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Aliases for MIR4268 Gene

Subcategory (RNA class) for MIR4268 Gene


Quality Score for this RNA gene is


Aliases for MIR4268 Gene

  • MicroRNA 4268 2 3 5
  • Hsa-Mir-4268 3

External Ids for MIR4268 Gene

Previous GeneCards Identifiers for MIR4268 Gene

  • GC02U902138
  • GC02M220771

Summaries for MIR4268 Gene

Entrez Gene Summary for MIR4268 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4268 Gene

MIR4268 (MicroRNA 4268) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4268 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4268 Gene

Genomics for MIR4268 Gene

Regulatory Elements for MIR4268 Gene

Enhancers for MIR4268 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02H219906 1 VISTA ENCODE 0.7 -0.9 -897 2.2 CREB1 ATF7 ATF2 MAFK PTPRN MIR4268 LOC105373891
GH02H219912 0.4 ENCODE 0.4 -6.5 -6492 1 CTCF TRIM28 MIR4268 LOC105373891
GH02H219932 0.2 Ensembl 0.3 -25.6 -25636 0.4 LOC105373891 MIR4268
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4268 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4268 Gene

Genomic Locations for MIR4268 Gene
64 bases
Minus strand

Genomic View for MIR4268 Gene

Genes around MIR4268 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4268 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4268 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4268 Gene

Proteins for MIR4268 Gene

Post-translational modifications for MIR4268 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4268 Gene

Domains & Families for MIR4268 Gene

Gene Families for MIR4268 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4268: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4268 Gene

Function for MIR4268 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4268 Gene

Localization for MIR4268 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4268 Gene

Pathways & Interactions for MIR4268 Gene

SuperPathways for MIR4268 Gene

No Data Available

Interacting Proteins for MIR4268 Gene

Gene Ontology (GO) - Biological Process for MIR4268 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4268 Gene

Drugs & Compounds for MIR4268 Gene

No Compound Related Data Available

Transcripts for MIR4268 Gene

mRNA/cDNA for MIR4268 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4268 Gene

No ASD Table

Relevant External Links for MIR4268 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4268 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4268 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4268 Gene

Orthologs for MIR4268 Gene

Evolution for MIR4268 Gene

Gene Tree for MIR4268 (if available)
Gene Tree for MIR4268 (if available)

No data available for Orthologs for MIR4268 Gene

Paralogs for MIR4268 Gene

No data available for Paralogs for MIR4268 Gene

Variants for MIR4268 Gene

Sequence variations from dbSNP and Humsavar for MIR4268 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1000148329 -- 219,906,412(+) ATACA(A/G)GTGCT intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1002220693 -- 219,907,686(+) AATGA(A/G)AAAGT intron-variant, upstream-variant-2KB
rs1003415160 -- 219,907,204(+) TGGTT(C/T)CCAGC intron-variant, upstream-variant-2KB
rs1003675245 -- 219,907,264(+) GGGGG(G/T)TCTCG intron-variant, upstream-variant-2KB
rs1007672099 -- 219,906,765(+) ACTTA(C/T)CATGT intron-variant, upstream-variant-2KB

Relevant External Links for MIR4268 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4268 Gene

Disorders for MIR4268 Gene

Relevant External Links for MIR4268

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4268 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4268 Gene

Publications for MIR4268 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4268 Gene

Sources for MIR4268 Gene

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