Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR4298 Gene

Subcategory (RNA class) for MIR4298 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4298 Gene

  • MicroRNA 4298 2 3 5
  • Hsa-Mir-4298 3

External Ids for MIR4298 Gene

Previous GeneCards Identifiers for MIR4298 Gene

  • GC11U901684

Summaries for MIR4298 Gene

Entrez Gene Summary for MIR4298 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4298 Gene

MIR4298 (MicroRNA 4298) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4298 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4298 Gene

Genomics for MIR4298 Gene

GeneHancer (GH) Regulatory Elements for MIR4298 Gene

Promoters and enhancers for MIR4298 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11I001862 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE dbSUPER 0.8 -4.4 -4412 2.6 HDGF GLI4 GLIS2 ZNF143 FOS RXRA ZBTB11 REST ZNF398 NR2F2 ENSG00000249086 GC11P001865 LSP1 TNNT3 MIR4298 GC11P001831
GH11I001856 Enhancer 0.2 Ensembl 0.8 +2.6 2635 0.2 MIR4298 LSP1 GC11P001831
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4298 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4298 Gene

Genomic Locations for MIR4298 Gene
chr11:1,859,464-1,859,536
(GRCh38/hg38)
Size:
73 bases
Orientation:
Minus strand
chr11:1,880,694-1,880,766
(GRCh37/hg19)

Genomic View for MIR4298 Gene

Genes around MIR4298 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4298 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4298 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4298 Gene

Proteins for MIR4298 Gene

Post-translational modifications for MIR4298 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4298 Gene

Domains & Families for MIR4298 Gene

Gene Families for MIR4298 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4298: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4298 Gene

Function for MIR4298 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4298 Gene

Localization for MIR4298 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4298 Gene

Pathways & Interactions for MIR4298 Gene

SuperPathways for MIR4298 Gene

No Data Available

Interacting Proteins for MIR4298 Gene

Gene Ontology (GO) - Biological Process for MIR4298 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4298 Gene

Drugs & Compounds for MIR4298 Gene

No Compound Related Data Available

Transcripts for MIR4298 Gene

mRNA/cDNA for MIR4298 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4298 Gene

No ASD Table

Relevant External Links for MIR4298 Gene

GeneLoc Exon Structure for
MIR4298
ECgene alternative splicing isoforms for
MIR4298

Expression for MIR4298 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4298 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4298 Gene:

MIR4298
genes like me logo Genes that share expression patterns with MIR4298: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4298 Gene

Orthologs for MIR4298 Gene

Evolution for MIR4298 Gene

ENSEMBL:
Gene Tree for MIR4298 (if available)
TreeFam:
Gene Tree for MIR4298 (if available)

No data available for Orthologs for MIR4298 Gene

Paralogs for MIR4298 Gene

No data available for Paralogs for MIR4298 Gene

Variants for MIR4298 Gene

Sequence variations from dbSNP and Humsavar for MIR4298 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000366717 -- 1,860,763(-) T/C upstream_transcript_variant
rs1002522697 -- 1,860,145(-) C/T upstream_transcript_variant
rs1002999128 -- 1,859,078(-) C/A/T downstream_transcript_variant
rs1005934356 -- 1,860,322(-) G/T upstream_transcript_variant
rs1006939816 -- 1,861,203(-) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4298 Gene

Variant ID Type Subtype PubMed ID
dgv1565n54 CNV loss 21841781
esv29980 CNV loss 17803354
nsv1047474 CNV gain 25217958
nsv1159792 CNV deletion 26073780
nsv467645 CNV gain 19166990
nsv467647 CNV loss 19166990
nsv467648 CNV loss 19166990
nsv469926 CNV loss 18288195
nsv522320 CNV loss 19592680
nsv553047 CNV gain 21841781
nsv553050 CNV loss 21841781
nsv553053 CNV loss 21841781

Additional Variant Information for MIR4298 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4298

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4298 Gene

Disorders for MIR4298 Gene

Additional Disease Information for MIR4298

No disorders were found for MIR4298 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4298 Gene

Publications for MIR4298 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4298 Gene

Sources for MIR4298 Gene

Content
Loading form....