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Aliases for MIR4313 Gene

Subcategory (RNA class) for MIR4313 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4313 Gene

  • MicroRNA 4313 2 3 5
  • Hsa-Mir-4313 3

External Ids for MIR4313 Gene

Previous GeneCards Identifiers for MIR4313 Gene

  • GC15U901261
  • GC15M076054

Summaries for MIR4313 Gene

Entrez Gene Summary for MIR4313 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4313 Gene

MIR4313 (MicroRNA 4313) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4313 Gene

Genomics for MIR4313 Gene

Regulatory Elements for MIR4313 Gene

Enhancers for MIR4313 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15G075757 1.1 ENCODE 0.7 +3.6 3626 1.7 MLX CREB3L1 ARNT ZFP64 SIN3A DMAP1 ZNF2 YY1 ZNF766 ZNF207 ENSG00000261043 CSPG4 MIR4313 GC15P075748
GH15G075753 0.4 FANTOM5 0.4 +9.0 9036 0.2 ZNF146 ZFX MAN2C1 MIR4313 GC15P075748
GH15G075759 0.2 ENCODE 0.7 +2.4 2443 0.1 ENSG00000261043 MIR4313 GC15P075748
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4313 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4313 Gene

Chromosome:
15
Start:
75,762,215 bp from pter
End:
75,762,315 bp from pter
Size:
101 bases
Orientation:
Minus strand

Genomic View for MIR4313 Gene

Genes around MIR4313 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4313 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4313 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4313 Gene

ORGUL Member Location for MIR4313 Gene

ORGUL Member Location for MIR4313 gene

Proteins for MIR4313 Gene

Post-translational modifications for MIR4313 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4313 Gene

Domains & Families for MIR4313 Gene

Gene Families for MIR4313 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4313: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4313 Gene

Function for MIR4313 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4313 Gene

Localization for MIR4313 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4313 Gene

Pathways & Interactions for MIR4313 Gene

SuperPathways for MIR4313 Gene

No Data Available

Interacting Proteins for MIR4313 Gene

Gene Ontology (GO) - Biological Process for MIR4313 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4313 Gene

Transcripts for MIR4313 Gene

mRNA/cDNA for MIR4313 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4313 Gene

No ASD Table

Relevant External Links for MIR4313 Gene

GeneLoc Exon Structure for
MIR4313
ECgene alternative splicing isoforms for
MIR4313

Expression for MIR4313 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4313 Gene

mRNA differential expression in normal tissues according to GTEx for MIR4313 Gene

This gene is overexpressed in Testis (x17.7).

NURSA nuclear receptor signaling pathways regulating expression of MIR4313 Gene:

MIR4313
genes like me logo Genes that share expression patterns with MIR4313: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4313 Gene

Orthologs for MIR4313 Gene

Evolution for MIR4313 Gene

ENSEMBL:
Gene Tree for MIR4313 (if available)
TreeFam:
Gene Tree for MIR4313 (if available)

No data available for Orthologs for MIR4313 Gene

Paralogs for MIR4313 Gene

No data available for Paralogs for MIR4313 Gene

Variants for MIR4313 Gene

Sequence variations from dbSNP and Humsavar for MIR4313 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs1000705430 -- 75,763,492(+) GGGTC(C/T)GCAGT downstream-variant-500B, upstream-variant-2KB
rs1001227005 -- 75,763,710(+) TAAAA(A/T)ATTGA downstream-variant-500B, upstream-variant-2KB
rs1001827098 -- 75,762,686(+) TGCTG(A/G)GAGCT intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1002112539 -- 75,762,488(+) TCCAC(C/T)GCGCC intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1003170977 -- 75,761,733(+) TCTGC(A/G)CACCC intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4313 Gene

Variant ID Type Subtype PubMed ID
esv2749895 CNV deletion 23290073
esv3636929 CNV loss 21293372
nsv1116463 OTHER inversion 24896259
nsv527186 CNV loss 19592680
nsv974599 CNV duplication 23825009

Relevant External Links for MIR4313 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4313

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4313 Gene

Disorders for MIR4313 Gene

Relevant External Links for MIR4313

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4313

No disorders were found for MIR4313 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4313 Gene

Publications for MIR4313 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4313 Gene

Sources for MIR4313 Gene

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