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Aliases for MIR429 Gene

Subcategory (RNA class) for MIR429 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR429 Gene

  • MicroRNA 429 2 3 5
  • Hsa-Mir-429 3
  • Mir-429 3
  • MIRN429 3

External Ids for MIR429 Gene

ORGUL Members for MIR429 Gene

Previous HGNC Symbols for MIR429 Gene

  • MIRN429

Previous GeneCards Identifiers for MIR429 Gene

  • GC01P001102
  • GC01P001105
  • GC01P001109
  • GC01P001116
  • GC01P001130
  • GC01P001171
  • GC01P001175
  • GC01P001177
  • GC01P001180
  • GC01P001183

Summaries for MIR429 Gene

Entrez Gene Summary for MIR429 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR429 Gene

MIR429 (MicroRNA 429) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are miRNA targets in ECM and membrane receptors.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR429 Gene

Genomics for MIR429 Gene

Regulatory Elements for MIR429 Gene

Enhancers for MIR429 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G001189 1 FANTOM5 13.6 +20.4 20387 0.3 FOXA2 MLX ZFP64 ARID4B DMAP1 THRB RAD21 YY1 RARA GATA4 SDF4 B3GALT6 MIR200A MIR200B MIR429 UBE2J2 LINC01786 C1QTNF12 TNFRSF18 HES4
GH01G001109 0.9 ENCODE 11.6 -59.1 -59147 1.1 PKNOX1 ATF1 YY1 GATA2 NCOA1 REST ZNF592 CREB3 SMARCA4 NBN LINC01786 UBE2J2 MIR200A MIR200B MIR429 PERM1 PLEKHN1 C1orf159 GC01P001111 GC01M001107
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR429 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR429 Gene

Chromosome:
1
Start:
1,169,005 bp from pter
End:
1,169,087 bp from pter
Size:
83 bases
Orientation:
Plus strand

Genomic View for MIR429 Gene

Genes around MIR429 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR429 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR429 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR429 Gene

Proteins for MIR429 Gene

Post-translational modifications for MIR429 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR429 Gene

Domains & Families for MIR429 Gene

Gene Families for MIR429 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR429: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR429 Gene

Function for MIR429 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR429 Gene

Localization for MIR429 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR429 Gene

Pathways & Interactions for MIR429 Gene

genes like me logo Genes that share pathways with MIR429: view

Pathways by source for MIR429 Gene

1 BioSystems pathway for MIR429 Gene

Interacting Proteins for MIR429 Gene

Gene Ontology (GO) - Biological Process for MIR429 Gene

None

No data available for SIGNOR curated interactions for MIR429 Gene

Drugs & Compounds for MIR429 Gene

No Compound Related Data Available

Transcripts for MIR429 Gene

mRNA/cDNA for MIR429 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR429 Gene

No ASD Table

Relevant External Links for MIR429 Gene

GeneLoc Exon Structure for
MIR429
ECgene alternative splicing isoforms for
MIR429

Expression for MIR429 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR429 Gene

mRNA differential expression in normal tissues according to GTEx for MIR429 Gene

This gene is overexpressed in Colon - Transverse (x9.9), Pituitary (x6.6), Stomach (x5.1), Pancreas (x4.3), and Small Intestine - Terminal Ileum (x4.2).

NURSA nuclear receptor signaling pathways regulating expression of MIR429 Gene:

MIR429
genes like me logo Genes that share expression patterns with MIR429: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR429 Gene

Orthologs for MIR429 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR429 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-429 35
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir429 35
  • 83 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-429 35
  • 79 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-429 35
  • 74 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-429 35
  • 54 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-429 35
  • 69 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-429 35
  • 55 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-429a 35
  • 72 (a)
OneToMany
dre-mir-429b 35
  • 50 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea csa-mir-141 35
  • 55 (a)
OneToMany
Species where no ortholog for MIR429 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR429 Gene

ENSEMBL:
Gene Tree for MIR429 (if available)
TreeFam:
Gene Tree for MIR429 (if available)

Paralogs for MIR429 Gene

No data available for Paralogs for MIR429 Gene

Variants for MIR429 Gene

Sequence variations from dbSNP and Humsavar for MIR429 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1001809323 -- 1,167,265(+) CCACA(C/T)AGCCC downstream-variant-500B, upstream-variant-2KB
rs1002688307 -- 1,168,905(+) GGAGG(G/T)ATCAG upstream-variant-2KB
rs1003284241 -- 1,167,958(+) CGCTC(A/G)CCGGG downstream-variant-500B, upstream-variant-2KB
rs1003746029 -- 1,168,109(+) CAGAC(A/G)GGTGA downstream-variant-500B, upstream-variant-2KB
rs1003848660 -- 1,168,130(+) CTGAG(C/T)GGGCG downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR429 Gene

Variant ID Type Subtype PubMed ID
dgv2n67 CNV gain 20364138
nsv1003578 CNV gain 25217958
nsv10161 CNV gain+loss 18304495
nsv1160644 CNV deletion 26073780
nsv1160772 CNV duplication 26073780
nsv428334 CNV gain 18775914
nsv469848 CNV gain 16826518
nsv470680 CNV loss 18288195
nsv482937 CNV loss 15286789
nsv509257 CNV insertion 20534489
nsv517709 CNV gain+loss 19592680
nsv544947 CNV loss 21841781
nsv544954 CNV loss 21841781
nsv950452 CNV deletion 24416366

Relevant External Links for MIR429 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR429

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR429 Gene

Disorders for MIR429 Gene

Relevant External Links for MIR429

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR429

No disorders were found for MIR429 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR429 Gene

Publications for MIR429 Gene

  1. Tumor suppressive microRNAa89429 regulates cellular function by targeting VEGF in clear cell renal cell carcinoma. (PMID: 26647818) Chen D. … Lai Y. (Mol Med Rep 2016) 3 64
  2. Downregulation of microRNA-429 protects cardiomyocytes against hypoxia-induced apoptosis by increasing Notch1 expression. (PMID: 27082497) Xu H. … Li J. (Int. J. Mol. Med. 2016) 3 64
  3. miR-429 regulates the transition between Hypoxia-Inducible Factor (HIF)1A and HIF3A expression in human endothelial cells. (PMID: 26954587) Janaszak-Jasiecka A. … Collawn J.F. (Sci Rep 2016) 3 64
  4. Downregulation of miRa89429 and inhibition of cell migration and invasion in nasopharyngeal carcinoma. (PMID: 26936585) Wang F. … Hu F. (Mol Med Rep 2016) 3 64
  5. The effects of Micro-429 on inhibition of cervical cancer cells through targeting ZEB1 and CRKL. (PMID: 27133071) Wang Y. … Wang W.L. (Biomed. Pharmacother. 2016) 3 64

Products for MIR429 Gene

Sources for MIR429 Gene

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