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Aliases for MIR4282 Gene

Subcategory (RNA class) for MIR4282 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4282 Gene

  • MicroRNA 4282 2 3 5
  • Hsa-Mir-4282 3

External Ids for MIR4282 Gene

Previous GeneCards Identifiers for MIR4282 Gene

  • GC06U902015
  • GC06M073677

Summaries for MIR4282 Gene

Entrez Gene Summary for MIR4282 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4282 Gene

MIR4282 (MicroRNA 4282) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4282 Gene

Genomics for MIR4282 Gene

Regulatory Elements for MIR4282 Gene

Enhancers for MIR4282 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06F072968 0.6 ENCODE 0.8 -1.2 -1229 1.2 JUND ZNF366 SCRT2 JUN ZNF143 FOS EP300 KNOP1P4 MIR4282
GH06F072966 0.6 Ensembl 0.8 +1.1 1053 0.6 PRDM1 MIR4282 GC06M072905
GH06F072976 0.5 Ensembl 0.4 -9.3 -9348 1.0 PKNOX1 SPI1 EIF3EP1 KNOP1P4 MIR4282
GH06F072954 0.5 Ensembl ENCODE 0.4 +13.4 13353 0.8 ZNF263 ZNF316 ZBTB20 MIR4282 GC06M072905
GH06F072952 0.5 Ensembl ENCODE 0.4 +14.7 14657 1.7 JUN ZNF664 CTBP1 GATA3 ZNF316 IKZF1 NFE2 EMSY NFE2L2 ZBTB20 MIR4282 GC06M072905
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4282 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4282 Gene

Chromosome:
6
Start:
72,967,687 bp from pter
End:
72,967,753 bp from pter
Size:
67 bases
Orientation:
Minus strand

Genomic View for MIR4282 Gene

Genes around MIR4282 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4282 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4282 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4282 Gene

Proteins for MIR4282 Gene

Post-translational modifications for MIR4282 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4282 Gene

Domains & Families for MIR4282 Gene

Gene Families for MIR4282 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4282: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4282 Gene

Function for MIR4282 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4282 Gene

Localization for MIR4282 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4282 Gene

Pathways & Interactions for MIR4282 Gene

SuperPathways for MIR4282 Gene

No Data Available

Interacting Proteins for MIR4282 Gene

Gene Ontology (GO) - Biological Process for MIR4282 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4282 Gene

Transcripts for MIR4282 Gene

mRNA/cDNA for MIR4282 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4282 Gene

No ASD Table

Relevant External Links for MIR4282 Gene

GeneLoc Exon Structure for
MIR4282
ECgene alternative splicing isoforms for
MIR4282

Expression for MIR4282 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4282 Gene:

MIR4282
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4282 Gene

Orthologs for MIR4282 Gene

Evolution for MIR4282 Gene

ENSEMBL:
Gene Tree for MIR4282 (if available)
TreeFam:
Gene Tree for MIR4282 (if available)

No data available for Orthologs for MIR4282 Gene

Paralogs for MIR4282 Gene

No data available for Paralogs for MIR4282 Gene

Variants for MIR4282 Gene

Sequence variations from dbSNP and Humsavar for MIR4282 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs113116365 -- 72,967,783(+) GTCTC(A/G)GTAGG intron-variant, upstream-variant-2KB
rs114793984 -- 72,967,445(+) AAAGT(G/T)TGGGC intron-variant, downstream-variant-500B
rs115687617 -- 72,967,859(+) CCCAA(A/C/T)GTGTG intron-variant, upstream-variant-2KB
rs117510659 -- 72,967,892(+) GCACC(C/T)GACCC intron-variant, upstream-variant-2KB
rs118010484 -- 72,967,814(+) CAGGT(C/G)TCAAA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4282 Gene

Variant ID Type Subtype PubMed ID
nsv830691 CNV gain 17160897

Relevant External Links for MIR4282 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4282

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4282 Gene

Disorders for MIR4282 Gene

Relevant External Links for MIR4282

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4282

No disorders were found for MIR4282 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4282 Gene

Publications for MIR4282 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4282 Gene

Sources for MIR4282 Gene

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