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Aliases for MIR4256 Gene

Subcategory (RNA class) for MIR4256 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4256 Gene

  • MicroRNA 4256 2 3 5
  • Hsa-Mir-4256 3

External Ids for MIR4256 Gene

Previous GeneCards Identifiers for MIR4256 Gene

  • GC01U902967
  • GC01M113004

Summaries for MIR4256 Gene

Entrez Gene Summary for MIR4256 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4256 Gene

MIR4256 (MicroRNA 4256) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4256 Gene

Genomics for MIR4256 Gene

Regulatory Elements for MIR4256 Gene

Enhancers for MIR4256 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G112462 1.1 ENCODE 0.7 -2.9 -2934 5.0 HDGF PKNOX1 FOXA2 CREB3L1 ARNT WRNIP1 ARID4B SIN3A DMAP1 ZNF2 WNT2B CTTNBP2NL MIR4256
GH01G112461 0.9 ENCODE 0.7 +0.1 140 0.2 FOXA2 ATF1 RAD21 YY1 RARA CREM MIXL1 ZNF263 PPARG NFIL3 MIR4256 GC01P112397
GH01G112456 0.7 ENCODE 0.7 +4.6 4642 2.1 KLF1 NFIB NFIA MAX CEBPB CEBPG RAD21 ZIC2 NFIC GLIS1 CTTNBP2NL WNT2B ENSG00000238761 MIR4256 GC01P112397
GH01G112463 0.4 ENCODE 0.7 +0.5 520 0.2 ZNF263 GATA3 MIR4256 GC01P112397
GH01G112402 1.4 Ensembl ENCODE dbSUPER 0.2 +58.1 58075 4.3 ATF1 BRCA1 ZNF2 KLF7 FOS JUNB TSHZ1 KAT8 MEF2D MAFF WNT2B ENSG00000238761 RHOC PPM1J CTTNBP2NL MOV10 ENSG00000225075 GC01P112397 MIR4256
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4256 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4256 Gene

Chromosome:
1
Start:
112,461,770 bp from pter
End:
112,461,833 bp from pter
Size:
64 bases
Orientation:
Minus strand

Genomic View for MIR4256 Gene

Genes around MIR4256 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4256 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4256 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4256 Gene

ORGUL Member Location for MIR4256 Gene

ORGUL Member Location for MIR4256 gene

Proteins for MIR4256 Gene

Post-translational modifications for MIR4256 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4256 Gene

Domains & Families for MIR4256 Gene

Gene Families for MIR4256 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4256: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4256 Gene

Function for MIR4256 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4256 Gene

Localization for MIR4256 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4256 Gene

Pathways & Interactions for MIR4256 Gene

SuperPathways for MIR4256 Gene

No Data Available

Interacting Proteins for MIR4256 Gene

Gene Ontology (GO) - Biological Process for MIR4256 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4256 Gene

Drugs & Compounds for MIR4256 Gene

No Compound Related Data Available

Transcripts for MIR4256 Gene

mRNA/cDNA for MIR4256 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4256 Gene

No ASD Table

Relevant External Links for MIR4256 Gene

GeneLoc Exon Structure for
MIR4256
ECgene alternative splicing isoforms for
MIR4256

Expression for MIR4256 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4256 Gene:

MIR4256
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4256 Gene

Orthologs for MIR4256 Gene

Evolution for MIR4256 Gene

ENSEMBL:
Gene Tree for MIR4256 (if available)
TreeFam:
Gene Tree for MIR4256 (if available)

No data available for Orthologs for MIR4256 Gene

Paralogs for MIR4256 Gene

No data available for Paralogs for MIR4256 Gene

Variants for MIR4256 Gene

Sequence variations from dbSNP and Humsavar for MIR4256 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000977929 -- 112,463,076(+) TTGGC(C/T)TTATC upstream-variant-2KB
rs1001413153 -- 112,462,465(+) GTCTT(C/T)TCTCC upstream-variant-2KB
rs1003618181 -- 112,463,457(+) AAAAA(G/T)CCAGG upstream-variant-2KB
rs1004524057 -- 112,463,407(+) GAGAC(C/T)AGCCT upstream-variant-2KB
rs1004914004 -- 112,461,903(+) AGCAA(G/T)GTGCT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4256 Gene

Variant ID Type Subtype PubMed ID
esv27061 CNV gain+loss 19812545
nsv506955 OTHER sequence alteration 20534489
nsv831081 CNV loss 17160897

Relevant External Links for MIR4256 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4256

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4256 Gene

Disorders for MIR4256 Gene

Relevant External Links for MIR4256

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4256

No disorders were found for MIR4256 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4256 Gene

Publications for MIR4256 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4256 Gene

Sources for MIR4256 Gene

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