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Aliases for MIR4296 Gene

Subcategory (RNA class) for MIR4296 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4296 Gene

  • MicroRNA 4296 2 3 5
  • Hsa-Mir-4296 3

External Ids for MIR4296 Gene

Previous GeneCards Identifiers for MIR4296 Gene

  • GC10U901392
  • GC10M126721

Summaries for MIR4296 Gene

Entrez Gene Summary for MIR4296 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4296 Gene

MIR4296 (MicroRNA 4296) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4296 Gene

Genomics for MIR4296 Gene

Regulatory Elements for MIR4296 Gene

Enhancers for MIR4296 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10F125034 1 Ensembl ENCODE 0.8 -4.4 -4423 5.5 TBP PKNOX1 ZNF76 FEZF1 RAD21 RFX5 SCRT2 RCOR1 FOS CEBPB CTBP2 MIR4296
GH10F125028 0.2 ENCODE 0.8 +4.3 4300 0.7 ZBTB8A WT1 ENSG00000226899 CTBP2 MIR4296 LOC105378540
GH10F125029 0.2 ENCODE 0.8 +3.2 3194 0.5 ZNF362 GATA3 RFX1 BHLHE40 FOS ZBTB33 MAFK CTBP2 MIR4296 LOC105378540
GH10F125030 0.2 ENCODE 0.8 +2.8 2839 0.1 GATA3 RFX1 MIR4296 LOC105378540
GH10F125042 1.2 Ensembl ENCODE 0.4 -9.5 -9531 0.8 POLR2A GLIS1 ZIC2 MIR4296 CTBP2
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4296 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4296 Gene

Chromosome:
10
Start:
125,032,783 bp from pter
End:
125,032,870 bp from pter
Size:
88 bases
Orientation:
Minus strand

Genomic View for MIR4296 Gene

Genes around MIR4296 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4296 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4296 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4296 Gene

Proteins for MIR4296 Gene

Post-translational modifications for MIR4296 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4296 Gene

Domains & Families for MIR4296 Gene

Gene Families for MIR4296 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4296: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4296 Gene

Function for MIR4296 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4296 Gene

Localization for MIR4296 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4296 Gene

Pathways & Interactions for MIR4296 Gene

SuperPathways for MIR4296 Gene

No Data Available

Interacting Proteins for MIR4296 Gene

Gene Ontology (GO) - Biological Process for MIR4296 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4296 Gene

Transcripts for MIR4296 Gene

mRNA/cDNA for MIR4296 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4296 Gene

No ASD Table

Relevant External Links for MIR4296 Gene

GeneLoc Exon Structure for
MIR4296
ECgene alternative splicing isoforms for
MIR4296

Expression for MIR4296 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4296 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4296 Gene:

MIR4296
genes like me logo Genes that share expression patterns with MIR4296: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4296 Gene

Orthologs for MIR4296 Gene

Evolution for MIR4296 Gene

ENSEMBL:
Gene Tree for MIR4296 (if available)
TreeFam:
Gene Tree for MIR4296 (if available)

No data available for Orthologs for MIR4296 Gene

Paralogs for MIR4296 Gene

No data available for Paralogs for MIR4296 Gene

Variants for MIR4296 Gene

Sequence variations from dbSNP and Humsavar for MIR4296 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs1077497 -- 125,034,564(+) CAACA(C/T)TATGA intron-variant, upstream-variant-2KB
rs10901851 -- 125,034,081(+) TGAGT(A/C)TGAAG intron-variant, upstream-variant-2KB
rs112674547 -- 125,033,462(+) AGCTT(A/T)AACAC intron-variant, upstream-variant-2KB
rs112983737 -- 125,033,050(+) ACTCT(C/T)AGCCT intron-variant, upstream-variant-2KB
rs113113628 -- 125,034,340(+) CTTGC(A/C)AAGAA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4296 Gene

Variant ID Type Subtype PubMed ID
esv3624823 CNV loss 21293372

Relevant External Links for MIR4296 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4296

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4296 Gene

Disorders for MIR4296 Gene

Relevant External Links for MIR4296

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4296

No disorders were found for MIR4296 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4296 Gene

Publications for MIR4296 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4296 Gene

Sources for MIR4296 Gene

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