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Aliases for MIR4272 Gene

Subcategory (RNA class) for MIR4272 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4272 Gene

  • MicroRNA 4272 2 3 5
  • Hsa-Mir-4272 3

External Ids for MIR4272 Gene

Previous GeneCards Identifiers for MIR4272 Gene

  • GC03U901629

Summaries for MIR4272 Gene

Entrez Gene Summary for MIR4272 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4272 Gene

MIR4272 (MicroRNA 4272) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4272 Gene

Genomics for MIR4272 Gene

Regulatory Elements for MIR4272 Gene

Enhancers for MIR4272 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03G067297 0.9 ENCODE 0.2 +70.8 70807 0.3 FOXA2 MLX ARID4B DMAP1 ZNF48 MIER2 PPARG KAT8 SSRP1 MIER3 ENSG00000241884 MIR4272
GH03G067292 0.7 ENCODE 0.2 +67.5 67528 0.2 SOX13 GATAD2A FOXA2 NFIB FOXA3 CEBPB HMG20A CEBPG FOXA1 CTBP1 ENSG00000241884 MIR4272
GH03G067290 0.5 Ensembl 0.2 +65.0 65038 0.2 IKZF1 SPI1 FOXP1 SUCLG2 ENSG00000241884 MIR4272
GH03G067272 0.3 FANTOM5 0.2 +47.6 47611 0.2 ENSG00000241884 MIR4272
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4272 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4272 Gene

Chromosome:
3
Start:
67,225,464 bp from pter
End:
67,225,527 bp from pter
Size:
64 bases
Orientation:
Plus strand

Genomic View for MIR4272 Gene

Genes around MIR4272 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4272 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4272 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4272 Gene

Proteins for MIR4272 Gene

Post-translational modifications for MIR4272 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4272 Gene

Domains & Families for MIR4272 Gene

Gene Families for MIR4272 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4272: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4272 Gene

Function for MIR4272 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4272 Gene

Localization for MIR4272 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4272 Gene

Pathways & Interactions for MIR4272 Gene

SuperPathways for MIR4272 Gene

No Data Available

Interacting Proteins for MIR4272 Gene

Gene Ontology (GO) - Biological Process for MIR4272 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4272 Gene

Drugs & Compounds for MIR4272 Gene

No Compound Related Data Available

Transcripts for MIR4272 Gene

mRNA/cDNA for MIR4272 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4272 Gene

No ASD Table

Relevant External Links for MIR4272 Gene

GeneLoc Exon Structure for
MIR4272
ECgene alternative splicing isoforms for
MIR4272

Expression for MIR4272 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4272 Gene:

MIR4272
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4272 Gene

Orthologs for MIR4272 Gene

Evolution for MIR4272 Gene

ENSEMBL:
Gene Tree for MIR4272 (if available)
TreeFam:
Gene Tree for MIR4272 (if available)

No data available for Orthologs for MIR4272 Gene

Paralogs for MIR4272 Gene

No data available for Paralogs for MIR4272 Gene

Variants for MIR4272 Gene

Sequence variations from dbSNP and Humsavar for MIR4272 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1000951990 -- 67,223,731(+) AAAAT(A/G)TAATC upstream-variant-2KB
rs1003406562 -- 67,225,430(+) CATTA(A/G)CCAAC upstream-variant-2KB
rs1003521638 -- 67,225,119(+) GCAAA(A/G)TGAAT upstream-variant-2KB
rs1005913733 -- 67,224,453(+) CAGGG(A/G)GAACA upstream-variant-2KB
rs1005989685 -- 67,225,772(+) ATAAT(C/T)TCAGC downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4272 Gene

Variant ID Type Subtype PubMed ID
esv3596450 CNV gain 21293372
nsv1003158 CNV loss 25217958
nsv590546 CNV gain 21841781

Relevant External Links for MIR4272 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4272

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4272 Gene

Disorders for MIR4272 Gene

Relevant External Links for MIR4272

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4272

No disorders were found for MIR4272 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4272 Gene

Publications for MIR4272 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4272 Gene

Sources for MIR4272 Gene

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