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Aliases for MIR4273 Gene

Subcategory (RNA class) for MIR4273 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4273 Gene

  • MicroRNA 4273 2 3
  • Hsa-Mir-4273 3

External Ids for MIR4273 Gene

Previous GeneCards Identifiers for MIR4273 Gene

  • GC03U901568

Summaries for MIR4273 Gene

Entrez Gene Summary for MIR4273 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4273 Gene

MIR4273 (MicroRNA 4273) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4273 Gene

Genomics for MIR4273 Gene

Genomic Location for MIR4273 Gene

Start:
75,738,280 bp from pter
End:
75,738,363 bp from pter
Size:
84 bases
Orientation:
Plus strand

Genomic View for MIR4273 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR4273 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4273 Gene

No data available for Regulatory Elements for MIR4273 Gene

Proteins for MIR4273 Gene

Post-translational modifications for MIR4273 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4273 Gene

Domains for MIR4273 Gene

Gene Families for MIR4273 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4273: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4273 Gene

Function for MIR4273 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR4273 Gene

Localization for MIR4273 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MIR4273 Gene COMPARTMENTS Subcellular localization image for MIR4273 gene
Compartment Confidence
nucleus 3

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MIR4273 Gene

Pathways for MIR4273 Gene

SuperPathways for MIR4273 Gene

No Data Available

Interacting Proteins for MIR4273 Gene

Gene Ontology (GO) - Biological Process for MIR4273 Gene

None

No data available for Pathways by source for MIR4273 Gene

Transcripts for MIR4273 Gene

mRNA/cDNA for MIR4273 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4273 Gene

No ASD Table

Relevant External Links for MIR4273 Gene

GeneLoc Exon Structure for
MIR4273
ECgene alternative splicing isoforms for
MIR4273

Expression for MIR4273 Gene

mRNA expression in normal human tissues for MIR4273 Gene

genes like me logo Genes that share expressions with MIR4273: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR4273 Gene

Orthologs for MIR4273 Gene

Evolution for MIR4273 Gene

ENSEMBL:
Gene Tree for MIR4273 (if available)
TreeFam:
Gene Tree for MIR4273 (if available)

No data available for Orthologs for MIR4273 Gene

Paralogs for MIR4273 Gene

No data available for Paralogs for MIR4273 Gene

Variants for MIR4273 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4273 Gene

Variant ID Type Subtype PubMed ID
esv2422315 CNV Deletion 17116639
esv614 CNV CNV 17122850
nsv529016 CNV Gain 19592680
esv26581 CNV Gain+Loss 19812545
dgv1469e1 CNV Complex 17122850
nsv876983 CNV Gain 21882294
dgv1472e1 CNV Complex 17122850
dgv1473e1 CNV Complex 17122850
essv18298 CNV CNV 17122850
nsv428418 CNV Loss 18775914
nsv10283 CNV Gain+Loss 18304495
nsv876987 CNV Gain 21882294
dgv1474e1 CNV Complex 17122850
nsv821408 CNV Duplication 20802225
nsv822138 CNV Gain 20364138
nsv876988 CNV Loss 21882294
esv2436311 CNV Gain 19546169
dgv812n67 CNV Gain 20364138
nsv822140 CNV Loss 20364138
esv33470 CNV Loss 17666407
esv2725476 CNV Deletion 23290073
nsv471427 CNV Duplication 19718026
esv2725478 CNV Deletion 23290073
nsv513053 CNV Loss 21212237
esv2725479 CNV Deletion 23290073
esv9630 CNV Loss 19470904
esv2725481 CNV Deletion 23290073
esv2725482 CNV Deletion 23290073

Relevant External Links for MIR4273 Gene

HapMap Linkage Disequilibrium report
MIR4273

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR4273 Gene

Disorders for MIR4273 Gene

No disorders were found for MIR4273 Gene.

No data available for UniProtKB/Swiss-Prot for MIR4273 Gene

Publications for MIR4273 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3

Products for MIR4273 Gene

Sources for MIR4273 Gene

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