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Aliases for MIR4300 Gene

Subcategory (RNA class) for MIR4300 Gene


Quality Score for this RNA gene is


Aliases for MIR4300 Gene

  • MicroRNA 4300 2 3 5
  • Hsa-Mir-4300 3

External Ids for MIR4300 Gene

Previous GeneCards Identifiers for MIR4300 Gene

  • GC11U901675
  • GC11M081601

Summaries for MIR4300 Gene

Entrez Gene Summary for MIR4300 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4300 Gene

MIR4300 (MicroRNA 4300) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4300 Gene

Genomics for MIR4300 Gene

Regulatory Elements for MIR4300 Gene

Enhancers for MIR4300 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11F081874 0.4 ENCODE 0.3 +16.0 15983 0.2 PKNOX1 SMARCA4 POLR2A REST MIR4300 ENSG00000270701
GH11F081868 0.7 Ensembl ENCODE 0.3 +20.7 20745 2.6 TBL1XR1 MAX BMI1 ZBTB40 RELA CBX5 EED ZNF207 ETV6 CREM MIR4300 ENSG00000270701
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4300 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4300 Gene

81,890,741 bp from pter
81,890,836 bp from pter
96 bases
Minus strand

Genomic View for MIR4300 Gene

Genes around MIR4300 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4300 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4300 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4300 Gene

ORGUL Member Location for MIR4300 Gene

ORGUL Member Location for MIR4300 gene

Proteins for MIR4300 Gene

Post-translational modifications for MIR4300 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4300 Gene

Domains & Families for MIR4300 Gene

Gene Families for MIR4300 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4300: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4300 Gene

Function for MIR4300 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4300 Gene

Localization for MIR4300 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4300 Gene

Pathways & Interactions for MIR4300 Gene

SuperPathways for MIR4300 Gene

No Data Available

Interacting Proteins for MIR4300 Gene

Gene Ontology (GO) - Biological Process for MIR4300 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4300 Gene

Transcripts for MIR4300 Gene

mRNA/cDNA for MIR4300 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4300 Gene

No ASD Table

Relevant External Links for MIR4300 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4300 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4300 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4300 Gene:

genes like me logo Genes that share expression patterns with MIR4300: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4300 Gene

Orthologs for MIR4300 Gene

Evolution for MIR4300 Gene

Gene Tree for MIR4300 (if available)
Gene Tree for MIR4300 (if available)

No data available for Orthologs for MIR4300 Gene

Paralogs for MIR4300 Gene

No data available for Paralogs for MIR4300 Gene

Variants for MIR4300 Gene

Sequence variations from dbSNP and Humsavar for MIR4300 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs11232917 -- 81,891,000(+) AATTT(C/T)CTGAA intron-variant, upstream-variant-2KB
rs11232918 -- 81,891,455(+) TCTCA(C/T)TTGTG intron-variant, upstream-variant-2KB
rs114288908 -- 81,892,513(+) ATGTG(A/C)ATATT intron-variant, upstream-variant-2KB
rs114845518 -- 81,892,527(+) CATAA(C/T)TGTTG intron-variant, upstream-variant-2KB
rs115105796 -- 81,891,349(+) AACTG(A/C)TTCTT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4300 Gene

Variant ID Type Subtype PubMed ID
dgv53e55 CNV loss 17911159
esv2664646 CNV deletion 23128226
esv2759843 CNV loss 17122850
esv3579768 CNV loss 25503493
esv3626971 CNV loss 21293372
esv3626972 CNV loss 21293372
nsv1037497 CNV gain 25217958
nsv1048620 CNV gain 25217958
nsv1054416 CNV gain 25217958
nsv437132 CNV loss 16327808
nsv468759 CNV gain 19166990
nsv555488 CNV loss 21841781
nsv555553 CNV gain 21841781
nsv555558 CNV gain 21841781

Relevant External Links for MIR4300 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4300 Gene

Disorders for MIR4300 Gene

Relevant External Links for MIR4300

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4300 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4300 Gene

Publications for MIR4300 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4300 Gene

Sources for MIR4300 Gene

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