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Aliases for MIR4291 Gene

Subcategory (RNA class) for MIR4291 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4291 Gene

  • MicroRNA 4291 2 3 5
  • Hsa-Mir-4291 3

External Ids for MIR4291 Gene

Previous GeneCards Identifiers for MIR4291 Gene

  • GC09U901625
  • GC09P096581

Summaries for MIR4291 Gene

Entrez Gene Summary for MIR4291 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4291 Gene

MIR4291 (MicroRNA 4291) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4291 Gene

Genomics for MIR4291 Gene

Regulatory Elements for MIR4291 Gene

Enhancers for MIR4291 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09G093826 1 Ensembl ENCODE 0.4 +7.8 7797 1.9 BCOR CTCF PKNOX1 CBX3 RB1 ZMYM3 ZNF384 CEBPG RBBP5 RAD21 ENSG00000269946 FGD3 MIR4291 ENSG00000231990
GH09G093807 0.7 ENCODE 0.4 -11.0 -10980 1.4 LEF1 RFX1 TAL1 NCOA1 MNT DPF2 ZKSCAN1 ZNF592 TCF12 ARID1B LOC101928014 MIR4291
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4291 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4291 Gene

Chromosome:
9
Start:
93,819,357 bp from pter
End:
93,819,421 bp from pter
Size:
65 bases
Orientation:
Plus strand

Genomic View for MIR4291 Gene

Genes around MIR4291 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4291 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4291 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4291 Gene

Proteins for MIR4291 Gene

Post-translational modifications for MIR4291 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4291 Gene

Domains & Families for MIR4291 Gene

Gene Families for MIR4291 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4291: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4291 Gene

Function for MIR4291 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4291 Gene

Localization for MIR4291 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4291 Gene

Pathways & Interactions for MIR4291 Gene

SuperPathways for MIR4291 Gene

No Data Available

Interacting Proteins for MIR4291 Gene

Gene Ontology (GO) - Biological Process for MIR4291 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4291 Gene

Transcripts for MIR4291 Gene

mRNA/cDNA for MIR4291 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4291 Gene

No ASD Table

Relevant External Links for MIR4291 Gene

GeneLoc Exon Structure for
MIR4291
ECgene alternative splicing isoforms for
MIR4291

Expression for MIR4291 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4291 Gene:

MIR4291
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4291 Gene

Orthologs for MIR4291 Gene

Evolution for MIR4291 Gene

ENSEMBL:
Gene Tree for MIR4291 (if available)
TreeFam:
Gene Tree for MIR4291 (if available)

No data available for Orthologs for MIR4291 Gene

Paralogs for MIR4291 Gene

No data available for Paralogs for MIR4291 Gene

Variants for MIR4291 Gene

Sequence variations from dbSNP and Humsavar for MIR4291 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1001368647 -- 93,817,641(+) AAATG(A/G)CACTT upstream-variant-2KB
rs1003070119 -- 93,819,539(+) TCCAC(A/C)GAAAC downstream-variant-500B
rs1003196289 -- 93,818,768(+) GAACA(C/T)GACTA upstream-variant-2KB
rs1003502635 -- 93,819,028(+) GACAG(A/G)ACCCC upstream-variant-2KB
rs1004708193 -- 93,818,791(+) GGTAT(A/G)TCTCT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4291 Gene

Variant ID Type Subtype PubMed ID
nsv6619 CNV insertion 18451855

Relevant External Links for MIR4291 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4291

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4291 Gene

Disorders for MIR4291 Gene

Relevant External Links for MIR4291

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4291

No disorders were found for MIR4291 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4291 Gene

Publications for MIR4291 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4291 Gene

Sources for MIR4291 Gene

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