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Aliases for MIR4261 Gene

Subcategory (RNA class) for MIR4261 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4261 Gene

  • MicroRNA 4261 2 3 5
  • Hsa-Mir-4261 3

External Ids for MIR4261 Gene

Previous GeneCards Identifiers for MIR4261 Gene

  • GC02U902185
  • GC02M010332

Summaries for MIR4261 Gene

Entrez Gene Summary for MIR4261 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4261 Gene

MIR4261 (MicroRNA 4261) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4261 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4261 Gene

Genomics for MIR4261 Gene

GeneHancer (GH) Regulatory Elements for MIR4261 Gene

Promoters and enhancers for MIR4261 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I010201 Enhancer 0.8 FANTOM5 0.4 -8.9 -8899 0.4 ELF3 SOX13 FOXA2 SAP130 MLX ARID4B CEBPG RARA TEAD3 RERE LOC105373424 KLF11 MIR4261 C2orf48
GH02I010159 Enhancer 0.6 ENCODE 0.3 +31.5 31542 3.7 JUN ZSCAN4 MAX ZMYM3 ZIC2 E4F1 ZFHX2 EGR1 ZFP36 ZNF8 ENSG00000206647 GC02M010155 C2orf48 MIR4261 ENSG00000284681
GH02I010170 Enhancer 0.5 ENCODE 0.3 +22.2 22161 0.2 JUND JUN FOS TCF7L2 ENSG00000206647 GC02M010155 MIR4261 C2orf48 ENSG00000284681
GH02I010164 Enhancer 0.4 ENCODE 0.3 +29.3 29281 0.2 CTCF RAD21 GC02M010155 ENSG00000206647 C2orf48 MIR4261 ENSG00000284681
GH02I010163 Enhancer 0.2 ENCODE 0.3 +29.5 29501 0.2 GC02M010155 ENSG00000206647 C2orf48 MIR4261 ENSG00000284681
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4261 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4261 Gene

Genomic Locations for MIR4261 Gene
chr2:10,192,614-10,192,671
(GRCh38/hg38)
Size:
58 bases
Orientation:
Minus strand
chr2:10,332,740-10,332,797
(GRCh37/hg19)

Genomic View for MIR4261 Gene

Genes around MIR4261 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4261 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4261 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4261 Gene

ORGUL Member Location for MIR4261 Gene

ORGUL Member Location for MIR4261 gene

Proteins for MIR4261 Gene

Post-translational modifications for MIR4261 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4261 Gene

Domains & Families for MIR4261 Gene

Gene Families for MIR4261 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4261: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4261 Gene

Function for MIR4261 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4261 Gene

Localization for MIR4261 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4261 Gene

Pathways & Interactions for MIR4261 Gene

SuperPathways for MIR4261 Gene

No Data Available

Interacting Proteins for MIR4261 Gene

Gene Ontology (GO) - Biological Process for MIR4261 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4261 Gene

Drugs & Compounds for MIR4261 Gene

No Compound Related Data Available

Transcripts for MIR4261 Gene

mRNA/cDNA for MIR4261 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4261 Gene

No ASD Table

Relevant External Links for MIR4261 Gene

GeneLoc Exon Structure for
MIR4261
ECgene alternative splicing isoforms for
MIR4261

Expression for MIR4261 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4261 Gene:

MIR4261
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4261 Gene

Orthologs for MIR4261 Gene

Evolution for MIR4261 Gene

ENSEMBL:
Gene Tree for MIR4261 (if available)
TreeFam:
Gene Tree for MIR4261 (if available)

No data available for Orthologs for MIR4261 Gene

Paralogs for MIR4261 Gene

No data available for Paralogs for MIR4261 Gene

Variants for MIR4261 Gene

Sequence variations from dbSNP and Humsavar for MIR4261 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1000096638 -- 10,192,944(-) G/A upstream_transcript_variant
rs1001004888 -- 10,193,818(-) CTCT/CT upstream_transcript_variant
rs1001108240 -- 10,194,086(-) A/G upstream_transcript_variant
rs1001839371 -- 10,194,550(-) C/T upstream_transcript_variant
rs1003075384 -- 10,193,615(-) A/T upstream_transcript_variant

Additional Variant Information for MIR4261 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4261

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4261 Gene

Disorders for MIR4261 Gene

Additional Disease Information for MIR4261

No disorders were found for MIR4261 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4261 Gene

Publications for MIR4261 Gene

  1. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. (PMID: 23535732) Eeles RA … Easton DF (Nature genetics 2013) 3 58
  2. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4261 Gene

Sources for MIR4261 Gene

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