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Aliases for MIR4254 Gene

Subcategory (RNA class) for MIR4254 Gene


Quality Score for this RNA gene is


Aliases for MIR4254 Gene

  • MicroRNA 4254 2 3 5
  • Hsa-Mir-4254 3

External Ids for MIR4254 Gene

Previous GeneCards Identifiers for MIR4254 Gene

  • GC01U903038
  • GC01M032224

Summaries for MIR4254 Gene

Entrez Gene Summary for MIR4254 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4254 Gene

MIR4254 (MicroRNA 4254) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4254 Gene

Genomics for MIR4254 Gene

Regulatory Elements for MIR4254 Gene

Enhancers for MIR4254 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F031759 0.4 ENCODE 0.8 -2.0 -1997 2.4 PKNOX1 ARID4B SIN3A BMI1 GLIS2 EGR1 ZNF366 FOS EGR2 ZBTB11 COL16A1 ENSG00000235790 LOC105378626 TINAGL1 ADGRB2 MIR4254
GH01F031762 0.5 ENCODE 0.8 -4.1 -4090 0.2 ZNF76 SIN3A ZNF48 RAD21 GLIS2 ZNF143 RCOR1 ZNF391 ZNF263 REST ADGRB2 MIR4254
GH01F031761 0.2 ENCODE 0.8 -3.3 -3320 0.2 ZNF366 ZMYM3 ADGRB2 MIR4254
GH01F031750 1.3 Ensembl ENCODE 0.4 +5.6 5564 5.9 HDGF PKNOX1 ARID4B GTF3C2 GLIS2 ZNF143 FOS DEK ZNF263 REST ADGRB2 SNRNP40 TSSK3 EIF3I ENSG00000229447 MIR4254 GC01P031741
GH01F031744 1.3 Ensembl ENCODE 0.4 +11.7 11694 5.3 HDGF CBX3 KLF17 RAD21 GLIS2 ZNF143 CREM EGR2 ZNF362 HCFC1 LOC105378626 TINAGL1 GC01P031741 MIR4254
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4254 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4254 Gene

31,758,660 bp from pter
31,758,735 bp from pter
76 bases
Minus strand

Genomic View for MIR4254 Gene

Genes around MIR4254 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4254 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4254 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4254 Gene

ORGUL Member Location for MIR4254 Gene

ORGUL Member Location for MIR4254 gene

Proteins for MIR4254 Gene

Post-translational modifications for MIR4254 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4254 Gene

Domains & Families for MIR4254 Gene

Gene Families for MIR4254 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4254: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4254 Gene

Function for MIR4254 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4254 Gene

Localization for MIR4254 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4254 Gene

Pathways & Interactions for MIR4254 Gene

SuperPathways for MIR4254 Gene

No Data Available

Interacting Proteins for MIR4254 Gene

Gene Ontology (GO) - Biological Process for MIR4254 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4254 Gene

Transcripts for MIR4254 Gene

mRNA/cDNA for MIR4254 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4254 Gene

No ASD Table

Relevant External Links for MIR4254 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4254 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4254 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4254 Gene:

genes like me logo Genes that share expression patterns with MIR4254: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4254 Gene

Orthologs for MIR4254 Gene

Evolution for MIR4254 Gene

Gene Tree for MIR4254 (if available)
Gene Tree for MIR4254 (if available)

No data available for Orthologs for MIR4254 Gene

Paralogs for MIR4254 Gene

No data available for Paralogs for MIR4254 Gene

Variants for MIR4254 Gene

Sequence variations from dbSNP and Humsavar for MIR4254 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs112380646 -- 31,759,026(+) CGGCC(C/T)CCCCT intron-variant, upstream-variant-2KB
rs112472225 -- 31,760,610(+) GGGGG(A/G)AGGGG intron-variant, upstream-variant-2KB
rs114298295 -- 31,759,990(+) CAGAG(C/T)CTAGC intron-variant, upstream-variant-2KB
rs114655754 -- 31,760,053(+) TTGCC(C/T)GCTGA intron-variant, upstream-variant-2KB
rs116545578 -- 31,760,440(+) TCCCT(C/T)CTGCA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4254 Gene

Variant ID Type Subtype PubMed ID
esv2758930 CNV loss 17122850
nsv1007390 CNV gain 25217958
nsv1007786 CNV gain 25217958
nsv950385 CNV deletion 24416366

Relevant External Links for MIR4254 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4254 Gene

Disorders for MIR4254 Gene

Relevant External Links for MIR4254

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4254 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4254 Gene

Publications for MIR4254 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4254 Gene

Sources for MIR4254 Gene

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