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Aliases for MIR4278 Gene

Subcategory (RNA class) for MIR4278 Gene

miRNA

Quality Score for this RNA gene is

7

Aliases for MIR4278 Gene

  • MicroRNA 4278 2 3
  • Hsa-Mir-4278 3

External Ids for MIR4278 Gene

Previous GeneCards Identifiers for MIR4278 Gene

  • GC05U901383

Summaries for MIR4278 Gene

Entrez Gene Summary for MIR4278 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4278 Gene

MIR4278 (MicroRNA 4278) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4278 Gene

Genomics for MIR4278 Gene

Genomic Location for MIR4278 Gene

Start:
6,827,853 bp from pter
End:
6,827,921 bp from pter
Size:
69 bases
Orientation:
Minus strand

Genomic View for MIR4278 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR4278 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4278 Gene

ORGUL Member Location for MIR4278 Gene

ORGUL Member Location for MIR4278 gene

No data available for Regulatory Elements for MIR4278 Gene

Proteins for MIR4278 Gene

Post-translational modifications for MIR4278 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4278 Gene

Domains for MIR4278 Gene

Gene Families for MIR4278 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4278: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4278 Gene

Function for MIR4278 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR4278 Gene

Localization for MIR4278 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4278 Gene

Pathways for MIR4278 Gene

SuperPathways for MIR4278 Gene

No Data Available

Interacting Proteins for MIR4278 Gene

Gene Ontology (GO) - Biological Process for MIR4278 Gene

None

No data available for Pathways by source for MIR4278 Gene

Transcripts for MIR4278 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4278 Gene

No ASD Table

Relevant External Links for MIR4278 Gene

GeneLoc Exon Structure for
MIR4278
ECgene alternative splicing isoforms for
MIR4278

No data available for mRNA/cDNA for MIR4278 Gene

Expression for MIR4278 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR4278 Gene

Orthologs for MIR4278 Gene

No data available for Orthologs and Evolution for MIR4278 Gene

Paralogs for MIR4278 Gene

No data available for Paralogs for MIR4278 Gene

Variants for MIR4278 Gene

Sequence variations from dbSNP and Humsavar for MIR4278 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs275440 -- 6,828,116(-) TGGGG(C/T)TCTGA upstream-variant-2KB
rs275441 -- 6,827,741(-) TCCCT(A/G)CAAGA downstream-variant-500B
rs275442 -- 6,827,400(+) CGGCT(C/T)AAGTT downstream-variant-500B
rs275486 -- 6,829,269(-) CGGTA(A/G)AACAC upstream-variant-2KB
rs1456969 -- 6,827,434(-) AATTA(C/T)GACTT downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4278 Gene

Variant ID Type Subtype PubMed ID
nsv830196 CNV Gain 17160897
nsv880826 CNV Gain 21882294
nsv881283 CNV Loss 21882294
nsv4699 CNV Insertion 18451855

Relevant External Links for MIR4278 Gene

HapMap Linkage Disequilibrium report
MIR4278

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR4278 Gene

Disorders for MIR4278 Gene

No disorders were found for MIR4278 Gene.

No data available for UniProtKB/Swiss-Prot for MIR4278 Gene

Publications for MIR4278 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3

Products for MIR4278 Gene

Sources for MIR4278 Gene

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