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Aliases for MIR4266 Gene

Subcategory (RNA class) for MIR4266 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4266 Gene

  • MicroRNA 4266 2 3 5
  • Hsa-Mir-4266 3

External Ids for MIR4266 Gene

Previous GeneCards Identifiers for MIR4266 Gene

  • GC02U902132
  • GC02M109930

Summaries for MIR4266 Gene

Entrez Gene Summary for MIR4266 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4266 Gene

MIR4266 (MicroRNA 4266) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4266 Gene

Genomics for MIR4266 Gene

Regulatory Elements for MIR4266 Gene

Enhancers for MIR4266 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02G109317 1.4 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -5.3 -5338 3.8 CTCF BHLHE40 HLF ZNF133 CEBPB RAD21 GLIS1 CEBPA SMC3 FOS SH3RF3 MIR4266 GC02M109332
GH02G109329 1.3 Ensembl ENCODE dbSUPER 0.4 -18.0 -17970 4.4 SIN3A RAD21 ZBTB40 GATA2 EGR1 ZNF366 RCOR1 RELB FOS IKZF2 SH3RF3 GC02M109332 MIR4266
GH02G109321 1.1 Ensembl ENCODE dbSUPER 0.4 -8.7 -8693 2.0 CTCF PKNOX1 BHLHE40 SMC3 MAX RAD21 NR2F2 SH3RF3 MIR4266 GC02M109332
GH02G109324 1 Ensembl ENCODE dbSUPER 0.4 -11.9 -11850 2.6 GATA2 BHLHE40 FOS NR2F2 SH3RF3 GC02M109332 MIR4266
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4266 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4266 Gene

Chromosome:
2
Start:
109,313,571 bp from pter
End:
109,313,625 bp from pter
Size:
55 bases
Orientation:
Minus strand

Genomic View for MIR4266 Gene

Genes around MIR4266 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4266 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4266 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4266 Gene

ORGUL Member Location for MIR4266 Gene

ORGUL Member Location for MIR4266 gene

Proteins for MIR4266 Gene

Post-translational modifications for MIR4266 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4266 Gene

Domains & Families for MIR4266 Gene

Gene Families for MIR4266 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4266: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4266 Gene

Function for MIR4266 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4266 Gene

Localization for MIR4266 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4266 Gene

Pathways & Interactions for MIR4266 Gene

SuperPathways for MIR4266 Gene

No Data Available

Interacting Proteins for MIR4266 Gene

Gene Ontology (GO) - Biological Process for MIR4266 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4266 Gene

Drugs & Compounds for MIR4266 Gene

No Compound Related Data Available

Transcripts for MIR4266 Gene

mRNA/cDNA for MIR4266 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4266 Gene

No ASD Table

Relevant External Links for MIR4266 Gene

GeneLoc Exon Structure for
MIR4266
ECgene alternative splicing isoforms for
MIR4266

Expression for MIR4266 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4266 Gene:

MIR4266
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4266 Gene

Orthologs for MIR4266 Gene

Evolution for MIR4266 Gene

ENSEMBL:
Gene Tree for MIR4266 (if available)
TreeFam:
Gene Tree for MIR4266 (if available)

No data available for Orthologs for MIR4266 Gene

Paralogs for MIR4266 Gene

No data available for Paralogs for MIR4266 Gene

Variants for MIR4266 Gene

Sequence variations from dbSNP and Humsavar for MIR4266 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1000014075 -- 109,313,734(+) TGAGC(C/T)GAAAG intron-variant, upstream-variant-2KB
rs1000451274 -- 109,313,527(+) TCGCA(A/G)TGGTC intron-variant, downstream-variant-500B
rs1001705181 -- 109,314,425(+) GGGAG(C/G)AGAGA intron-variant, upstream-variant-2KB
rs1002969667 -- 109,313,375(+) CCCGG(C/G)ATGAG intron-variant, downstream-variant-500B
rs1003308301 -- 109,313,540(+) AAGCA(C/T)CACTG intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4266 Gene

Variant ID Type Subtype PubMed ID
esv28484 CNV loss 19812545
nsv1149522 OTHER inversion 26484159

Relevant External Links for MIR4266 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4266

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4266 Gene

Disorders for MIR4266 Gene

Relevant External Links for MIR4266

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4266

No disorders were found for MIR4266 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4266 Gene

Publications for MIR4266 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4266 Gene

Sources for MIR4266 Gene

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