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Aliases for MIR422A Gene

Subcategory (RNA class) for MIR422A Gene


Quality Score for this RNA gene is


Aliases for MIR422A Gene

  • MicroRNA 422a 2 3
  • Hsa-Mir-422a 3
  • MIRN422A 3

External Ids for MIR422A Gene

Previous HGNC Symbols for MIR422A Gene

  • MIRN422A

Previous GeneCards Identifiers for MIR422A Gene

  • GC15M061952
  • GC15M064163

Summaries for MIR422A Gene

Entrez Gene Summary for MIR422A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR422A Gene

MIR422A (MicroRNA 422a) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR422A Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR422A

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR422A Gene

Genomics for MIR422A Gene

Genomic Location for MIR422A Gene

63,870,930 bp from pter
63,871,019 bp from pter
90 bases
Minus strand

Genomic View for MIR422A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR422A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR422A Gene

ORGUL Member Location for MIR422A Gene

ORGUL Member Location for MIR422A gene

No data available for Regulatory Elements for MIR422A Gene

Proteins for MIR422A Gene

Post-translational modifications for MIR422A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR422A Gene

Domains for MIR422A Gene

Gene Families for MIR422A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR422A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR422A Gene

Function for MIR422A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR422A Gene

Localization for MIR422A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR422A Gene

Pathways for MIR422A Gene

SuperPathways for MIR422A Gene

No Data Available

Interacting Proteins for MIR422A Gene

Gene Ontology (GO) - Biological Process for MIR422A Gene


No data available for Pathways by source for MIR422A Gene

Transcripts for MIR422A Gene

fRNAdb Secondary structures for MIR422A Gene

  • FR118799

mRNA/cDNA for MIR422A Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR422A Gene

No ASD Table

Relevant External Links for MIR422A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR422A Gene

mRNA expression in normal human tissues for MIR422A Gene

genes like me logo Genes that share expressions with MIR422A: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR422A Gene

Orthologs for MIR422A Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR422A Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-422a 36
  • 100 (a)
Species with no ortholog for MIR422A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR422A Gene

Gene Tree for MIR422A (if available)
Gene Tree for MIR422A (if available)

Paralogs for MIR422A Gene

No data available for Paralogs for MIR422A Gene

Variants for MIR422A Gene

Sequence variations from dbSNP and Humsavar for MIR422A Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs7169210 -- 63,872,870(+) ccccc(C/T)taatc upstream-variant-2KB
rs11852632 -- 63,871,972(+) ATCAC(A/G)CCACT upstream-variant-2KB
rs12324106 -- 63,872,494(+) gcacc(C/T)gccac upstream-variant-2KB
rs12324851 -- 63,871,296(+) AGTGC(A/G)CCAGG upstream-variant-2KB
rs12591907 -- 63,872,523(+) TTTGT(A/G)TTTTT upstream-variant-2KB

Relevant External Links for MIR422A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MIR422A Gene

Disorders for MIR422A Gene

No disorders were found for MIR422A Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR422A Gene

Publications for MIR422A Gene

  1. Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells. (PMID: 15325244) Kasashima K. … Kozu T. (Biochem. Biophys. Res. Commun. 2004) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. A putative role of micro RNA in regulation of cholesterol 7alpha-hydroxylase expression in human hepatocytes. (PMID: 20351063) Song K.H. … Chiang J.Y. (J. Lipid Res. 2010) 3
  5. Identification and functional screening of microRNAs highly deregulated in colorectal cancer. (PMID: 22469014) Faltejskova P. … Slaby O. (J. Cell. Mol. Med. 2012) 3

Products for MIR422A Gene

Sources for MIR422A Gene

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