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Aliases for MIR4286 Gene

Subcategory (RNA class) for MIR4286 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4286 Gene

  • MicroRNA 4286 2 3 5
  • Hsa-Mir-4286 3
  • Mir-4286 3

External Ids for MIR4286 Gene

Previous GeneCards Identifiers for MIR4286 Gene

  • GC08U901409
  • GC08P009454
  • GC08P010524

Summaries for MIR4286 Gene

Entrez Gene Summary for MIR4286 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4286 Gene

MIR4286 (MicroRNA 4286) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4286 Gene

Genomics for MIR4286 Gene

Regulatory Elements for MIR4286 Gene

Enhancers for MIR4286 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08F010651 1.3 Ensembl ENCODE 0.4 -13.1 -13089 3.8 HDGF PKNOX1 FEZF1 ZNF2 GLIS2 FOS ZNF263 JUNB TSHZ1 ZNF488 RNA5SP252 LINC00529 ENSG00000249316 LINC00208 LOC105379241 PRSS52P LOC100420053 LOC101929290 RP1L1 PINX1
GH08F010627 1 Ensembl ENCODE 0.3 -36.6 -36558 5.0 IRF2 ESRRA SUZ12 JUN ZBTB40 STAT2 RFX1 STAT1 L3MBTL2 HLF LOC105379241 ENSG00000269954 ENSG00000269918 ENSG00000272505 PRSS51 XKR6 ENSG00000255310 MIR4286 LOC105379237
GH08F010636 0.8 Ensembl ENCODE 0.3 -30.3 -30290 1.4 RNF2 KLF16 NR2F1 ZMYM3 FOXP2 NR2F6 MYC ENSG00000269954 PRSS51 ENSG00000255310 MIR4286 LOC105379237
GH08F010598 0.9 Ensembl ENCODE 0.2 -68.5 -68478 1.0 CTCF STAT1 NFIA JUN ZIC2 ZFP69B JUND ZNF692 IKZF1 FOS LOC105379241 LOC105379237 MIR4286
GH08F010587 0.8 ENCODE 0.2 -79.5 -79473 0.2 CTCF PKNOX1 TAL1 ARID4B EBF1 ZNF2 RAD21 ZNF316 NCOR1 SMC3 SOX7 LOC101929229 PINX1 RP1L1 LOC102723313 LOC105379237 MIR4286
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4286 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4286 Gene

Chromosome:
8
Start:
10,666,978 bp from pter
End:
10,667,070 bp from pter
Size:
93 bases
Orientation:
Plus strand

Genomic View for MIR4286 Gene

Genes around MIR4286 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4286 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4286 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4286 Gene

Proteins for MIR4286 Gene

Post-translational modifications for MIR4286 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4286 Gene

Domains & Families for MIR4286 Gene

Gene Families for MIR4286 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4286: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4286 Gene

Function for MIR4286 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4286 Gene

Localization for MIR4286 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4286 Gene

Pathways & Interactions for MIR4286 Gene

SuperPathways for MIR4286 Gene

No Data Available

Interacting Proteins for MIR4286 Gene

Gene Ontology (GO) - Biological Process for MIR4286 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4286 Gene

Transcripts for MIR4286 Gene

mRNA/cDNA for MIR4286 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4286 Gene

No ASD Table

Relevant External Links for MIR4286 Gene

GeneLoc Exon Structure for
MIR4286
ECgene alternative splicing isoforms for
MIR4286

Expression for MIR4286 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4286 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4286 Gene:

MIR4286
genes like me logo Genes that share expression patterns with MIR4286: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4286 Gene

Orthologs for MIR4286 Gene

Evolution for MIR4286 Gene

ENSEMBL:
Gene Tree for MIR4286 (if available)
TreeFam:
Gene Tree for MIR4286 (if available)

No data available for Orthologs for MIR4286 Gene

Paralogs for MIR4286 Gene

No data available for Paralogs for MIR4286 Gene

Variants for MIR4286 Gene

Sequence variations from dbSNP and Humsavar for MIR4286 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs112683674 -- 10,667,339(+) TATAT(C/T)GGGAG downstream-variant-500B
rs113655180 -- 10,666,679(+) AAGAA(A/T)GAAAG upstream-variant-2KB
rs114547575 -- 10,665,865(+) ACACA(C/T)ACCAC upstream-variant-2KB
rs114747759 -- 10,665,777(+) ACCCA(A/C)GTGTC upstream-variant-2KB
rs115716855 -- 10,667,431(+) CCTCC(C/T)CCACA downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4286 Gene

Variant ID Type Subtype PubMed ID
nsv1025557 CNV gain 25217958
nsv1030934 CNV gain 25217958
nsv610267 CNV gain 21841781

Relevant External Links for MIR4286 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4286

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4286 Gene

Disorders for MIR4286 Gene

Relevant External Links for MIR4286

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4286

No disorders were found for MIR4286 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4286 Gene

Publications for MIR4286 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4286 Gene

Sources for MIR4286 Gene

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