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Aliases for MIR412 Gene

Subcategory (RNA class) for MIR412 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR412 Gene

  • MicroRNA 412 2 3 5
  • Hsa-Mir-412 3
  • Mir-412 3
  • MIRN412 3

External Ids for MIR412 Gene

ORGUL Members for MIR412 Gene

Previous HGNC Symbols for MIR412 Gene

  • MIRN412

Previous GeneCards Identifiers for MIR412 Gene

  • GC14P100841
  • GC14P100931
  • GC14P101532
  • GC14P101560
  • GC14P101593
  • GC14P101632
  • GC14P101660
  • GC14P101694
  • GC14P101732
  • GC14P101772
  • GC14P101830
  • GC14P101970
  • GC14P102167
  • GC14P101274
  • GC14P101891
  • GC14P102206
  • GC14P102374

Summaries for MIR412 Gene

Entrez Gene Summary for MIR412 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR412 Gene

MIR412 (MicroRNA 412) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR412 Gene

Genomics for MIR412 Gene

Regulatory Elements for MIR412 Gene

Enhancers for MIR412 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14F101096 1.1 FANTOM5 ENCODE 11.4 +32.9 32901 3.2 CTCF SUZ12 JUN ZIC2 ZNF335 GLIS2 ZNF366 POLR2A SCRT2 PATZ1 RTL1 LOC105370670 MEG9 MIR369 MIR409 MIR410 MIR412 MIR541 MIR656 MIR154
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR412 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR412 Gene

Chromosome:
14
Start:
101,065,447 bp from pter
End:
101,065,537 bp from pter
Size:
91 bases
Orientation:
Plus strand

Genomic View for MIR412 Gene

Genes around MIR412 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR412 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR412 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR412 Gene

Proteins for MIR412 Gene

Post-translational modifications for MIR412 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR412 Gene

Domains & Families for MIR412 Gene

Gene Families for MIR412 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR412: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR412 Gene

Function for MIR412 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR412 Gene

Localization for MIR412 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR412 Gene

Pathways & Interactions for MIR412 Gene

SuperPathways for MIR412 Gene

No Data Available

Interacting Proteins for MIR412 Gene

Gene Ontology (GO) - Biological Process for MIR412 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR412 Gene

Transcripts for MIR412 Gene

mRNA/cDNA for MIR412 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR412 Gene

No ASD Table

Relevant External Links for MIR412 Gene

GeneLoc Exon Structure for
MIR412
ECgene alternative splicing isoforms for
MIR412

Expression for MIR412 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR412 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR412 Gene:

MIR412
genes like me logo Genes that share expression patterns with MIR412: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR412 Gene

Orthologs for MIR412 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR412 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-412 35
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-412 35
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir412 35
  • 93 (a)
OneToOne
Species where no ortholog for MIR412 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR412 Gene

ENSEMBL:
Gene Tree for MIR412 (if available)
TreeFam:
Gene Tree for MIR412 (if available)

Paralogs for MIR412 Gene

No data available for Paralogs for MIR412 Gene

Variants for MIR412 Gene

Sequence variations from dbSNP and Humsavar for MIR412 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs10144688 -- 101,065,899(+) TGAGC(C/T)GATGG downstream-variant-500B, upstream-variant-2KB
rs10144831 -- 101,065,880(+) GACGC(A/G)GCAGC downstream-variant-500B, upstream-variant-2KB
rs112268641 -- 101,063,994(+) GTGCC(C/T)TTCGT upstream-variant-2KB
rs112727398 -- 101,065,091(+) CTACC(G/T)GGGTC upstream-variant-2KB
rs113509474 -- 101,064,341(+) ATGCC(C/T)GCCCC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR412 Gene

Variant ID Type Subtype PubMed ID
esv3635521 CNV gain 21293372
nsv1040993 CNV gain 25217958
nsv509551 CNV insertion 20534489
nsv565859 CNV gain 21841781
nsv565860 CNV gain 21841781

Relevant External Links for MIR412 Gene

Human Gene Mutation Database (HGMD)
MIR412
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR412

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR412 Gene

Disorders for MIR412 Gene

Relevant External Links for MIR412

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR412

No disorders were found for MIR412 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR412 Gene

Publications for MIR412 Gene

  1. The repertoire and features of human platelet microRNAs. (PMID: 23226537) PlAc H. … Provost P. (PLoS ONE 2012) 3 64
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
  4. Clustering and conservation patterns of human microRNAs. (PMID: 15891114) Altuvia Y. … Margalit H. (Nucleic Acids Res. 2005) 3 64

Products for MIR412 Gene

Sources for MIR412 Gene

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