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Aliases for MIR4283-1 Gene

Subcategory (RNA class) for MIR4283-1 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4283-1 Gene

  • MicroRNA 4283-1 2 3
  • Hsa-Mir-4283-1 3

External Ids for MIR4283-1 Gene

Previous GeneCards Identifiers for MIR4283-1 Gene

  • GC07U903015
  • GC07M057024

Summaries for MIR4283-1 Gene

Entrez Gene Summary for MIR4283-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4283-1 Gene

MIR4283-1 (MicroRNA 4283-1) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4283-1 Gene

Genomics for MIR4283-1 Gene

Genomic Location for MIR4283-1 Gene

Start:
56,955,785 bp from pter
End:
56,955,864 bp from pter
Size:
80 bases
Orientation:
Minus strand

Genomic View for MIR4283-1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR4283-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4283-1 Gene

ORGUL Member Location for MIR4283-1 Gene

ORGUL Member Location for MIR4283-1 gene

No data available for Regulatory Elements for MIR4283-1 Gene

Proteins for MIR4283-1 Gene

Post-translational modifications for MIR4283-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4283-1 Gene

Domains for MIR4283-1 Gene

Gene Families for MIR4283-1 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4283-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4283-1 Gene

Function for MIR4283-1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR4283-1 Gene

Localization for MIR4283-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4283-1 Gene

Pathways for MIR4283-1 Gene

SuperPathways for MIR4283-1 Gene

No Data Available

Interacting Proteins for MIR4283-1 Gene

Gene Ontology (GO) - Biological Process for MIR4283-1 Gene

None

No data available for Pathways by source for MIR4283-1 Gene

Transcripts for MIR4283-1 Gene

mRNA/cDNA for MIR4283-1 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MIR4283-1
    • Block miRNA regulation of MIR4283-1 using miScript Target Protectors

    Inhibitory RNA Products

    • Predesigned siRNA for gene silencing in human,mouse,rat for MIR4283-1

    Primer Products

    Flow Cytometry Products

    Alternative Splicing Database (ASD) splice patterns (SP) for MIR4283-1 Gene

    No ASD Table

    Relevant External Links for MIR4283-1 Gene

    GeneLoc Exon Structure for
    MIR4283-1
    ECgene alternative splicing isoforms for
    MIR4283-1

    Expression for MIR4283-1 Gene

    No Expression Related Data Available

    In Situ Assay Products

    No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR4283-1 Gene

    Orthologs for MIR4283-1 Gene

    Evolution for MIR4283-1 Gene

    ENSEMBL:
    Gene Tree for MIR4283-1 (if available)
    TreeFam:
    Gene Tree for MIR4283-1 (if available)

    No data available for Orthologs for MIR4283-1 Gene

    Paralogs for MIR4283-1 Gene

    No data available for Paralogs for MIR4283-1 Gene

    Variants for MIR4283-1 Gene

    Sequence variations from dbSNP and Humsavar for MIR4283-1 Gene

    SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
    rs872064 -- 56,957,748(+) TTCCT(A/G)TGCTC upstream-variant-2KB
    rs872065 -- 56,957,772(+) TCCCC(A/G)TGGCA upstream-variant-2KB
    rs1717989 -- 56,955,515(+) GCTTT(C/G)AGGGG downstream-variant-500B
    rs2312117 -- 56,955,986(-) accac(A/G)cctgg upstream-variant-2KB
    rs57015505 -- 56,956,952(+) GGGAC(C/T)CGAGG upstream-variant-2KB

    Structural Variations from Database of Genomic Variants (DGV) for MIR4283-1 Gene

    Variant ID Type Subtype PubMed ID
    esv2734448 CNV Deletion 23290073
    esv2752160 CNV Gain 17911159
    esv2734468 CNV Deletion 23290073
    esv2675138 CNV Deletion 23128226
    nsv888068 CNV Gain 21882294
    dgv2086e1 CNV Complex 17122850
    esv2752164 CNV Gain 17911159
    nsv464513 CNV Gain 19166990
    essv17309 CNV CNV 17122850
    nsv888230 CNV Gain 21882294
    dgv7305n71 CNV Gain 21882294
    esv32550 CNV Gain+Loss 17666407
    nsv888253 CNV Gain 21882294
    nsv888254 CNV Gain 21882294

    Relevant External Links for MIR4283-1 Gene

    HapMap Linkage Disequilibrium report
    MIR4283-1

    No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR4283-1 Gene

    Disorders for MIR4283-1 Gene

    No disorders were found for MIR4283-1 Gene.

    No data available for UniProtKB/Swiss-Prot for MIR4283-1 Gene

    Publications for MIR4283-1 Gene

    1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
    2. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3

    Products for MIR4283-1 Gene

    Sources for MIR4283-1 Gene

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