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Aliases for MIR4289 Gene

Subcategory (RNA class) for MIR4289 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4289 Gene

  • MicroRNA 4289 2 3
  • Hsa-Mir-4289 3

External Ids for MIR4289 Gene

Previous GeneCards Identifiers for MIR4289 Gene

  • GC09U901494
  • GC09M091360

Summaries for MIR4289 Gene

Entrez Gene Summary for MIR4289 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4289 Gene

MIR4289 (MicroRNA 4289) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4289 Gene

Genomics for MIR4289 Gene

Genomic Location for MIR4289 Gene

Start:
88,745,836 bp from pter
End:
88,745,905 bp from pter
Size:
70 bases
Orientation:
Minus strand

Genomic View for MIR4289 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR4289 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4289 Gene

ORGUL Member Location for MIR4289 Gene

ORGUL Member Location for MIR4289 gene

No data available for Regulatory Elements for MIR4289 Gene

Proteins for MIR4289 Gene

Post-translational modifications for MIR4289 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4289 Gene

Domains for MIR4289 Gene

Gene Families for MIR4289 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4289: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4289 Gene

Function for MIR4289 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR4289 Gene

Localization for MIR4289 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4289 Gene

Pathways for MIR4289 Gene

SuperPathways for MIR4289 Gene

No Data Available

Interacting Proteins for MIR4289 Gene

Gene Ontology (GO) - Biological Process for MIR4289 Gene

None

No data available for Pathways by source for MIR4289 Gene

Transcripts for MIR4289 Gene

mRNA/cDNA for MIR4289 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4289 Gene

No ASD Table

Relevant External Links for MIR4289 Gene

GeneLoc Exon Structure for
MIR4289
ECgene alternative splicing isoforms for
MIR4289

Expression for MIR4289 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR4289 Gene

Orthologs for MIR4289 Gene

Evolution for MIR4289 Gene

ENSEMBL:
Gene Tree for MIR4289 (if available)
TreeFam:
Gene Tree for MIR4289 (if available)

No data available for Orthologs for MIR4289 Gene

Paralogs for MIR4289 Gene

No data available for Paralogs for MIR4289 Gene

Variants for MIR4289 Gene

Sequence variations from dbSNP and Humsavar for MIR4289 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs4877074 -- 88,746,409(+) TAGGC(A/G)CAGGG upstream-variant-2KB
rs7855763 -- 88,747,260(+) TGCTT(A/G)TGGCC upstream-variant-2KB
rs7856505 -- 88,747,876(+) AAAAG(A/C)AATTA upstream-variant-2KB
rs7858222 -- 88,746,952(+) GCTGT(C/T)AGACT upstream-variant-2KB
rs7866286 -- 88,747,703(+) CAGTC(A/G)GTCCA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4289 Gene

Variant ID Type Subtype PubMed ID
nsv831650 CNV Gain 17160897

Relevant External Links for MIR4289 Gene

HapMap Linkage Disequilibrium report
MIR4289

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR4289 Gene

Disorders for MIR4289 Gene

No disorders were found for MIR4289 Gene.

No data available for UniProtKB/Swiss-Prot for MIR4289 Gene

Publications for MIR4289 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3

Products for MIR4289 Gene

Sources for MIR4289 Gene

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