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Aliases for MIR4282 Gene

Subcategory (RNA class) for MIR4282 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4282 Gene

  • MicroRNA 4282 2 3 5
  • Hsa-Mir-4282 3

External Ids for MIR4282 Gene

Previous GeneCards Identifiers for MIR4282 Gene

  • GC06U902015
  • GC06M073677

Summaries for MIR4282 Gene

Entrez Gene Summary for MIR4282 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4282 Gene

MIR4282 (MicroRNA 4282) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4282 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4282 Gene

Genomics for MIR4282 Gene

GeneHancer (GH) Regulatory Elements for MIR4282 Gene

Promoters and enhancers for MIR4282 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06I072968 Enhancer 0.5 ENCODE 550.8 -1.2 -1229 1.2 JUND ZNF366 JUN SCRT2 FOS EP300 FOXA1 MIR4282 KNOP1P4 LOC105377855 KCNQ5
GH06I072952 Enhancer 0.8 Ensembl ENCODE 0.4 +14.4 14406 2.2 JUN ZSCAN21 CTBP1 ZNF316 GATA3 IKZF1 BCL6B NFE2 ZBTB12 EMSY MIR4282 GC06M072905 LOC105377855 KCNQ5
GH06I072949 Enhancer 0.8 Ensembl ENCODE 0.4 +17.2 17222 1.5 JUN CEBPB CEBPG EP300 BRCA1 ATF4 MAFF JUND GATA3 FOS MIR4282 GC06M072905 LOC105377855 KCNQ5
GH06I072944 Enhancer 0.2 ENCODE 0.3 +23.1 23072 0.7 MIR4282 GC06M072905 KCNQ5
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4282 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4282 Gene

Genomic Locations for MIR4282 Gene
chr6:72,967,687-72,967,753
(GRCh38/hg38)
Size:
67 bases
Orientation:
Minus strand
chr6:73,677,410-73,677,476
(GRCh37/hg19)

Genomic View for MIR4282 Gene

Genes around MIR4282 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4282 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4282 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4282 Gene

Proteins for MIR4282 Gene

Post-translational modifications for MIR4282 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4282 Gene

Domains & Families for MIR4282 Gene

Gene Families for MIR4282 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4282: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4282 Gene

Function for MIR4282 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4282 Gene

Localization for MIR4282 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4282 Gene

Pathways & Interactions for MIR4282 Gene

SuperPathways for MIR4282 Gene

No Data Available

Interacting Proteins for MIR4282 Gene

Gene Ontology (GO) - Biological Process for MIR4282 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4282 Gene

Drugs & Compounds for MIR4282 Gene

No Compound Related Data Available

Transcripts for MIR4282 Gene

mRNA/cDNA for MIR4282 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4282 Gene

No ASD Table

Relevant External Links for MIR4282 Gene

GeneLoc Exon Structure for
MIR4282
ECgene alternative splicing isoforms for
MIR4282

Expression for MIR4282 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4282 Gene:

MIR4282
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4282 Gene

Orthologs for MIR4282 Gene

Evolution for MIR4282 Gene

ENSEMBL:
Gene Tree for MIR4282 (if available)
TreeFam:
Gene Tree for MIR4282 (if available)

No data available for Orthologs for MIR4282 Gene

Paralogs for MIR4282 Gene

No data available for Paralogs for MIR4282 Gene

Variants for MIR4282 Gene

Sequence variations from dbSNP and Humsavar for MIR4282 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000266486 -- 72,967,805(-) T/C upstream_transcript_variant
rs1003765163 -- 72,968,548(-) A/G upstream_transcript_variant
rs1005004636 -- 72,969,431(-) T/C upstream_transcript_variant
rs1005714216 -- 72,969,054(-) T/C upstream_transcript_variant
rs1005772893 -- 72,969,387(-) A/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4282 Gene

Variant ID Type Subtype PubMed ID
nsv830691 CNV gain 17160897

Additional Variant Information for MIR4282 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4282

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4282 Gene

Disorders for MIR4282 Gene

Additional Disease Information for MIR4282

No disorders were found for MIR4282 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4282 Gene

Publications for MIR4282 Gene

  1. MiR-4282 suppresses proliferation and mobility of human colorectal carcinoma cells by targeting semaphorin 3E. (PMID: 27120047) Kang X … Guan W (Panminerva medica 2016) 3 58
  2. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4282 Gene

Sources for MIR4282 Gene

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