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Aliases for MIR4252 Gene

Subcategory (RNA class) for MIR4252 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4252 Gene

  • MicroRNA 4252 2 3 5
  • Hsa-Mir-4252 3

External Ids for MIR4252 Gene

Previous GeneCards Identifiers for MIR4252 Gene

  • GC01U902988

Summaries for MIR4252 Gene

Entrez Gene Summary for MIR4252 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4252 Gene

MIR4252 (MicroRNA 4252) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4252 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4252 Gene

Genomics for MIR4252 Gene

Regulatory Elements for MIR4252 Gene

Enhancers for MIR4252 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H006426 0.9 ENCODE 0.7 +2.6 2605 2 PKNOX1 NFIB KLF17 TCF12 GLIS2 GATA2 SCRT2 ZNF143 EGR2 SP3 ESPN RPL22 LOC102724450 RNF207 ACOT7 MIR4252
GH01H006445 1.1 ENCODE dbSUPER 0.4 -15.4 -15420 0 DRAP1 CTCF FOXA2 SAP130 ZSCAN4 ARID4B CDC5L RAD21 RARA TEAD3 PHF13 ENSG00000231868 MIR4252
GH01H006438 0.8 ENCODE 0.4 -8.3 -8310 0 HDGF CTCF LEF1 ZNF146 RB1 KLF17 KMT2B RAD21 ZEB1 ZNF324 ESPN ENSG00000231868 MIR4252
GH01H006440 0.8 ENCODE 0.4 -10.5 -10530 0 CTCF KLF1 ZNF777 KLF17 ZIC2 ZEB1 ZFHX2 EGR1 PATZ1 NFE2 ACOT7 ENSG00000231868 MIR4252
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4252 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4252 Gene

Chromosome:
1
Start:
6,429,834 bp from pter
End:
6,429,896 bp from pter
Size:
63 bases
Orientation:
Minus strand

Genomic View for MIR4252 Gene

Genes around MIR4252 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4252 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4252 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4252 Gene

Proteins for MIR4252 Gene

Post-translational modifications for MIR4252 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4252 Gene

Domains & Families for MIR4252 Gene

Gene Families for MIR4252 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4252: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4252 Gene

Function for MIR4252 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4252
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4252 Gene

Localization for MIR4252 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4252 Gene

Pathways & Interactions for MIR4252 Gene

SuperPathways for MIR4252 Gene

No Data Available

Interacting Proteins for MIR4252 Gene

Gene Ontology (GO) - Biological Process for MIR4252 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4252 Gene

Drugs & Compounds for MIR4252 Gene

No Compound Related Data Available

Transcripts for MIR4252 Gene

mRNA/cDNA for MIR4252 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4252
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4252 Gene

No ASD Table

Relevant External Links for MIR4252 Gene

GeneLoc Exon Structure for
MIR4252
ECgene alternative splicing isoforms for
MIR4252

Expression for MIR4252 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4252 Gene:

MIR4252
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4252 Gene

Orthologs for MIR4252 Gene

Evolution for MIR4252 Gene

ENSEMBL:
Gene Tree for MIR4252 (if available)
TreeFam:
Gene Tree for MIR4252 (if available)

No data available for Orthologs for MIR4252 Gene

Paralogs for MIR4252 Gene

No data available for Paralogs for MIR4252 Gene

Variants for MIR4252 Gene

Sequence variations from dbSNP and Humsavar for MIR4252 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000394965 -- 6,429,351(+) AGGAT(C/T)TGGAT intron-variant, downstream-variant-500B
rs1003928707 -- 6,431,839(+) TTGAG(C/G)ATCTT intron-variant, upstream-variant-2KB
rs1007144909 -- 6,430,326(+) ATCCT(-/GC)CAGGG intron-variant, upstream-variant-2KB
rs1008142205 -- 6,431,419(+) GCCTG(A/G)CCAAC intron-variant, upstream-variant-2KB
rs1008568372 -- 6,431,684(+) GGAAG(-/GAAAGAAAA)GAAAG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4252 Gene

Variant ID Type Subtype PubMed ID
dgv2n27 CNV loss 19166990
dgv80n54 CNV loss 21841781
dgv9n67 CNV gain 20364138
esv25412 CNV gain+loss 19812545
nsv1009548 CNV loss 25217958
nsv482179 CNV gain 20164927
nsv508836 CNV insertion 20534489
nsv545240 CNV loss 21841781
nsv7880 CNV gain+loss 18304495
nsv831536 CNV loss 17160897
nsv954048 CNV deletion 24416366

Relevant External Links for MIR4252 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4252

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4252 Gene

Disorders for MIR4252 Gene

Relevant External Links for MIR4252

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4252

No disorders were found for MIR4252 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4252 Gene

Publications for MIR4252 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff LA … Hart RP (PloS one 2009) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4252 Gene

Sources for MIR4252 Gene

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