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Aliases for MIR4253 Gene

Subcategory (RNA class) for MIR4253 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4253 Gene

  • MicroRNA 4253 2 3
  • Hsa-Mir-4253 3

External Ids for MIR4253 Gene

Summaries for MIR4253 Gene

Entrez Gene Summary for MIR4253 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4253 Gene

MIR4253 (MicroRNA 4253) is a RNA Gene, and belongs to miRNA RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4253 Gene

Genomics for MIR4253 Gene

Genomic Location for MIR4253 Gene

Start:
22,863,159 bp from pter
End:
22,863,226 bp from pter
Size:
68 bases
Orientation:
Minus strand

Genomic View for MIR4253 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR4253 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4253 Gene

ORGUL Member Location for MIR4253 Gene

ORGUL Member Location for MIR4253 gene

No data available for Regulatory Elements for MIR4253 Gene

Proteins for MIR4253 Gene

Post-translational modifications for MIR4253 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4253 Gene

Domains for MIR4253 Gene

Gene Families for MIR4253 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR4253: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR4253 Gene

Function for MIR4253 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR4253 Gene

Localization for MIR4253 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR4253 Gene

Pathways for MIR4253 Gene

SuperPathways for MIR4253 Gene

No Data Available

Interacting Proteins for MIR4253 Gene

Gene Ontology (GO) - Biological Process for MIR4253 Gene

None

No data available for Pathways by source for MIR4253 Gene

Transcripts for MIR4253 Gene

mRNA/cDNA for MIR4253 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4253 Gene

No ASD Table

Relevant External Links for MIR4253 Gene

GeneLoc Exon Structure for
MIR4253
ECgene alternative splicing isoforms for
MIR4253

Expression for MIR4253 Gene

No Expression Related Data Available

Orthologs for MIR4253 Gene

Evolution for MIR4253 Gene

ENSEMBL:
Gene Tree for MIR4253 (if available)
TreeFam:
Gene Tree for MIR4253 (if available)

No data available for Orthologs for MIR4253 Gene

Paralogs for MIR4253 Gene

No data available for Paralogs for MIR4253 Gene

Variants for MIR4253 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4253 Gene

Variant ID Type Subtype PubMed ID
nsv469829 CNV Loss 16826518
nsv528926 CNV Loss 19592680

Relevant External Links for MIR4253 Gene

HapMap Linkage Disequilibrium report
MIR4253

No data available for Sequence variations from dbSNP and Humsavar for MIR4253 Gene

Disorders for MIR4253 Gene

No disorders were found for MIR4253 Gene.

No data available for UniProtKB/Swiss-Prot for MIR4253 Gene

Publications for MIR4253 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3

Products for MIR4253 Gene

Sources for MIR4253 Gene

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