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Aliases for MIR4304 Gene

Subcategory (RNA class) for MIR4304 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4304 Gene

  • MicroRNA 4304 2 3 5
  • Hsa-Mir-4304 3

External Ids for MIR4304 Gene

Previous GeneCards Identifiers for MIR4304 Gene

  • GC12U901385
  • GC12M123495

Summaries for MIR4304 Gene

Entrez Gene Summary for MIR4304 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4304 Gene

MIR4304 (MicroRNA 4304) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4304 Gene

Genomics for MIR4304 Gene

Regulatory Elements for MIR4304 Gene

Enhancers for MIR4304 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12G122978 1.4 Ensembl ENCODE 0.3 +27.1 27124 9.7 HNRNPUL1 HDGF FOXA2 PKNOX1 CREB3L1 MLX AGO1 ZFP64 SIN3A ARID4B CDK2AP1 MPHOSPH9 PITPNM2 ENSG00000256092 ABCB9 MIR4304
GH12G122993 0.8 ENCODE 0.4 +16.9 16871 1.5 TBL1XR1 BMI1 RAD21 ZNF121 GATA2 FOS RELB ETV6 IKZF2 ZNF263 PITPNM2 ABCB9 MIR4304
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4304 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4304 Gene

Chromosome:
12
Start:
123,010,667 bp from pter
End:
123,010,728 bp from pter
Size:
62 bases
Orientation:
Minus strand

Genomic View for MIR4304 Gene

Genes around MIR4304 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4304 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4304 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4304 Gene

ORGUL Member Location for MIR4304 Gene

ORGUL Member Location for MIR4304 gene

Proteins for MIR4304 Gene

Post-translational modifications for MIR4304 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4304 Gene

Domains & Families for MIR4304 Gene

Gene Families for MIR4304 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4304: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4304 Gene

Function for MIR4304 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4304 Gene

Localization for MIR4304 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4304 Gene

Pathways & Interactions for MIR4304 Gene

SuperPathways for MIR4304 Gene

No Data Available

Interacting Proteins for MIR4304 Gene

Gene Ontology (GO) - Biological Process for MIR4304 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4304 Gene

Transcripts for MIR4304 Gene

mRNA/cDNA for MIR4304 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4304 Gene

No ASD Table

Relevant External Links for MIR4304 Gene

GeneLoc Exon Structure for
MIR4304
ECgene alternative splicing isoforms for
MIR4304

Expression for MIR4304 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4304 Gene:

MIR4304
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4304 Gene

Orthologs for MIR4304 Gene

Evolution for MIR4304 Gene

ENSEMBL:
Gene Tree for MIR4304 (if available)
TreeFam:
Gene Tree for MIR4304 (if available)

No data available for Orthologs for MIR4304 Gene

Paralogs for MIR4304 Gene

No data available for Paralogs for MIR4304 Gene

Variants for MIR4304 Gene

Sequence variations from dbSNP and Humsavar for MIR4304 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs1001007389 -- 123,012,059(+) CTGCA(C/G)TGGCC intron-variant, upstream-variant-2KB
rs1002273571 -- 123,011,756(+) TGCCG(A/G)CAAGC intron-variant, upstream-variant-2KB
rs1003277394 -- 123,010,480(+) CACTG(A/G)GGAGA intron-variant, downstream-variant-500B
rs1003770186 -- 123,010,674(+) AGAAG(A/G)ATGGC intron-variant, nc-transcript-variant
rs1005491756 -- 123,011,535(+) TGAAC(A/G)CAGTG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4304 Gene

Variant ID Type Subtype PubMed ID
dgv22n68 CNV loss 17160897
nsv455732 CNV loss 19166990
nsv517200 CNV loss 19592680
nsv560492 CNV loss 21841781
nsv560494 CNV loss 21841781

Relevant External Links for MIR4304 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4304

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4304 Gene

Disorders for MIR4304 Gene

Relevant External Links for MIR4304

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4304

No disorders were found for MIR4304 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4304 Gene

Publications for MIR4304 Gene

  1. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. (PMID: 23974872) Ripke S. … Sullivan P.F. (Nat. Genet. 2013) 3 64
  2. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4304 Gene

Sources for MIR4304 Gene

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