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Aliases for MIR4276 Gene

Subcategory (RNA class) for MIR4276 Gene


Quality Score for this RNA gene is


Aliases for MIR4276 Gene

  • MicroRNA 4276 2 3 5
  • Hsa-Mir-4276 3

External Ids for MIR4276 Gene

Previous GeneCards Identifiers for MIR4276 Gene

  • GC04U901256
  • GC04P175344

Summaries for MIR4276 Gene

Entrez Gene Summary for MIR4276 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4276 Gene

MIR4276 (MicroRNA 4276) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4276 Gene

Genomics for MIR4276 Gene

Regulatory Elements for MIR4276 Gene

Enhancers for MIR4276 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04F174422 1.2 Ensembl ENCODE 0.8 -0.3 -321 1.5 HDAC1 ATF1 PKNOX1 CBX3 ARNT TBL1XR1 SIN3A CHAMP1 GATA2 FOS ENSG00000250596 LOC101928509 MIR4276 ENSG00000249875
GH04F174419 1.2 Ensembl ENCODE 0.8 -3.4 -3447 1.4 HDAC1 ATF1 PKNOX1 CBX3 CHAMP1 ELK1 GATA2 ETV6 CREM ZBTB2 ENSG00000250596 CEP44 MIR4276 ENSG00000249875
GH04F174427 0.4 Ensembl 0.8 +4.1 4106 0.6 MYNN CEBPB MIR4276 HPGD
GH04F174437 0.6 ENCODE 0.4 +13.9 13879 0.7 GATA2 CEBPB NFE2 EP300 NFE2L2 ENSG00000250596 MIR4276 HPGD
GH04F174400 0.8 Ensembl ENCODE 0.3 -21.8 -21801 2.5 JUND ZNF740 CEBPB ZEB2 NR3C1 EP300 TCF7L2 CEP44 MIR4276 ENSG00000249875
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4276 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4276 Gene

174,423,795 bp from pter
174,423,864 bp from pter
70 bases
Plus strand

Genomic View for MIR4276 Gene

Genes around MIR4276 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4276 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4276 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4276 Gene

Proteins for MIR4276 Gene

Post-translational modifications for MIR4276 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4276 Gene

Domains & Families for MIR4276 Gene

Gene Families for MIR4276 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4276: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4276 Gene

Function for MIR4276 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4276 Gene

Localization for MIR4276 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4276 Gene

Pathways & Interactions for MIR4276 Gene

SuperPathways for MIR4276 Gene

No Data Available

Interacting Proteins for MIR4276 Gene

Gene Ontology (GO) - Biological Process for MIR4276 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4276 Gene

Transcripts for MIR4276 Gene

mRNA/cDNA for MIR4276 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4276 Gene

No ASD Table

Relevant External Links for MIR4276 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4276 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4276 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4276 Gene

Orthologs for MIR4276 Gene

Evolution for MIR4276 Gene

Gene Tree for MIR4276 (if available)
Gene Tree for MIR4276 (if available)

No data available for Orthologs for MIR4276 Gene

Paralogs for MIR4276 Gene

No data available for Paralogs for MIR4276 Gene

Variants for MIR4276 Gene

Sequence variations from dbSNP and Humsavar for MIR4276 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs111484135 -- 174,423,454(+) TGTGT(-/GT)GTGTG upstream-variant-2KB
rs113421262 -- 174,423,325(+) TAAGA(G/T)AAACA upstream-variant-2KB
rs113771095 -- 174,424,274(+) GATCT(A/C)CTACA downstream-variant-500B
rs114775064 -- 174,424,308(+) ACAGT(A/G)TATTT downstream-variant-500B
rs115256714 -- 174,423,916(+) TTTCA(A/G)AACAG downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4276 Gene

Variant ID Type Subtype PubMed ID
nsv596234 CNV gain 21841781

Relevant External Links for MIR4276 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4276 Gene

Disorders for MIR4276 Gene

Relevant External Links for MIR4276

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4276 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4276 Gene

Publications for MIR4276 Gene

  1. Lung epithelial cells resist influenza A infection by inducing the expression of cytochrome c oxidase VIc which is modulated by miRNA 4276. (PMID: 25203353) Othumpangat S. … Beezhold D.H. (Virology 2014) 3 64
  2. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4276 Gene

Sources for MIR4276 Gene

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