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Aliases for MIR4315-2 Gene

Subcategory (RNA class) for MIR4315-2 Gene

miRNA

Quality Score for this RNA gene is

2

Aliases for MIR4315-2 Gene

  • MicroRNA 4315-2 2 3
  • Hsa-Mir-4315-2 3

External Ids for MIR4315-2 Gene

Previous GeneCards Identifiers for MIR4315-2 Gene

  • GC17U901507
  • GC17M043516
  • GC17M062818

Summaries for MIR4315-2 Gene

Entrez Gene Summary for MIR4315-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4315-2 Gene

MIR4315-2 (MicroRNA 4315-2) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR4315-2 include dandy-walker syndrome and juvenile xanthogranuloma.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4315-2 Gene

Genomics for MIR4315-2 Gene

Genomic Location for MIR4315-2 Gene

Start:
64,822,030 bp from pter
End:
64,822,102 bp from pter
Size:
73 bases
Orientation:
Minus strand

Genomic View for MIR4315-2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR4315-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4315-2 Gene

No data available for Regulatory Elements for MIR4315-2 Gene

Proteins for MIR4315-2 Gene

Post-translational modifications for MIR4315-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4315-2 Gene

Domains for MIR4315-2 Gene

Gene Families for MIR4315-2 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4315-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4315-2 Gene

Function for MIR4315-2 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR4315-2 Gene

Localization for MIR4315-2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MIR4315-2 Gene COMPARTMENTS Subcellular localization image for MIR4315-2 gene
Compartment Confidence
cytosol 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MIR4315-2 Gene

Pathways for MIR4315-2 Gene

SuperPathways for MIR4315-2 Gene

No Data Available

Interacting Proteins for MIR4315-2 Gene

Gene Ontology (GO) - Biological Process for MIR4315-2 Gene

None

No data available for Pathways by source for MIR4315-2 Gene

Transcripts for MIR4315-2 Gene

miRNA Products

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MIR4315-2
    • Block miRNA regulation of MIR4315-2 using miScript Target Protectors

    Inhibitory RNA Products

    • Predesigned siRNA for gene silencing in human,mouse,rat for MIR4315-2

    Primer Products

    Flow Cytometry Products

    Alternative Splicing Database (ASD) splice patterns (SP) for MIR4315-2 Gene

    No ASD Table

    Relevant External Links for MIR4315-2 Gene

    GeneLoc Exon Structure for
    MIR4315-2
    ECgene alternative splicing isoforms for
    MIR4315-2

    No data available for mRNA/cDNA for MIR4315-2 Gene

    Expression for MIR4315-2 Gene

    No Expression Related Data Available

    In Situ Assay Products

    No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR4315-2 Gene

    Orthologs for MIR4315-2 Gene

    No data available for Orthologs and Evolution for MIR4315-2 Gene

    Paralogs for MIR4315-2 Gene

    No data available for Paralogs for MIR4315-2 Gene

    Variants for MIR4315-2 Gene

    Structural Variations from Database of Genomic Variants (DGV) for MIR4315-2 Gene

    Variant ID Type Subtype PubMed ID
    nsv428342 CNV Gain 18775914
    dgv964e1 CNV Complex 17122850
    esv627 CNV CNV 17122850
    nsv511056 CNV Complex 20534489
    dgv965e1 CNV Complex 17122850
    dgv123e55 CNV Loss 17911159
    dgv966e1 CNV Complex 17122850
    dgv124e55 CNV Loss 17911159
    dgv967e1 CNV Complex 17122850
    nsv908686 CNV Gain 21882294
    dgv44n68 CNV Loss 17160897
    nsv469875 CNV Loss 16826518
    nsv471504 CNV Duplication 19718026
    dgv45n68 CNV Loss 17160897

    Relevant External Links for MIR4315-2 Gene

    HapMap Linkage Disequilibrium report
    MIR4315-2

    No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR4315-2 Gene

    Disorders for MIR4315-2 Gene

    MalaCards: The human disease database

    MalaCards: The human disease database. (2) Diseases for MIR4315-2 Gene including...

    Search for MIR4315-2 Gene in MalaCards »

    (3) University of Copenhagen DISEASES for MIR4315-2 Gene

    genes like me logo Genes that share disorders with MIR4315-2: view

    No data available for UniProtKB/Swiss-Prot for MIR4315-2 Gene

    Publications for MIR4315-2 Gene

    1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
    2. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3

    Products for MIR4315-2 Gene

    Sources for MIR4315-2 Gene

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