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Aliases for MIR4274 Gene

Subcategory (RNA class) for MIR4274 Gene


Quality Score for this RNA gene is


Aliases for MIR4274 Gene

  • MicroRNA 4274 2 3 5
  • Hsa-Mir-4274 3

External Ids for MIR4274 Gene

Previous GeneCards Identifiers for MIR4274 Gene

  • GC04U901280

Summaries for MIR4274 Gene

Entrez Gene Summary for MIR4274 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4274 Gene

MIR4274 (MicroRNA 4274) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4274 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4274 Gene

Genomics for MIR4274 Gene

Regulatory Elements for MIR4274 Gene

Enhancers for MIR4274 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04H007460 0.6 ENCODE 0.7 +0.8 761 0 BHLHE40 USF2 MNT RARA RAD51 NR2C1 ATF7 RXRB NR2C2 PSAPL1 MIR4274 GC04M007519
GH04H007463 0.5 ENCODE 0.7 +3.5 3492 0 CTCF FOXA2 RAD21 PSAPL1 MIR4274 GC04M007519
GH04H007434 0.7 ENCODE 0.3 -24.4 -24380 1 SOX13 PKNOX1 SP5 CEBPB PPARG ZIC2 ZFP69B ZFHX2 GLIS2 ZNF692 PSAPL1 MIR4274
GH04H007508 0.3 FANTOM5 0.2 +48.3 48337 0 SORCS2 GC04M007519 MIR4274
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4274 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4274 Gene

7,460,028 bp from pter
7,460,118 bp from pter
91 bases
Plus strand

Genomic View for MIR4274 Gene

Genes around MIR4274 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4274 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4274 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4274 Gene

Proteins for MIR4274 Gene

Post-translational modifications for MIR4274 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4274 Gene

Domains & Families for MIR4274 Gene

Gene Families for MIR4274 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4274: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4274 Gene

Function for MIR4274 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4274
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4274 Gene

Localization for MIR4274 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4274 Gene

Pathways & Interactions for MIR4274 Gene

SuperPathways for MIR4274 Gene

No Data Available

Interacting Proteins for MIR4274 Gene

Gene Ontology (GO) - Biological Process for MIR4274 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4274 Gene

Drugs & Compounds for MIR4274 Gene

No Compound Related Data Available

Transcripts for MIR4274 Gene

mRNA/cDNA for MIR4274 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4274
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4274 Gene

No ASD Table

Relevant External Links for MIR4274 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4274 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4274 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4274 Gene:

genes like me logo Genes that share expression patterns with MIR4274: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4274 Gene

Orthologs for MIR4274 Gene

Evolution for MIR4274 Gene

Gene Tree for MIR4274 (if available)
Gene Tree for MIR4274 (if available)

No data available for Orthologs for MIR4274 Gene

Paralogs for MIR4274 Gene

No data available for Paralogs for MIR4274 Gene

Variants for MIR4274 Gene

Sequence variations from dbSNP and Humsavar for MIR4274 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs1001162934 -- 7,459,696(+) CTTCC(C/T)AGCAT intron-variant, upstream-variant-2KB
rs1001477951 -- 7,458,183(+) AGGCA(C/T)TGCTG intron-variant, upstream-variant-2KB
rs1002349769 -- 7,458,990(+) CCGGC(A/G)GGGGG intron-variant, upstream-variant-2KB
rs1002492562 -- 7,459,548(+) TGAAG(C/T)CCATG intron-variant, upstream-variant-2KB
rs1002830572 -- 7,460,453(+) GCCTG(A/G)AGTTG intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4274 Gene

Variant ID Type Subtype PubMed ID
esv34196 OTHER inversion 12058347
nsv469758 CNV loss 16826518
nsv508994 CNV insertion 20534489
nsv593569 CNV gain 21841781
nsv949781 CNV deletion 24416366

Relevant External Links for MIR4274 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4274 Gene

Disorders for MIR4274 Gene

Relevant External Links for MIR4274

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4274 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4274 Gene

Publications for MIR4274 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4274 Gene

Sources for MIR4274 Gene

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