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Aliases for MIR4314 Gene

Subcategory (RNA class) for MIR4314 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4314 Gene

  • MicroRNA 4314 2 3 5
  • Hsa-Mir-4314 3

External Ids for MIR4314 Gene

Previous GeneCards Identifiers for MIR4314 Gene

  • GC17U901510
  • GC17P007991

Summaries for MIR4314 Gene

Entrez Gene Summary for MIR4314 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4314 Gene

MIR4314 (MicroRNA 4314) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4314 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4314 Gene

Genomics for MIR4314 Gene

GeneHancer (GH) Regulatory Elements for MIR4314 Gene

Promoters and enhancers for MIR4314 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I008088 Promoter 0.9 EPDnew 550.8 -0.3 -320 0.1 PKNOX1 KLF1 ZNF687 MAZ KLF17 KLF4 GATA3 NFYB RCOR1 CHD2 ALOX12B MIR4314
GH17I008087 Enhancer 0.6 ENCODE 550.8 -0.1 -138 0.2 PKNOX1 KLF1 ZNF687 MAZ KLF17 KLF4 GATA3 NFYB RCOR1 CHD2 MIR4314 ALOX12B
GH17I008093 Enhancer 0.9 ENCODE 0.4 +6.0 5982 0.2 ZNF493 ZFP64 ZNF2 ZNF121 ZNF213 ZNF302 ZNF143 KLF7 ZNF202 SP3 DVL2 PFAS CTC1 CNTROB WRAP53 POLR2A SNORD10 ENSG00000265749 SNORA48 NLGN2
GH17I008109 Enhancer 1 Ensembl ENCODE 0.3 +21.8 21848 1.5 HDGF ATF1 RB1 NFIB SIN3A ZNF2 RAD21 ARID2 ZNF143 ATF7 ALOXE3 ALOX12B LOC107985075 ALOX15B SNORD118 TMEM107 TRAPPC1 CNTROB KCNAB3 PFAS
GH17I008105 Enhancer 0.7 ENCODE 0.4 +18.4 18358 1.1 KLF1 NFRKB ETV1 CEBPG ZFHX2 BRD9 ZNF600 L3MBTL2 ZEB2 EP300 ALOXE3 LOC107985075 ALOX15B SNORD118 TMEM107 KCNAB3 CNTROB TRAPPC1 PFAS BORCS6
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4314 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4314 Gene

Genomic Locations for MIR4314 Gene
chr17:8,088,056-8,088,147
(GRCh38/hg38)
Size:
92 bases
Orientation:
Plus strand
chr17:7,991,374-7,991,465
(GRCh37/hg19)

Genomic View for MIR4314 Gene

Genes around MIR4314 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4314 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4314 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4314 Gene

Proteins for MIR4314 Gene

Post-translational modifications for MIR4314 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4314 Gene

Domains & Families for MIR4314 Gene

Gene Families for MIR4314 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4314: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4314 Gene

Function for MIR4314 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4314 Gene

Localization for MIR4314 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4314 Gene

Pathways & Interactions for MIR4314 Gene

SuperPathways for MIR4314 Gene

No Data Available

Interacting Proteins for MIR4314 Gene

Gene Ontology (GO) - Biological Process for MIR4314 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4314 Gene

Drugs & Compounds for MIR4314 Gene

No Compound Related Data Available

Transcripts for MIR4314 Gene

mRNA/cDNA for MIR4314 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4314 Gene

No ASD Table

Relevant External Links for MIR4314 Gene

GeneLoc Exon Structure for
MIR4314
ECgene alternative splicing isoforms for
MIR4314

Expression for MIR4314 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4314 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4314 Gene:

MIR4314
genes like me logo Genes that share expression patterns with MIR4314: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4314 Gene

Orthologs for MIR4314 Gene

Evolution for MIR4314 Gene

ENSEMBL:
Gene Tree for MIR4314 (if available)
TreeFam:
Gene Tree for MIR4314 (if available)

No data available for Orthologs for MIR4314 Gene

Paralogs for MIR4314 Gene

No data available for Paralogs for MIR4314 Gene

Variants for MIR4314 Gene

Sequence variations from dbSNP and Humsavar for MIR4314 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs116492351 likely-benign, Congenital ichthyosiform erythroderma 8,087,600(+) C/A upstream_transcript_variant
rs117483056 uncertain-significance, Congenital ichthyosiform erythroderma 8,087,308(+) A/G upstream_transcript_variant
rs146260899 uncertain-significance, Congenital ichthyosiform erythroderma 8,087,299(+) C/T upstream_transcript_variant
rs149687727 uncertain-significance, Congenital ichthyosiform erythroderma 8,087,395(+) C/T upstream_transcript_variant
rs200663524 uncertain-significance, Congenital ichthyosiform erythroderma 8,086,067(+) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4314 Gene

Variant ID Type Subtype PubMed ID
nsv833352 CNV loss 17160897
nsv953825 CNV deletion 24416366

Additional Variant Information for MIR4314 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4314

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4314 Gene

Disorders for MIR4314 Gene

Additional Disease Information for MIR4314

No disorders were found for MIR4314 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4314 Gene

Publications for MIR4314 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4314 Gene

Sources for MIR4314 Gene

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