 60708 0.7 MTA2 BHLHE40 ZBED1 CBFB JUNB EP300 RELA EED IKZF1 CREM MIR4319 GC18M044779
GH18F044886 0.9 Ensembl ENCODE 0.2 +82.5 82535 1.7 PKNOX1 MTA2 EBF1 TBX21 RELA OSR2 SMARCA4 EED IKZF1 NFYB GC18M044779 MIR4319
GH18F044895 0.9 Ensembl ENCODE 0.2 +74.6 74624 0.3 CTCF ZNF654 YY2 TRIM22 REST RAD21 YY1 KAT8 SMC3 KDM1A GC18M044779 MIR4319
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4319 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4319 Gene

Chromosome:
18
Start:
44,970,082 bp from pter
End:
44,970,166 bp from pter
Size:
85 bases
Orientation:
Minus strand

Genomic View for MIR4319 Gene

Genes around MIR4319 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4319 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4319 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4319 Gene

Proteins for MIR4319 Gene

Post-translational modifications for MIR4319 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4319 Gene

Domains & Families for MIR4319 Gene

Gene Families for MIR4319 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4319: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4319 Gene

Function for MIR4319 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4319 Gene

Localization for MIR4319 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4319 Gene

Pathways & Interactions for MIR4319 Gene

SuperPathways for MIR4319 Gene

No Data Available

Interacting Proteins for MIR4319 Gene

Gene Ontology (GO) - Biological Process for MIR4319 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4319 Gene

Transcripts for MIR4319 Gene

mRNA/cDNA for MIR4319 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4319 Gene

No ASD Table

Relevant External Links for MIR4319 Gene

GeneLoc Exon Structure for
MIR4319
ECgene alternative splicing isoforms for
MIR4319

Expression for MIR4319 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4319 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4319 Gene:

MIR4319
genes like me logo Genes that share expression patterns with MIR4319: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4319 Gene

Orthologs for MIR4319 Gene

Evolution for MIR4319 Gene

ENSEMBL:
Gene Tree for MIR4319 (if available)
TreeFam:
Gene Tree for MIR4319 (if available)

No data available for Orthologs for MIR4319 Gene

Paralogs for MIR4319 Gene

No data available for Paralogs for MIR4319 Gene

Variants for MIR4319 Gene

Sequence variations from dbSNP and Humsavar for MIR4319 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type
rs111260797 -- 44,970,542(+) TATAA(A/T)TACAA intron-variant, upstream-variant-2KB
rs112449274 -- 44,971,135(+) GTTTT(G/T)TGTCC intron-variant, upstream-variant-2KB
rs116551754 -- 44,969,673(+) TACAC(C/G)AAGTA intron-variant, downstream-variant-500B
rs138124094 -- 44,970,210(+) TCACC(A/G)AAAGG intron-variant, upstream-variant-2KB
rs139592197 -- 44,970,900(+) TTAGG(A/G)TACAT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4319 Gene

Variant ID Type Subtype PubMed ID
nsv833637 CNV gain 17160897

Relevant External Links for MIR4319 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4319

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4319 Gene

Disorders for MIR4319 Gene

Relevant External Links for MIR4319

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4319

No disorders were found for MIR4319 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4319 Gene

Publications for MIR4319 Gene

  1. A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants. (PMID: 22219177) Tao S. … Sun J. (Carcinogenesis 2012) 3 64
  2. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4319 Gene

Sources for MIR4319 Gene

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