Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR4298 Gene

Subcategory (RNA class) for MIR4298 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4298 Gene

  • MicroRNA 4298 2 3 5
  • Hsa-Mir-4298 3

External Ids for MIR4298 Gene

Previous GeneCards Identifiers for MIR4298 Gene

  • GC11U901684

Summaries for MIR4298 Gene

Entrez Gene Summary for MIR4298 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4298 Gene

MIR4298 (MicroRNA 4298) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4298 Gene

Genomics for MIR4298 Gene

Regulatory Elements for MIR4298 Gene

Enhancers for MIR4298 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11F001862 1.1 Ensembl ENCODE 0.8 -4.5 -4465 2.8 CHD4 MAX GLI4 YBX1 HIC1 GLIS2 ZNF366 POLR2A ZNF600 FOS TNNT3 MIR4298 ENSG00000249086
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4298 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4298 Gene

Chromosome:
11
Start:
1,859,464 bp from pter
End:
1,859,536 bp from pter
Size:
73 bases
Orientation:
Minus strand

Genomic View for MIR4298 Gene

Genes around MIR4298 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4298 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4298 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4298 Gene

Proteins for MIR4298 Gene

Post-translational modifications for MIR4298 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4298 Gene

Domains & Families for MIR4298 Gene

Gene Families for MIR4298 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4298: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4298 Gene

Function for MIR4298 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4298 Gene

Localization for MIR4298 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4298 Gene

Pathways & Interactions for MIR4298 Gene

SuperPathways for MIR4298 Gene

No Data Available

Interacting Proteins for MIR4298 Gene

Gene Ontology (GO) - Biological Process for MIR4298 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4298 Gene

Transcripts for MIR4298 Gene

mRNA/cDNA for MIR4298 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4298 Gene

No ASD Table

Relevant External Links for MIR4298 Gene

GeneLoc Exon Structure for
MIR4298
ECgene alternative splicing isoforms for
MIR4298

Expression for MIR4298 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4298 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4298 Gene:

MIR4298
genes like me logo Genes that share expression patterns with MIR4298: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4298 Gene

Orthologs for MIR4298 Gene

Evolution for MIR4298 Gene

ENSEMBL:
Gene Tree for MIR4298 (if available)
TreeFam:
Gene Tree for MIR4298 (if available)

No data available for Orthologs for MIR4298 Gene

Paralogs for MIR4298 Gene

No data available for Paralogs for MIR4298 Gene

Variants for MIR4298 Gene

Sequence variations from dbSNP and Humsavar for MIR4298 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs11041524 -- 1,860,309(+) GATGG(A/G)TGGAT intron-variant, upstream-variant-2KB
rs11041526 -- 1,860,758(+) GATGA(A/G)TGGAT intron-variant, upstream-variant-2KB
rs11041527 -- 1,860,862(+) GATGA(G/T)TGGAT intron-variant, upstream-variant-2KB
rs11041528 -- 1,860,870(+) GATGG(C/G)TGGAA intron-variant, upstream-variant-2KB
rs112839927 -- 1,859,534(+) ACCTC(A/C)CCTCA intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4298 Gene

Variant ID Type Subtype PubMed ID
nsv553053 CNV loss 21841781
nsv553050 CNV loss 21841781
nsv553047 CNV gain 21841781
nsv522320 CNV loss 19592680
nsv469926 CNV loss 18288195
nsv467648 CNV loss 19166990
nsv467647 CNV loss 19166990
nsv467645 CNV gain 19166990
nsv1159792 CNV deletion 26073780
nsv1047474 CNV gain 25217958
esv29980 CNV loss 17803354
dgv1565n54 CNV loss 21841781

Relevant External Links for MIR4298 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4298

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4298 Gene

Disorders for MIR4298 Gene

Relevant External Links for MIR4298

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4298

No disorders were found for MIR4298 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4298 Gene

Publications for MIR4298 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4298 Gene

Sources for MIR4298 Gene

Content
Loading form....