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Aliases for MIR4268 Gene

Subcategory (RNA class) for MIR4268 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4268 Gene

  • MicroRNA 4268 2 3
  • Hsa-Mir-4268 3

External Ids for MIR4268 Gene

Previous GeneCards Identifiers for MIR4268 Gene

  • GC02U902138
  • GC02M220771

Summaries for MIR4268 Gene

Entrez Gene Summary for MIR4268 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4268 Gene

MIR4268 (MicroRNA 4268) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4268 Gene

Genomics for MIR4268 Gene

Genomic Location for MIR4268 Gene

Start:
219,906,502 bp from pter
End:
219,906,565 bp from pter
Size:
64 bases
Orientation:
Minus strand

Genomic View for MIR4268 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR4268 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4268 Gene

No data available for Regulatory Elements for MIR4268 Gene

Proteins for MIR4268 Gene

Post-translational modifications for MIR4268 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4268 Gene

Domains for MIR4268 Gene

Gene Families for MIR4268 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4268: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4268 Gene

Function for MIR4268 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR4268 Gene

Localization for MIR4268 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4268 Gene

Pathways for MIR4268 Gene

SuperPathways for MIR4268 Gene

No Data Available

Interacting Proteins for MIR4268 Gene

Gene Ontology (GO) - Biological Process for MIR4268 Gene

None

No data available for Pathways by source for MIR4268 Gene

Transcripts for MIR4268 Gene

mRNA/cDNA for MIR4268 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4268 Gene

No ASD Table

Relevant External Links for MIR4268 Gene

GeneLoc Exon Structure for
MIR4268
ECgene alternative splicing isoforms for
MIR4268

Expression for MIR4268 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR4268 Gene

Orthologs for MIR4268 Gene

Evolution for MIR4268 Gene

ENSEMBL:
Gene Tree for MIR4268 (if available)
TreeFam:
Gene Tree for MIR4268 (if available)

No data available for Orthologs for MIR4268 Gene

Paralogs for MIR4268 Gene

No data available for Paralogs for MIR4268 Gene

Variants for MIR4268 Gene

Sequence variations from dbSNP and Humsavar for MIR4268 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs874784 -- 219,908,433(-) TAAAT(A/C)CTACC upstream-variant-2KB
rs2385635 -- 219,907,425(+) AGGAA(C/T)GCATA upstream-variant-2KB
rs2385636 -- 219,907,830(+) TTCTG(G/T)ACTCA upstream-variant-2KB
rs2385637 -- 219,908,346(+) TGGGA(A/G/T)TTAAG upstream-variant-2KB
rs2891835 -- 219,906,986(+) AGTGC(C/T)ACCAG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4268 Gene

Variant ID Type Subtype PubMed ID
nsv875878 CNV Loss 21882294
nsv875879 CNV Gain 21882294

Relevant External Links for MIR4268 Gene

HapMap Linkage Disequilibrium report
MIR4268

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR4268 Gene

Disorders for MIR4268 Gene

No disorders were found for MIR4268 Gene.

No data available for UniProtKB/Swiss-Prot for MIR4268 Gene

Publications for MIR4268 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3

Products for MIR4268 Gene

Sources for MIR4268 Gene

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