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Aliases for MIR4251 Gene

Subcategory (RNA class) for MIR4251 Gene


Quality Score for this RNA gene is


Aliases for MIR4251 Gene

  • MicroRNA 4251 2 3 5
  • Hsa-Mir-4251 3

External Ids for MIR4251 Gene

Previous GeneCards Identifiers for MIR4251 Gene

  • GC01U903019
  • GC01P003044

Summaries for MIR4251 Gene

Entrez Gene Summary for MIR4251 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4251 Gene

MIR4251 (MicroRNA 4251) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4251 Gene

Genomics for MIR4251 Gene

Regulatory Elements for MIR4251 Gene

Enhancers for MIR4251 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F003127 0.4 Ensembl 0.8 -0.3 -275 0.6 GATA3 MIR4251 PIR58969
GH01F003125 0.4 ENCODE 0.8 -2.1 -2061 1.8 SMARCA4 HLF MIR4251 PIR58969
GH01F003126 0.2 Ensembl 0.8 -1.1 -1075 0.2 MIR4251 PIR58969
GH01F003105 0.5 ENCODE 0.3 -22.3 -22274 0.2 RING1 TEAD4 ZNF652 KDM6A MORN1 TP73-AS1 LOC100129534 PIR58969 MIR4251
GH01F003112 0.2 ENCODE 0.3 -15.4 -15367 0.1 MIR4251 PIR58969
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4251 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4251 Gene

3,127,975 bp from pter
3,128,035 bp from pter
61 bases
Plus strand

Genomic View for MIR4251 Gene

Genes around MIR4251 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4251 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4251 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4251 Gene

Proteins for MIR4251 Gene

Post-translational modifications for MIR4251 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4251 Gene

Domains & Families for MIR4251 Gene

Gene Families for MIR4251 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4251: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4251 Gene

Function for MIR4251 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4251 Gene

Localization for MIR4251 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4251 Gene

Pathways & Interactions for MIR4251 Gene

SuperPathways for MIR4251 Gene

No Data Available

Interacting Proteins for MIR4251 Gene

Gene Ontology (GO) - Biological Process for MIR4251 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4251 Gene

Transcripts for MIR4251 Gene

mRNA/cDNA for MIR4251 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4251 Gene

No ASD Table

Relevant External Links for MIR4251 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4251 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4251 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4251 Gene

Orthologs for MIR4251 Gene

Evolution for MIR4251 Gene

Gene Tree for MIR4251 (if available)
Gene Tree for MIR4251 (if available)

No data available for Orthologs for MIR4251 Gene

Paralogs for MIR4251 Gene

No data available for Paralogs for MIR4251 Gene

Variants for MIR4251 Gene

Sequence variations from dbSNP and Humsavar for MIR4251 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs114605885 -- 3,128,146(+) TGTTC(A/G)GAAAT intron-variant, downstream-variant-500B
rs114890269 -- 3,126,270(+) CTGTG(C/T)CTGGG intron-variant, upstream-variant-2KB
rs115650479 -- 3,126,883(+) GGCCC(A/G)GGCCC intron-variant, upstream-variant-2KB
rs11800064 -- 3,126,480(+) CTCAA(C/G)GAGGG intron-variant, upstream-variant-2KB
rs12090422 -- 3,127,457(+) TGCAC(A/G)ATCTG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4251 Gene

Variant ID Type Subtype PubMed ID
nsv951959 CNV deletion 24416366
nsv545099 CNV loss 21841781
nsv428399 CNV gain 18775914
nsv1013792 CNV gain 25217958
nsv1000306 CNV gain 25217958
esv3585038 CNV gain 21293372
esv3583359 CNV gain 25503493
dgv11n100 CNV gain 25217958

Relevant External Links for MIR4251 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4251 Gene

Disorders for MIR4251 Gene

Relevant External Links for MIR4251

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4251 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4251 Gene

Publications for MIR4251 Gene

  1. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4251 Gene

Sources for MIR4251 Gene

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