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Aliases for MIR4312 Gene

Subcategory (RNA class) for MIR4312 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4312 Gene

  • MicroRNA 4312 2 3 5
  • Hsa-Mir-4312 3

External Ids for MIR4312 Gene

Previous GeneCards Identifiers for MIR4312 Gene

  • GC15U901218
  • GC15M069094

Summaries for MIR4312 Gene

Entrez Gene Summary for MIR4312 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4312 Gene

MIR4312 (MicroRNA 4312) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4312 Gene

Genomics for MIR4312 Gene

Regulatory Elements for MIR4312 Gene

Enhancers for MIR4312 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15F068800 0.2 Ensembl 0.8 +0.1 125 2.0 BCOR KLF1 ZMYM3 KLF17 ZIC2 YY1 ZNF316 ZNF366 ZBTB48 POLR2A CORO2B MIR4312 CARSP1
GH15F068799 0.7 Ensembl 0.8 +2.2 2225 0.2 ZEB2 ZNF2 ZNF843 ZNF366 ZNF692 ZNF600 FOS PRDM10 ZXDB ANP32A MIR4312 CARSP1
GH15F068786 0.9 FANTOM5 Ensembl ENCODE 0.4 +8.8 8767 12.5 HDGF PKNOX1 WRNIP1 FEZF1 GLI4 ZNF2 YY2 JUNB REST TBX21 ENSG00000259265 ENSG00000259410 ANP32A CORO2B PIAS1 MIR4312 CARSP1
GH15F068780 0.6 Ensembl ENCODE 0.3 +19.5 19539 3.2 SIN3A GLI4 FEZF1 DMAP1 ZNF2 ZNF48 YY1 GLIS2 ZNF207 ZNF416 PIAS1 ANP32A MIR4312 CARSP1
GH15F068784 0.2 ENCODE 0.3 +16.9 16929 0.2 GATA3 ANP32A MIR4312 CARSP1
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4312 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4312 Gene

Chromosome:
15
Start:
68,801,850 bp from pter
End:
68,801,925 bp from pter
Size:
76 bases
Orientation:
Minus strand

Genomic View for MIR4312 Gene

Genes around MIR4312 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4312 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4312 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4312 Gene

ORGUL Member Location for MIR4312 Gene

ORGUL Member Location for MIR4312 gene

Proteins for MIR4312 Gene

Post-translational modifications for MIR4312 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4312 Gene

Domains & Families for MIR4312 Gene

Gene Families for MIR4312 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4312: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4312 Gene

Function for MIR4312 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4312 Gene

Localization for MIR4312 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4312 Gene

Pathways & Interactions for MIR4312 Gene

SuperPathways for MIR4312 Gene

No Data Available

Interacting Proteins for MIR4312 Gene

Gene Ontology (GO) - Biological Process for MIR4312 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4312 Gene

Transcripts for MIR4312 Gene

mRNA/cDNA for MIR4312 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4312 Gene

No ASD Table

Relevant External Links for MIR4312 Gene

GeneLoc Exon Structure for
MIR4312
ECgene alternative splicing isoforms for
MIR4312

Expression for MIR4312 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4312 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4312 Gene:

MIR4312
genes like me logo Genes that share expression patterns with MIR4312: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4312 Gene

Orthologs for MIR4312 Gene

Evolution for MIR4312 Gene

ENSEMBL:
Gene Tree for MIR4312 (if available)
TreeFam:
Gene Tree for MIR4312 (if available)

No data available for Orthologs for MIR4312 Gene

Paralogs for MIR4312 Gene

No data available for Paralogs for MIR4312 Gene

Variants for MIR4312 Gene

Sequence variations from dbSNP and Humsavar for MIR4312 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs10689979 -- 68,801,819(+) TGAGT(-/CA)CACAC intron-variant, downstream-variant-500B
rs115780816 -- 68,801,868(+) GGACA(A/G)GAACA intron-variant, nc-transcript-variant
rs117870367 -- 68,802,480(+) CCAGT(C/T)TCTTA intron-variant, upstream-variant-2KB
rs12904108 -- 68,801,740(+) ATTAA(A/T)CTGTA intron-variant, downstream-variant-500B
rs13329267 -- 68,803,232(+) TGTTT(A/T)AAAAG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4312 Gene

Variant ID Type Subtype PubMed ID
nsv833046 CNV loss 17160897

Relevant External Links for MIR4312 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4312

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4312 Gene

Disorders for MIR4312 Gene

Relevant External Links for MIR4312

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4312

No disorders were found for MIR4312 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4312 Gene

Publications for MIR4312 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4312 Gene

Sources for MIR4312 Gene

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