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Aliases for MIR4309 Gene

Subcategory (RNA class) for MIR4309 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4309 Gene

  • MicroRNA 4309 2 3 5
  • Hsa-Mir-4309 3

External Ids for MIR4309 Gene

Previous GeneCards Identifiers for MIR4309 Gene

  • GC14U901127
  • GC14P083182
  • GC14P103005

Summaries for MIR4309 Gene

Entrez Gene Summary for MIR4309 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4309 Gene

MIR4309 (MicroRNA 4309) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4309 Gene

Genomics for MIR4309 Gene

Regulatory Elements for MIR4309 Gene

Enhancers for MIR4309 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR4309 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4309 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MIR4309 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4309 Gene

Chromosome:
14
Start:
102,539,644 bp from pter
End:
102,539,726 bp from pter
Size:
83 bases
Orientation:
Plus strand

Genomic View for MIR4309 Gene

Genes around MIR4309 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4309 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4309 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4309 Gene

Proteins for MIR4309 Gene

Post-translational modifications for MIR4309 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4309 Gene

Domains & Families for MIR4309 Gene

Gene Families for MIR4309 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4309: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4309 Gene

Function for MIR4309 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4309 Gene

Localization for MIR4309 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4309 Gene

Pathways & Interactions for MIR4309 Gene

SuperPathways for MIR4309 Gene

No Data Available

Interacting Proteins for MIR4309 Gene

Gene Ontology (GO) - Biological Process for MIR4309 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4309 Gene

Drugs & Compounds for MIR4309 Gene

No Compound Related Data Available

Transcripts for MIR4309 Gene

mRNA/cDNA for MIR4309 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4309 Gene

No ASD Table

Relevant External Links for MIR4309 Gene

GeneLoc Exon Structure for
MIR4309
ECgene alternative splicing isoforms for
MIR4309

Expression for MIR4309 Gene

mRNA expression in normal human tissues for MIR4309 Gene

genes like me logo Genes that share expression patterns with MIR4309: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR4309 Gene

Orthologs for MIR4309 Gene

Evolution for MIR4309 Gene

ENSEMBL:
Gene Tree for MIR4309 (if available)
TreeFam:
Gene Tree for MIR4309 (if available)

No data available for Orthologs for MIR4309 Gene

Paralogs for MIR4309 Gene

No data available for Paralogs for MIR4309 Gene

Variants for MIR4309 Gene

Sequence variations from dbSNP and Humsavar for MIR4309 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs7141592 -- 102,539,905(+) AGCAC(C/T)TTTGG downstream-variant-500B
rs7142031 -- 102,539,962(+) AGCAA(A/G)GGAGC downstream-variant-500B
rs2146428 -- 102,539,330(+) CCAGG(C/T)TGGGG upstream-variant-2KB
rs10747306 -- 102,538,605(+) CTCTG(C/T)GCTGT upstream-variant-2KB
rs12879262 -- 102,539,710(+) CTGCG(C/G)TTTGA nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4309 Gene

Variant ID Type Subtype PubMed ID
nsv832880 CNV Loss 17160897
nsv470671 CNV Gain 18288195
dgv263n27 CNV Gain 19166990
nsv902255 CNV Loss 21882294

Relevant External Links for MIR4309 Gene

HapMap Linkage Disequilibrium report
MIR4309

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4309 Gene

Disorders for MIR4309 Gene

Relevant External Links for MIR4309

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4309

No disorders were found for MIR4309 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4309 Gene

Publications for MIR4309 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 67
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3

Products for MIR4309 Gene

Sources for MIR4309 Gene

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