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Aliases for MIR4277 Gene

Subcategory (RNA class) for MIR4277 Gene


Quality Score for this RNA gene is


Aliases for MIR4277 Gene

  • MicroRNA 4277 2 3 5
  • Hsa-Mir-4277 3

External Ids for MIR4277 Gene

Previous GeneCards Identifiers for MIR4277 Gene

  • GC05U901453

Summaries for MIR4277 Gene

Entrez Gene Summary for MIR4277 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4277 Gene

MIR4277 (MicroRNA 4277) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4277 Gene

Genomics for MIR4277 Gene

Regulatory Elements for MIR4277 Gene

Enhancers for MIR4277 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05F001709 0.5 Ensembl 0.8 -1.2 -1233 0.6 SDHAP3 MIR4277 GC05M001717
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4277 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4277 Gene

1,708,785 bp from pter
1,708,868 bp from pter
84 bases
Minus strand

Genomic View for MIR4277 Gene

Genes around MIR4277 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4277 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4277 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4277 Gene

ORGUL Member Location for MIR4277 Gene

ORGUL Member Location for MIR4277 gene

Proteins for MIR4277 Gene

Post-translational modifications for MIR4277 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4277 Gene

Domains & Families for MIR4277 Gene

Gene Families for MIR4277 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4277: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4277 Gene

Function for MIR4277 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4277 Gene

Localization for MIR4277 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4277 Gene

Pathways & Interactions for MIR4277 Gene

SuperPathways for MIR4277 Gene

No Data Available

Interacting Proteins for MIR4277 Gene

Gene Ontology (GO) - Biological Process for MIR4277 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4277 Gene

Transcripts for MIR4277 Gene

mRNA/cDNA for MIR4277 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4277 Gene

No ASD Table

Relevant External Links for MIR4277 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4277 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4277 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4277 Gene:

genes like me logo Genes that share expression patterns with MIR4277: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4277 Gene

Orthologs for MIR4277 Gene

Evolution for MIR4277 Gene

Gene Tree for MIR4277 (if available)
Gene Tree for MIR4277 (if available)

No data available for Orthologs for MIR4277 Gene

Paralogs for MIR4277 Gene

No data available for Paralogs for MIR4277 Gene

Variants for MIR4277 Gene

Sequence variations from dbSNP and Humsavar for MIR4277 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs10064945 -- 1,708,990(+) AGGAG(C/T)AGCAC intron-variant, upstream-variant-2KB
rs10079400 -- 1,708,989(+) CAGGA(A/G)CAGCA intron-variant, upstream-variant-2KB
rs111598353 -- 1,709,547(+) ACTCA(C/T)GAAAC intron-variant, upstream-variant-2KB
rs113386649 -- 1,709,780(+) TCAAC(A/G)TTGTC intron-variant, upstream-variant-2KB
rs113604871 -- 1,709,402(+) CGAGA(A/G)TCTGT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4277 Gene

Variant ID Type Subtype PubMed ID
esv3569910 CNV loss 25503493
esv3603817 CNV gain 21293372
esv3603818 CNV gain 21293372
esv8290 OTHER inversion 19470904

Relevant External Links for MIR4277 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4277 Gene

Disorders for MIR4277 Gene

Relevant External Links for MIR4277

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4277 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4277 Gene

Publications for MIR4277 Gene

  1. Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer. (PMID: 25086665) Wolpin B.M. … Amundadottir L.T. (Nat. Genet. 2014) 3 64
  2. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4277 Gene

Sources for MIR4277 Gene

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