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Aliases for MIR429 Gene

Subcategory (RNA class) for MIR429 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR429 Gene

  • MicroRNA 429 2 3
  • MIRN429 3 6
  • Hsa-Mir-429 3

External Ids for MIR429 Gene

ORGUL Members for MIR429 Gene

Previous Symbols for MIR429 Gene

  • MIRN429

Summaries for MIR429 Gene

Entrez Gene Summary for MIR429 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR429 Gene

MIR429 (MicroRNA 429) is a RNA Gene, and belongs to miRNA RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR429 Gene

Genomics for MIR429 Gene

Genomic Location for MIR429 Gene

Start:
1,169,005 bp from pter
End:
1,169,087 bp from pter
Size:
83 bases
Orientation:
Plus strand

Genomic View for MIR429 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR429 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR429 Gene

No data available for Regulatory Elements for MIR429 Gene

Proteins for MIR429 Gene

Post-translational modifications for MIR429 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR429 Gene

Domains for MIR429 Gene

Gene Families for MIR429 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR429: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR429 Gene

Function for MIR429 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR429 Gene

Localization for MIR429 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR429 Gene

Pathways for MIR429 Gene

SuperPathways for MIR429 Gene

No Data Available

Interacting Proteins for MIR429 Gene

Gene Ontology (GO) - Biological Process for MIR429 Gene

None

No data available for Pathways by source for MIR429 Gene

Transcripts for MIR429 Gene

mRNA/cDNA for MIR429 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR429 Gene

No ASD Table

Relevant External Links for MIR429 Gene

GeneLoc Exon Structure for
MIR429
ECgene alternative splicing isoforms for
MIR429

Expression for MIR429 Gene

mRNA expression in normal human tissues for MIR429 Gene

mRNA differential expression in normal tissues according to GTEx for MIR429 Gene

This gene is overexpressed in Colon - Transverse (9.9), Pituitary (6.6), Stomach (5.1), Pancreas (4.3), and Small Intestine - Terminal Ileum (4.2).
genes like me logo Genes that share expressions with MIR429: view

Orthologs for MIR429 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR429 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-429 37
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-429 37
  • 79 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir429 37
  • 83 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-429 37
  • 74 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-429 37
  • 54 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-429 37
  • 69 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-429 37
  • 55 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-429a 37
  • 72 (a)
OneToMany
dre-mir-429b 37
  • 50 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea csa-mir-141 37
  • 55 (a)
OneToMany
Species with no ortholog for MIR429:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR429 Gene

ENSEMBL:
Gene Tree for MIR429 (if available)
TreeFam:
Gene Tree for MIR429 (if available)

Paralogs for MIR429 Gene

No data available for Paralogs for MIR429 Gene

Variants for MIR429 Gene

Sequence variations from dbSNP and Humsavar for MIR429 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs7521584 -- 1,168,578(+) GGAAC(A/G/T)TTGTC upstream-variant-2KB
rs61050058 -- 1,169,405(+) GGCTG(A/G)GACAG downstream-variant-500B
rs74045167 -- 1,169,229(+) GGGCT(C/T)TTGTG downstream-variant-500B
rs112695918 -- 1,169,204(+) ATCAG(C/T)GCAAA downstream-variant-500B
rs112882180 -- 1,168,518(+) CTCTG(C/T)GCTTG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR429 Gene

Variant ID Type Subtype PubMed ID
nsv10161 CNV Gain+Loss 18304495
nsv517709 CNV Gain+Loss 19592680
nsv428334 CNV Gain 18775914
dgv2n67 CNV Gain 20364138
nsv871547 CNV Loss 21882294
dgv10n71 CNV Loss 21882294
dgv11n71 CNV Loss 21882294
dgv12n71 CNV Loss 21882294
dgv13n71 CNV Loss 21882294
nsv470680 CNV Loss 18288195
dgv17n71 CNV Loss 21882294
dgv18n71 CNV Loss 21882294
nsv871553 CNV Loss 21882294
dgv19n71 CNV Loss 21882294
dgv20n71 CNV Loss 21882294
nsv870527 CNV Gain 21882294
nsv469848 CNV Gain 16826518
nsv509257 CNV Insertion 20534489
dgv21n71 CNV Loss 21882294
nsv871744 CNV Gain 21882294
nsv482937 CNV Loss 15286789
nsv871079 CNV Loss 21882294
dgv22n71 CNV Loss 21882294

Relevant External Links for MIR429 Gene

HapMap Linkage Disequilibrium report
MIR429

Disorders for MIR429 Gene

No disorders were found for MIR429 Gene.

No data available for UniProtKB/Swiss-Prot for MIR429 Gene

Publications for MIR429 Gene

  1. Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. (PMID: 15735639) Xie X. … Kellis M. (Nature 2005) 3
  2. Clustering and conservation patterns of human microRNAs. (PMID: 15891114) Altuvia Y. … Margalit H. (Nucleic Acids Res. 2005) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  5. Patterns of known and novel small RNAs in human cervical cancer. (PMID: 17616659) Lui W.O. … Fire A. (Cancer Res. 2007) 3

Products for MIR429 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MIR429
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MIR429
    • Block miRNA regulation of MIR429 using miScript Target Protectors

    Sources for MIR429 Gene

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