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Aliases for MIR4287 Gene

Subcategory (RNA class) for MIR4287 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4287 Gene

  • MicroRNA 4287 2 3 5
  • Hsa-Mir-4287 3

External Ids for MIR4287 Gene

Previous GeneCards Identifiers for MIR4287 Gene

  • GC08U901381
  • GC08M027743

Summaries for MIR4287 Gene

Entrez Gene Summary for MIR4287 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4287 Gene

MIR4287 (MicroRNA 4287) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4287 Gene

Genomics for MIR4287 Gene

Regulatory Elements for MIR4287 Gene

Enhancers for MIR4287 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08F027893 1.7 VISTA Ensembl ENCODE 0.4 -8.4 -8403 3.0 ATF1 MLX ARID4B RAD21 YY1 RARA GATA4 RCOR1 CREM HMG20B ENSG00000253290 LOC105379342 MIR4287
GH08F027871 1.6 FANTOM5 Ensembl ENCODE 0.4 +13.3 13292 2.4 ATF1 FEZF1 BRCA1 ZNF2 GTF3C2 ZNF121 KLF7 FOS DEK ZNF263 ZNF395 CCDC25 SCARA3 PBK ELP3 MIR4287 LOC100130612
GH08F027890 0.9 ENCODE 0.4 -5.6 -5592 1.5 TBP BRCA1 RFX5 RCOR1 FOS DEK SP5 CEBPB USF2 REST ENSG00000253290 MIR4287 LOC105379342
GH08F027897 0.8 Ensembl ENCODE 0.4 -11.7 -11672 1.4 ZNF316 EMSY MAFK NR2F2 ENSG00000253290 LOC105379342 MIR4287
GH08F027900 1 Ensembl ENCODE 0.3 -15.7 -15653 3.2 GTF2F1 CTCF KLF1 KLF17 MAX ZIC2 RAD21 ZKSCAN1 PATZ1 SMC3 ENSG00000253290 ENSG00000253397 CCDC25 LOC105379342 MIR4287
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4287 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4287 Gene

Chromosome:
8
Start:
27,886,039 bp from pter
End:
27,886,116 bp from pter
Size:
78 bases
Orientation:
Minus strand

Genomic View for MIR4287 Gene

Genes around MIR4287 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4287 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4287 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4287 Gene

Proteins for MIR4287 Gene

Post-translational modifications for MIR4287 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4287 Gene

Domains & Families for MIR4287 Gene

Gene Families for MIR4287 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4287: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4287 Gene

Function for MIR4287 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4287 Gene

Localization for MIR4287 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4287 Gene

Pathways & Interactions for MIR4287 Gene

SuperPathways for MIR4287 Gene

No Data Available

Interacting Proteins for MIR4287 Gene

Gene Ontology (GO) - Biological Process for MIR4287 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4287 Gene

Transcripts for MIR4287 Gene

mRNA/cDNA for MIR4287 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4287 Gene

No ASD Table

Relevant External Links for MIR4287 Gene

GeneLoc Exon Structure for
MIR4287
ECgene alternative splicing isoforms for
MIR4287

Expression for MIR4287 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4287 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4287 Gene:

MIR4287
genes like me logo Genes that share expression patterns with MIR4287: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4287 Gene

Orthologs for MIR4287 Gene

Evolution for MIR4287 Gene

ENSEMBL:
Gene Tree for MIR4287 (if available)
TreeFam:
Gene Tree for MIR4287 (if available)

No data available for Orthologs for MIR4287 Gene

Paralogs for MIR4287 Gene

No data available for Paralogs for MIR4287 Gene

Variants for MIR4287 Gene

Sequence variations from dbSNP and Humsavar for MIR4287 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs10090871 -- 27,886,847(+) TCAGA(A/C)GTGGT intron-variant, upstream-variant-2KB
rs10103460 -- 27,886,652(+) CCAAC(A/G)CCCTC intron-variant, upstream-variant-2KB
rs10104456 -- 27,886,747(+) TTTTC(C/T)CGGCA intron-variant, upstream-variant-2KB
rs115946976 -- 27,887,140(+) GCTTT(C/T)GAGGT intron-variant, upstream-variant-2KB
rs116120476 -- 27,886,193(+) GGCCT(A/G)TTCCT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4287 Gene

Variant ID Type Subtype PubMed ID
nsv509259 CNV insertion 20534489
nsv610868 CNV loss 21841781
nsv6133 CNV insertion 18451855

Relevant External Links for MIR4287 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4287

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4287 Gene

Disorders for MIR4287 Gene

Relevant External Links for MIR4287

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4287

No disorders were found for MIR4287 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4287 Gene

Publications for MIR4287 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4287 Gene

Sources for MIR4287 Gene

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