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Aliases for MIR4258 Gene

Subcategory (RNA class) for MIR4258 Gene


Quality Score for this RNA gene is


Aliases for MIR4258 Gene

  • MicroRNA 4258 2 3 5
  • Hsa-Mir-4258 3

External Ids for MIR4258 Gene

Previous GeneCards Identifiers for MIR4258 Gene

  • GC01U902916
  • GC01P154948

Summaries for MIR4258 Gene

Entrez Gene Summary for MIR4258 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4258 Gene

MIR4258 (MicroRNA 4258) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4258 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4258 Gene

Genomics for MIR4258 Gene

Regulatory Elements for MIR4258 Gene

Enhancers for MIR4258 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H154998 1.9 FANTOM5 ENCODE dbSUPER 14.9 +28.8 28759 11.3 MLX YBX1 DMAP1 YY1 ZNF416 ZNF143 SP3 NFYC ZC3H11A PPARGC1A GON4L CLK2 UBAP2L KIAA0907 ENSG00000271267 MSTO1 RUSC1-AS1 THBS3 YY1AP1 FLAD1
GH01H154177 1.8 FANTOM5 ENCODE dbSUPER 14.6 -794.8 -794813 6.8 HDGF PKNOX1 FOXA2 ARNT ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 NUP210L PYGO2 ENSG00000224784 MIR4258 UBAP2L ENSG00000272654 LOC101928120 C1orf189 SNORA58B HAX1
GH01H154606 1.7 FANTOM5 ENCODE dbSUPER 14.6 -367.2 -367229 4.1 HDGF ARNT ARID4B SIN3A FEZF1 YBX1 ZNF2 YY1 ZNF143 ZNF207 CLK2 CHRNB2 ENSG00000271267 UBAP2L ILF2 FLAD1 MIR4258 DAP3P1 RUSC1-AS1 CREB3L4
GH01H155242 1.5 ENCODE dbSUPER 14.6 +268.6 268550 2.9 FEZF1 YBX1 YY1 ZNF416 ZNF143 ZNF548 SP3 ZFP41 MEF2D ZNF610 KIAA0907 GON4L ENSG00000271267 CLK2 MSTO1 MSTO2P THBS3 RUSC1-AS1 LOC101928120 SHC1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4258 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4258 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Locations for MIR4258 Gene

Genomic Locations for MIR4258 Gene
91 bases
Plus strand

Genomic View for MIR4258 Gene

Genes around MIR4258 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4258 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4258 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4258 Gene

Proteins for MIR4258 Gene

Post-translational modifications for MIR4258 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4258 Gene

Domains & Families for MIR4258 Gene

Gene Families for MIR4258 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4258: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4258 Gene

Function for MIR4258 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4258 Gene

Localization for MIR4258 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4258 Gene

Pathways & Interactions for MIR4258 Gene

SuperPathways for MIR4258 Gene

No Data Available

Interacting Proteins for MIR4258 Gene

Gene Ontology (GO) - Biological Process for MIR4258 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4258 Gene

Drugs & Compounds for MIR4258 Gene

No Compound Related Data Available

Transcripts for MIR4258 Gene

mRNA/cDNA for MIR4258 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4258 Gene

No ASD Table

Relevant External Links for MIR4258 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4258 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4258 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4258 Gene:

genes like me logo Genes that share expression patterns with MIR4258: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4258 Gene

Orthologs for MIR4258 Gene

Evolution for MIR4258 Gene

Gene Tree for MIR4258 (if available)
Gene Tree for MIR4258 (if available)

No data available for Orthologs for MIR4258 Gene

Paralogs for MIR4258 Gene

No data available for Paralogs for MIR4258 Gene

Variants for MIR4258 Gene

Sequence variations from dbSNP and Humsavar for MIR4258 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1001555057 -- 154,974,540(+) GAGAA(A/C)TGCCC upstream-variant-2KB
rs1004312072 -- 154,975,717(+) CGCCT(C/T)GGAGG intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1004643005 -- 154,974,640(+) AAGTG(C/T)GGGCG upstream-variant-2KB
rs1004693996 -- 154,974,823(+) CGGGA(A/G)CAATA intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1004798493 -- 154,974,295(+) GGTGC(C/T)GGATC upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for MIR4258 Gene

Variant ID Type Subtype PubMed ID
nsv509502 CNV insertion 20534489

Relevant External Links for MIR4258 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4258 Gene

Disorders for MIR4258 Gene

Relevant External Links for MIR4258

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4258 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4258 Gene

Publications for MIR4258 Gene

  1. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. (PMID: 23535732) Eeles RA … Easton DF (Nature genetics 2013) 3 60
  2. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 60
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4258 Gene

Sources for MIR4258 Gene

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