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Aliases for MIR4284 Gene

Subcategory (RNA class) for MIR4284 Gene


Quality Score for this RNA gene is


Aliases for MIR4284 Gene

  • MicroRNA 4284 2 3 5
  • Hsa-Mir-4284 3
  • Mir-4284 3

External Ids for MIR4284 Gene

Previous GeneCards Identifiers for MIR4284 Gene

  • GC07U903064
  • GC07P073125

Summaries for MIR4284 Gene

Entrez Gene Summary for MIR4284 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4284 Gene

MIR4284 (MicroRNA 4284) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR4284 include Pediatric Ulcerative Colitis.

Additional gene information for MIR4284 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4284 Gene

Genomics for MIR4284 Gene

Regulatory Elements for MIR4284 Gene

Enhancers for MIR4284 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07H073710 0.6 dbSUPER 0.7 +1.4 1406 3 BCOR SMARCA5 ZMYM3 ZIC2 ZNF121 HDAC2 KDM1A ZNF24 TBL2 VPS37D DNAJC30 NSUN5P2 MIR4284 STX1A
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4284 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4284 Gene

73,711,317 bp from pter
73,711,397 bp from pter
81 bases
Plus strand

Genomic View for MIR4284 Gene

Genes around MIR4284 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4284 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4284 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4284 Gene

Proteins for MIR4284 Gene

Post-translational modifications for MIR4284 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4284 Gene

Domains & Families for MIR4284 Gene

Gene Families for MIR4284 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4284: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4284 Gene

Function for MIR4284 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4284
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4284 Gene

Localization for MIR4284 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4284 Gene

Pathways & Interactions for MIR4284 Gene

SuperPathways for MIR4284 Gene

No Data Available

Interacting Proteins for MIR4284 Gene

Gene Ontology (GO) - Biological Process for MIR4284 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4284 Gene

Drugs & Compounds for MIR4284 Gene

No Compound Related Data Available

Transcripts for MIR4284 Gene

mRNA/cDNA for MIR4284 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4284
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4284 Gene

No ASD Table

Relevant External Links for MIR4284 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4284 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4284 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4284 Gene:

genes like me logo Genes that share expression patterns with MIR4284: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4284 Gene

Orthologs for MIR4284 Gene

Evolution for MIR4284 Gene

Gene Tree for MIR4284 (if available)
Gene Tree for MIR4284 (if available)

No data available for Orthologs for MIR4284 Gene

Paralogs for MIR4284 Gene

No data available for Paralogs for MIR4284 Gene

Variants for MIR4284 Gene

Sequence variations from dbSNP and Humsavar for MIR4284 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1002263780 -- 73,709,752(+) CCCAA(C/G)CTCCC intron-variant, upstream-variant-2KB
rs1004282856 -- 73,709,431(+) CAAGC(A/G)AGCCT intron-variant, upstream-variant-2KB
rs1004500765 -- 73,710,909(+) ATGGG(G/T)ACAGT intron-variant, upstream-variant-2KB
rs1004616881 -- 73,710,682(+) GGCCT(C/T)CCAAA intron-variant, upstream-variant-2KB
rs1004617508 -- 73,709,704(+) CAACC(A/G)TGCCT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4284 Gene

Variant ID Type Subtype PubMed ID
nsv469841 CNV loss 16826518
nsv831028 CNV loss 17160897

Relevant External Links for MIR4284 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4284 Gene

Disorders for MIR4284 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR4284 Gene - From: GeneCards

Disorder Aliases PubMed IDs
pediatric ulcerative colitis
  • ulcerative colitis, pediatric
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MIR4284

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR4284: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR4284 Gene

Publications for MIR4284 Gene

  1. Altered Plasma MicroRNAs as Novel Biomarkers for Arteriosclerosis Obliterans. (PMID: 26370316) He XM … Zhou XY (Journal of atherosclerosis and thrombosis 2016) 3 60
  2. A microRNA signature in pediatric ulcerative colitis: deregulation of the miR-4284/CXCL5 pathway in the intestinal epithelium. (PMID: 25738378) Koukos G … Iliopoulos D (Inflammatory bowel diseases 2015) 3 60
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  4. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 60
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4284 Gene

Sources for MIR4284 Gene

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