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Aliases for MIR4315-2 Gene

Subcategory (RNA class) for MIR4315-2 Gene

miRNA

Quality Score for this RNA gene is

2

Aliases for MIR4315-2 Gene

  • MicroRNA 4315-2 2 3
  • Hsa-Mir-4315-2 3

External Ids for MIR4315-2 Gene

Previous GeneCards Identifiers for MIR4315-2 Gene

  • GC17U901507
  • GC17M043516
  • GC17M062818

Summaries for MIR4315-2 Gene

Entrez Gene Summary for MIR4315-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4315-2 Gene

MIR4315-2 (MicroRNA 4315-2) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4315-2 Gene

Genomics for MIR4315-2 Gene

Genomic Location for MIR4315-2 Gene

Chromosome:
17
Start:
64,822,030 bp from pter
End:
64,822,102 bp from pter
Size:
73 bases
Orientation:
Minus strand

Genomic View for MIR4315-2 Gene

Genes around MIR4315-2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4315-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4315-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4315-2 Gene

No data available for Regulatory Elements for MIR4315-2 Gene

Proteins for MIR4315-2 Gene

Post-translational modifications for MIR4315-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4315-2 Gene

Domains & Families for MIR4315-2 Gene

Gene Families for MIR4315-2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4315-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4315-2 Gene

Function for MIR4315-2 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4315-2 Gene

Localization for MIR4315-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4315-2 Gene

Pathways & Interactions for MIR4315-2 Gene

SuperPathways for MIR4315-2 Gene

No Data Available

Interacting Proteins for MIR4315-2 Gene

Gene Ontology (GO) - Biological Process for MIR4315-2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4315-2 Gene

Transcripts for MIR4315-2 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4315-2 Gene

No ASD Table

Relevant External Links for MIR4315-2 Gene

GeneLoc Exon Structure for
MIR4315-2
ECgene alternative splicing isoforms for
MIR4315-2

No data available for mRNA/cDNA for MIR4315-2 Gene

Expression for MIR4315-2 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4315-2 Gene

Orthologs for MIR4315-2 Gene

No data available for Orthologs and Evolution for MIR4315-2 Gene

Paralogs for MIR4315-2 Gene

No data available for Paralogs for MIR4315-2 Gene

Variants for MIR4315-2 Gene

Sequence variations from dbSNP and Humsavar for MIR4315-2 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs112283912 -- 64,821,789(+) TGAGT(C/G)CTCAG nc-transcript-variant, downstream-variant-500B
rs113161625 -- 64,823,216(+) CCACA(C/T)CCAGC intron-variant, upstream-variant-2KB
rs113278458 -- 64,824,021(+) TGGGC(A/G)TGATG intron-variant, upstream-variant-2KB
rs138720972 -- 64,823,888(+) CTGGG(C/T)GCGGT intron-variant, upstream-variant-2KB
rs139939867 -- 64,821,923(+) TGGCC(A/G)TGTCC nc-transcript-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4315-2 Gene

Variant ID Type Subtype PubMed ID
nsv511056 OTHER complex 20534489
nsv471504 CNV gain 19718026
nsv469875 CNV loss 16826518
nsv428342 CNV gain 18775914
nsv1146669 OTHER inversion 26484159
nsv1120054 OTHER inversion 24896259
nsv1070407 CNV deletion 25765185
nsv1066765 CNV gain 25217958
esv2758691 CNV gain+loss 17122850
dgv45n68 CNV loss 17160897
dgv44n68 CNV loss 17160897
dgv3274n100 CNV gain 25217958
dgv1472n106 CNV deletion 24896259
dgv124e55 CNV loss 17911159
dgv123e55 CNV loss 17911159

Relevant External Links for MIR4315-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4315-2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4315-2 Gene

Disorders for MIR4315-2 Gene

Relevant External Links for MIR4315-2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4315-2

No disorders were found for MIR4315-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4315-2 Gene

Publications for MIR4315-2 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4315-2 Gene

Sources for MIR4315-2 Gene

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