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Aliases for MIR4290 Gene

Subcategory (RNA class) for MIR4290 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4290 Gene

  • MicroRNA 4290 2 3 5
  • Hsa-Mir-4290 3

External Ids for MIR4290 Gene

Previous GeneCards Identifiers for MIR4290 Gene

  • GC09U901557
  • GC09M092785

Summaries for MIR4290 Gene

Entrez Gene Summary for MIR4290 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4290 Gene

MIR4290 (MicroRNA 4290) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4290 Gene

Genomics for MIR4290 Gene

Regulatory Elements for MIR4290 Gene

Enhancers for MIR4290 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09G089998 2 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +22.1 22117 5.3 HNRNPUL1 HDGF FOXA2 PKNOX1 ARNT MLX CREB3L1 ARID4B SIN3A DMAP1 GC09M089956 MIR4290
GH09G090019 0.8 ENCODE dbSUPER 0.7 +3.4 3355 1.9 GATA3 RFX1 CTBP1 ESRRA MNT FOS CUX1 MIR4290 GC09M089956
GH09G090006 1.3 Ensembl ENCODE dbSUPER 0.4 +15.8 15766 2.0 HDAC1 CTCF ESRRA TFAP4 CBX3 TBL1XR1 SAP130 DMAP1 ZNF766 FOXK2 MIR4290 GC09M089956
GH09G089992 1.7 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +29.5 29459 4.1 FOXA2 MLX ZFP64 ARID4B YBX1 GLI4 ZNF48 YY1 SP5 PPARG GADD45G GC09M089956 MIR4290
GH09G089983 1.2 Ensembl ENCODE dbSUPER 0.3 +39.2 39231 1.1 CBFB NR2F1 JUNB EP300 NR2F2 ETV4 SCRT2 NR2C1 NR2F6 FOS GC09M089956 MIR4290
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4290 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4290 Gene

Chromosome:
9
Start:
90,023,441 bp from pter
End:
90,023,535 bp from pter
Size:
95 bases
Orientation:
Minus strand

Genomic View for MIR4290 Gene

Genes around MIR4290 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4290 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4290 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4290 Gene

Proteins for MIR4290 Gene

Post-translational modifications for MIR4290 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4290 Gene

Domains & Families for MIR4290 Gene

Gene Families for MIR4290 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4290: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4290 Gene

Function for MIR4290 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4290 Gene

Localization for MIR4290 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4290 Gene

Pathways & Interactions for MIR4290 Gene

SuperPathways for MIR4290 Gene

No Data Available

Interacting Proteins for MIR4290 Gene

Gene Ontology (GO) - Biological Process for MIR4290 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4290 Gene

Transcripts for MIR4290 Gene

mRNA/cDNA for MIR4290 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4290 Gene

No ASD Table

Relevant External Links for MIR4290 Gene

GeneLoc Exon Structure for
MIR4290
ECgene alternative splicing isoforms for
MIR4290

Expression for MIR4290 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4290 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4290 Gene:

MIR4290
genes like me logo Genes that share expression patterns with MIR4290: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4290 Gene

Orthologs for MIR4290 Gene

Evolution for MIR4290 Gene

ENSEMBL:
Gene Tree for MIR4290 (if available)
TreeFam:
Gene Tree for MIR4290 (if available)

No data available for Orthologs for MIR4290 Gene

Paralogs for MIR4290 Gene

No data available for Paralogs for MIR4290 Gene

Variants for MIR4290 Gene

Sequence variations from dbSNP and Humsavar for MIR4290 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1000246936 -- 90,024,979(+) TGGCC(-/CA)GAGCA nc-transcript-variant, upstream-variant-2KB
rs1000833976 -- 90,023,898(+) AGTCT(A/G)CATTG intron-variant, upstream-variant-2KB
rs1000884594 -- 90,025,530(+) ACCCT(G/T)CTGGC nc-transcript-variant, upstream-variant-2KB
rs1001371468 -- 90,024,107(+) CAACA(A/G)GCAGC intron-variant, upstream-variant-2KB
rs1001742089 -- 90,024,422(+) TAGAA(A/G)TTTTC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4290 Gene

Variant ID Type Subtype PubMed ID
esv3621038 CNV gain 21293372

Relevant External Links for MIR4290 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4290

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4290 Gene

Disorders for MIR4290 Gene

Relevant External Links for MIR4290

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4290

No disorders were found for MIR4290 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4290 Gene

Publications for MIR4290 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4290 Gene

Sources for MIR4290 Gene

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