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Aliases for MIR4283-1 Gene

Subcategory (RNA class) for MIR4283-1 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4283-1 Gene

  • MicroRNA 4283-1 2 3 5
  • Hsa-Mir-4283-1 3

External Ids for MIR4283-1 Gene

Previous GeneCards Identifiers for MIR4283-1 Gene

  • GC07U903015
  • GC07M057024

Summaries for MIR4283-1 Gene

Entrez Gene Summary for MIR4283-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4283-1 Gene

MIR4283-1 (MicroRNA 4283-1) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4283-1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4283-1 Gene

Genomics for MIR4283-1 Gene

Genomic Location for MIR4283-1 Gene

Chromosome:
7
Start:
56,955,785 bp from pter
End:
56,955,864 bp from pter
Size:
80 bases
Orientation:
Minus strand

Genomic View for MIR4283-1 Gene

Genes around MIR4283-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4283-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4283-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4283-1 Gene

ORGUL Member Location for MIR4283-1 Gene

ORGUL Member Location for MIR4283-1 gene

No data available for Regulatory Elements for MIR4283-1 Gene

Proteins for MIR4283-1 Gene

Post-translational modifications for MIR4283-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4283-1 Gene

Domains & Families for MIR4283-1 Gene

Gene Families for MIR4283-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4283-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4283-1 Gene

Function for MIR4283-1 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4283-1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4283-1 Gene

Localization for MIR4283-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4283-1 Gene

Pathways & Interactions for MIR4283-1 Gene

SuperPathways for MIR4283-1 Gene

No Data Available

Interacting Proteins for MIR4283-1 Gene

Gene Ontology (GO) - Biological Process for MIR4283-1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4283-1 Gene

Drugs & Compounds for MIR4283-1 Gene

No Compound Related Data Available

Transcripts for MIR4283-1 Gene

mRNA/cDNA for MIR4283-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4283-1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4283-1 Gene

No ASD Table

Relevant External Links for MIR4283-1 Gene

GeneLoc Exon Structure for
MIR4283-1
ECgene alternative splicing isoforms for
MIR4283-1

Expression for MIR4283-1 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4283-1 Gene

Orthologs for MIR4283-1 Gene

Evolution for MIR4283-1 Gene

ENSEMBL:
Gene Tree for MIR4283-1 (if available)
TreeFam:
Gene Tree for MIR4283-1 (if available)

No data available for Orthologs for MIR4283-1 Gene

Paralogs for MIR4283-1 Gene

No data available for Paralogs for MIR4283-1 Gene

Variants for MIR4283-1 Gene

Sequence variations from dbSNP and Humsavar for MIR4283-1 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs10266718 -- 56,956,954(-) GACCT(C/T)GGGTC upstream-variant-2KB
rs111261437 -- 56,955,872(+) CTGGG(C/T)CGTTC upstream-variant-2KB
rs111601908 -- 56,956,916(+) CTGCT(C/G)TGAAG upstream-variant-2KB
rs113840888 -- 56,956,193(+) GAGGC(A/G)GAGGT upstream-variant-2KB
rs113842021 -- 56,956,342(+) CCCCA(C/T)GATCC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4283-1 Gene

Variant ID Type Subtype PubMed ID
dgv6366n100 CNV loss 25217958
dgv6367n100 CNV gain 25217958
dgv6432n100 CNV gain 25217958
esv2675138 CNV deletion 23128226
esv2734448 CNV deletion 23290073
esv2734468 CNV deletion 23290073
esv2752160 CNV gain 17911159
esv2752164 CNV gain 17911159
esv2759533 CNV gain+loss 17122850
esv2761073 CNV loss 21179565
esv32550 CNV gain+loss 17666407
esv3571877 CNV loss 25503493
nsv1016541 CNV gain 25217958
nsv1016602 CNV loss 25217958
nsv1018445 CNV gain 25217958
nsv1023394 CNV gain 25217958
nsv1032341 CNV loss 25217958
nsv1033831 CNV gain 25217958
nsv464513 CNV gain 19166990
nsv607299 CNV gain 21841781
nsv970496 CNV duplication 23825009
nsv970844 CNV duplication 23825009

Relevant External Links for MIR4283-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4283-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4283-1 Gene

Disorders for MIR4283-1 Gene

Relevant External Links for MIR4283-1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4283-1

No disorders were found for MIR4283-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4283-1 Gene

Publications for MIR4283-1 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4283-1 Gene

Sources for MIR4283-1 Gene

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