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Aliases for MIR4285 Gene

Subcategory (RNA class) for MIR4285 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4285 Gene

  • MicroRNA 4285 2 3 5
  • Hsa-Mir-4285 3

External Ids for MIR4285 Gene

Previous GeneCards Identifiers for MIR4285 Gene

  • GC07U902929
  • GC07P096526
  • GC07P101937

Summaries for MIR4285 Gene

Entrez Gene Summary for MIR4285 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4285 Gene

MIR4285 (MicroRNA 4285) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4285 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4285 Gene

Genomics for MIR4285 Gene

GeneHancer (GH) Regulatory Elements for MIR4285 Gene

Promoters and enhancers for MIR4285 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I102291 Enhancer 0.7 ENCODE 550.8 -1.5 -1471 1.1 RB1 SIN3A EBF1 ZIC2 IRF4 RELA ZNF121 ZFHX2 EGR1 NFATC1 MIR4285 SH2B2 GC07P102225
GH07I102292 Enhancer 0.5 Ensembl 550.8 +0.1 133 1.3 ZNF148 ZFHX2 VEZF1 KLF9 ZMYM3 EGR2 MIR4285 SH2B2 ENSG00000170409 GC07P102225
GH07I102284 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE 0.4 -6.4 -6380 5.4 PKNOX1 ARID4B SIN3A ZNF2 ZBTB7B YY1 POLR2B ZNF143 SP3 SP5 SH2B2 CUX1 ORAI2 ENSG00000239486 POLR2J ARMC10 COL26A1 PRKRIP1 POLR2J3 ALKBH4
GH07I102294 Enhancer 0.7 Ensembl ENCODE 0.8 +2.5 2496 1.2 ZNF449 ZNF341 ZNF239 EBF1 NR2F6 EGR2 SH2B2 POLR2J2 MIR4285 ENSG00000170409 GC07P102225
GH07I102301 Enhancer 1.1 Ensembl ENCODE 0.4 +11.5 11536 7.2 HDGF PKNOX1 FOXA2 ARID4B SIN3A IRF4 GLIS2 ZNF207 ZNF143 ATF7 PRKRIP1 ENSG00000239486 ENSG00000213385 POLR2J2 SH2B2 ENSG00000272949 MIR4285 ENSG00000170409 GC07P102225
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4285 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4285 Gene

Genomic Locations for MIR4285 Gene
chr7:102,293,103-102,293,187
(GRCh38/hg38)
Size:
85 bases
Orientation:
Plus strand
chr7:101,936,369-101,936,453
(GRCh37/hg19)

Genomic View for MIR4285 Gene

Genes around MIR4285 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4285 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4285 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4285 Gene

Proteins for MIR4285 Gene

Post-translational modifications for MIR4285 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4285 Gene

Domains & Families for MIR4285 Gene

Gene Families for MIR4285 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4285: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4285 Gene

Function for MIR4285 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4285 Gene

Localization for MIR4285 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4285 Gene

Pathways & Interactions for MIR4285 Gene

SuperPathways for MIR4285 Gene

No Data Available

Interacting Proteins for MIR4285 Gene

Gene Ontology (GO) - Biological Process for MIR4285 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4285 Gene

Drugs & Compounds for MIR4285 Gene

No Compound Related Data Available

Transcripts for MIR4285 Gene

mRNA/cDNA for MIR4285 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4285 Gene

No ASD Table

Relevant External Links for MIR4285 Gene

GeneLoc Exon Structure for
MIR4285
ECgene alternative splicing isoforms for
MIR4285

Expression for MIR4285 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4285 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4285 Gene:

MIR4285
genes like me logo Genes that share expression patterns with MIR4285: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4285 Gene

Orthologs for MIR4285 Gene

Evolution for MIR4285 Gene

ENSEMBL:
Gene Tree for MIR4285 (if available)
TreeFam:
Gene Tree for MIR4285 (if available)

No data available for Orthologs for MIR4285 Gene

Paralogs for MIR4285 Gene

No data available for Paralogs for MIR4285 Gene

Variants for MIR4285 Gene

Sequence variations from dbSNP and Humsavar for MIR4285 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1003453606 -- 102,293,025(+) G/A upstream_transcript_variant
rs1006251068 -- 102,291,794(+) T/A upstream_transcript_variant
rs1007210103 -- 102,292,976(+) C/T upstream_transcript_variant
rs1007262542 -- 102,292,795(+) T/C upstream_transcript_variant
rs1010832274 -- 102,293,539(+) G/C/T downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4285 Gene

Variant ID Type Subtype PubMed ID
dgv11539n54 CNV loss 21841781
dgv6538n100 CNV gain 25217958
esv2759548 CNV gain 17122850
nsv428182 CNV gain 18775914
nsv509218 CNV insertion 20534489
nsv831082 CNV gain 17160897
nsv949918 CNV deletion 24416366

Additional Variant Information for MIR4285 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4285

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4285 Gene

Disorders for MIR4285 Gene

Additional Disease Information for MIR4285

No disorders were found for MIR4285 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4285 Gene

Publications for MIR4285 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4285 Gene

Sources for MIR4285 Gene

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