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Aliases for MIR4309 Gene

Subcategory (RNA class) for MIR4309 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4309 Gene

  • MicroRNA 4309 2 3 5
  • Hsa-Mir-4309 3

External Ids for MIR4309 Gene

Previous GeneCards Identifiers for MIR4309 Gene

  • GC14U901127
  • GC14P083182
  • GC14P103005

Summaries for MIR4309 Gene

Entrez Gene Summary for MIR4309 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4309 Gene

MIR4309 (MicroRNA 4309) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4309 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4309 Gene

Genomics for MIR4309 Gene

GeneHancer (GH) Regulatory Elements for MIR4309 Gene

Promoters and enhancers for MIR4309 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I102538 Enhancer 1.4 Ensembl ENCODE dbSUPER 550.8 +0.2 214 2.9 PKNOX1 ATF1 ARID4B DMAP1 ZNF48 SLC30A9 ZNF766 GLIS2 SP5 NFYC MIR4309 RCOR1 TECPR2 CINP WDR20 LINC02323
GH14I102522 Enhancer 1.8 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -13.7 -13650 6 MLX YBX1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC GLIS1 RCOR2 RCOR1 WDR20 TECPR2 MOK ANKRD9 ZNF839 CDC42BPB TRAF3 RNU6-244P DYNC1H1
GH14I102535 Enhancer 0.8 ENCODE dbSUPER 0.8 -3.0 -3049 1.3 NFIL3 ZFHX2 SAP130 HLF ZNF223 ZMYM3 PRDM10 CEBPG PRDM4 CINP RCOR1 TECPR2 AMN MOK MIR4309 LOC105370680
GH14I102530 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -8.0 -8034 2.5 HDAC1 NFXL1 RFX5 HSF1 ZSCAN5C ZNF143 RCOR1 ATF7 ZHX1 SMARCA5 ANKRD9 RCOR1 TRAF3 MIR4309 LOC105370680
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4309 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4309 Gene

Genomic Locations for MIR4309 Gene
chr14:102,539,644-102,539,726
(GRCh38/hg38)
Size:
83 bases
Orientation:
Plus strand
chr14:103,005,981-103,006,063
(GRCh37/hg19)

Genomic View for MIR4309 Gene

Genes around MIR4309 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4309 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4309 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4309 Gene

Proteins for MIR4309 Gene

Post-translational modifications for MIR4309 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4309 Gene

Domains & Families for MIR4309 Gene

Gene Families for MIR4309 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4309: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4309 Gene

Function for MIR4309 Gene

Phenotypes From GWAS Catalog for MIR4309 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4309 Gene

Localization for MIR4309 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4309 Gene

Pathways & Interactions for MIR4309 Gene

SuperPathways for MIR4309 Gene

No Data Available

Interacting Proteins for MIR4309 Gene

Gene Ontology (GO) - Biological Process for MIR4309 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4309 Gene

Drugs & Compounds for MIR4309 Gene

No Compound Related Data Available

Transcripts for MIR4309 Gene

mRNA/cDNA for MIR4309 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4309 Gene

No ASD Table

Relevant External Links for MIR4309 Gene

GeneLoc Exon Structure for
MIR4309
ECgene alternative splicing isoforms for
MIR4309

Expression for MIR4309 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4309 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4309 Gene:

MIR4309
genes like me logo Genes that share expression patterns with MIR4309: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4309 Gene

Orthologs for MIR4309 Gene

Evolution for MIR4309 Gene

ENSEMBL:
Gene Tree for MIR4309 (if available)
TreeFam:
Gene Tree for MIR4309 (if available)

No data available for Orthologs for MIR4309 Gene

Paralogs for MIR4309 Gene

No data available for Paralogs for MIR4309 Gene

Variants for MIR4309 Gene

Sequence variations from dbSNP and Humsavar for MIR4309 Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs1000513673 -- 102,539,680(+) G/C non_coding_transcript_variant
rs1000986224 -- 102,539,224(+) G/A upstream_transcript_variant
rs1001333668 -- 102,539,470(+) C/T upstream_transcript_variant
rs1002050242 -- 102,539,130(+) C/T upstream_transcript_variant
rs1002102252 -- 102,538,755(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4309 Gene

Variant ID Type Subtype PubMed ID
dgv263n27 CNV gain 19166990
nsv1046125 CNV gain 25217958
nsv1049544 CNV gain 25217958
nsv470671 CNV gain 18288195
nsv565948 CNV gain 21841781
nsv832880 CNV loss 17160897
nsv952255 CNV deletion 24416366

Additional Variant Information for MIR4309 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4309

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4309 Gene

Disorders for MIR4309 Gene

Additional Disease Information for MIR4309

No disorders were found for MIR4309 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4309 Gene

Publications for MIR4309 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4309 Gene

Sources for MIR4309 Gene

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