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Aliases for MIR424 Gene

Subcategory (RNA class) for MIR424 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR424 Gene

  • MicroRNA 424 2 3
  • MIRN424 3 6
  • MIR322 3 6
  • Hsa-Mir-424 3
  • MiRNA424 3

External Ids for MIR424 Gene

Previous HGNC Symbols for MIR424 Gene

  • MIRN424

Previous GeneCards Identifiers for MIR424 Gene

  • GC0XM133521
  • GC0XM133523
  • GC0XM133681
  • GC0XM133686
  • GC0XM133696
  • GC0XM133713

Summaries for MIR424 Gene

Entrez Gene Summary for MIR424 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR424 Gene

MIR424 (MicroRNA 424) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR424 include fragile x-associated tremor/ataxia syndrome. Among its related pathways are miRNAs involved in DDR.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR424 Gene

Genomics for MIR424 Gene

Genomic Location for MIR424 Gene

Start:
134,546,611 bp from pter
End:
134,546,721 bp from pter
Size:
111 bases
Orientation:
Minus strand

Genomic View for MIR424 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR424 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR424 Gene

No data available for Regulatory Elements for MIR424 Gene

Proteins for MIR424 Gene

Post-translational modifications for MIR424 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR424 Gene

Domains for MIR424 Gene

Gene Families for MIR424 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR424: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR424 Gene

Function for MIR424 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR424 Gene

Localization for MIR424 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR424 Gene

Pathways for MIR424 Gene

SuperPathways for MIR424 Gene

Superpath Contained pathways
1 miRNAs involved in DDR
genes like me logo Genes that share pathways with MIR424: view

Pathways by source for MIR424 Gene

1 BioSystems pathway for MIR424 Gene

Interacting Proteins for MIR424 Gene

Gene Ontology (GO) - Biological Process for MIR424 Gene

None

Transcripts for MIR424 Gene

mRNA/cDNA for MIR424 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR424 Gene

No ASD Table

Relevant External Links for MIR424 Gene

GeneLoc Exon Structure for
MIR424
ECgene alternative splicing isoforms for
MIR424

Expression for MIR424 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

genes like me logo Genes that share expressions with MIR424: view

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR424 Gene

Orthologs for MIR424 Gene

Evolution for MIR424 Gene

ENSEMBL:
Gene Tree for MIR424 (if available)
TreeFam:
Gene Tree for MIR424 (if available)

No data available for Orthologs for MIR424 Gene

Paralogs for MIR424 Gene

No data available for Paralogs for MIR424 Gene

Variants for MIR424 Gene

Relevant External Links for MIR424 Gene

HapMap Linkage Disequilibrium report
MIR424

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR424 Gene

Disorders for MIR424 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for MIR424 Gene including...

Search for MIR424 Gene in MalaCards »
genes like me logo Genes that share disorders with MIR424: view

No data available for UniProtKB/Swiss-Prot for MIR424 Gene

Publications for MIR424 Gene

  1. Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells. (PMID: 15325244) Kasashima K. … Kozu T. (Biochem. Biophys. Res. Commun. 2004) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. Patterns of known and novel small RNAs in human cervical cancer. (PMID: 17616659) Lui W.O. … Fire A. (Cancer Res. 2007) 3
  5. The MUC1 and galectin-3 oncoproteins function in a microRNA-dependent regulatory loop. (PMID: 17889671) Ramasamy S. … Kufe D. (Mol. Cell 2007) 3

Products for MIR424 Gene

Sources for MIR424 Gene

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